Theresa Unseld,Tobias Bluhmki,Jan Beyersmann et al.
Theresa Unseld et al.
Landmarking is an alternative to complex multistate models when the aim is to calculate dynamic predictions. We develop the concept of landmarking for the case of left truncation and competing risks from the application background of drug s...
High-Dimensional Bayesian Semiparametric Models for Small Samples: A Principled Approach to the Analysis of Cytokine Expression Data [0.03%]
高维贝叶斯半参模型在小样本中的应用：细胞因子表达数据分析的一种建模方法
Giovanni Poli,Raffaele Argiento,Amedeo Amedei et al.
Giovanni Poli et al.
In laboratory medicine, due to the lack of sample availability and resources, measurements of many quantities of interest are commonly collected over a few samples, making statistical inference particularly challenging. In this context, sev...
Confirmatory Adaptive Designs for Clinical Trials With Multiple Time-to-Event Outcomes in Multi-state Markov Models [0.03%]
多重时间事件终点的多状态马尔可夫模型确认自适应设计临床试验研究
Moritz Fabian Danzer,Andreas Faldum,Thorsten Simon et al.
Moritz Fabian Danzer et al.
The analysis of multiple time-to-event outcomes in a randomized controlled clinical trial can be accomplished with existing methods. However, depending on the characteristics of the disease under investigation and the circumstances in which...
Firth-Type Penalized Methods of the Modified Poisson and Least-Squares Regression Analyses for Binary Outcomes [0.03%]
修正泊松回归和最小二乘回归的FIRTH罚则方法在二分类终点的研究中的应用
Satoshi Uno,Hisashi Noma,Masahiko Gosho
Satoshi Uno
The modified Poisson and least-squares regression analyses for binary outcomes have been widely used as effective multivariable analysis methods to provide risk ratio and risk difference estimates in clinical and epidemiological studies. Ho...
A Novel Method for Nonparametric Statistical Inference for Niche Overlap in Multiple Species [0.03%]
一种关于多物种生态位重叠的非参数统计推断新方法
Patrick B Langthaler,Kai-Philipp Gladow,Oliver Krüger et al.
Patrick B Langthaler et al.
The understanding of species interactions and ecosystem dynamics hinges upon the study of ecological niches. Quantifying the overlap of Hutchinsonian-niches has garnered significant attention, with many recent publications addressing the is...
Testing for Sufficient Follow-Up in Censored Survival Data by Using Extremes [0.03%]
利用极值理论检验截尾生存数据的随访是否充分
Ping Xie,Mikael Escobar-Bach,Ingrid Van Keilegom
Ping Xie
In survival analysis, it often happens that some individuals, referred to as cured individuals, never experience the event of interest. When analyzing time-to-event data with a cure fraction, it is crucial to check the assumption of "suffic...
A Flexible Adaptive Lasso Cox Frailty Model Based on the Full Likelihood [0.03%]
基于全似然的灵活自适应LASSO Cox脆弱性模型
Maike Hohberg,Andreas Groll
Maike Hohberg
In this work, a method to regularize Cox frailty models is proposed that accommodates time-varying covariates and time-varying coefficients and is based on the full likelihood instead of the partial likelihood. A particular advantage of thi...
Jan Gertheiss,David Rügamer,Bernard X W Liew et al.
Jan Gertheiss et al.
Functional data analysis (FDA) is a statistical framework that allows for the analysis of curves, images, or functions on higher dimensional domains. The goals of FDA, such as descriptive analyses, classification, and regression, are genera...
Post-Estimation Shrinkage in Full and Selected Linear Regression Models in Low-Dimensional Data Revisited [0.03%]
低维数据下整体和选取线性回归模型的后估计收缩效应研究
Edwin Kipruto,Willi Sauerbrei
Edwin Kipruto
The fit of a regression model to new data is often worse due to overfitting. Analysts use variable selection techniques to develop parsimonious regression models, which may introduce bias into regression estimates. Shrinkage methods have be...
Meta-Analysis of Diagnostic Accuracy Studies With Multiple Thresholds: Comparison of Approaches in a Simulation Study [0.03%]
一种诊断准确性研究的meta分析方法：基于多重截断点的模拟研究比较各类方法
Antonia Zapf,Cornelia Frömke,Juliane Hardt et al.
Antonia Zapf et al.
The development of methods for the meta-analysis of diagnostic test accuracy (DTA) studies is still an active area of research. While methods for the standard case where each study reports a single pair of sensitivity and specificity are ne...