Contrasting Global and Patient-Specific Regression Models via a Neural Network Representation [0.03%]
基于神经网络表示的全局和患者特定回归模型的比较
Max Behrens,Daiana Stolz,Eleni Papakonstantinou et al.
Max Behrens et al.
When developing clinical prediction models, it can be challenging to balance between global models that are valid for all patients and personalized models tailored to individuals or potentially unknown subgroups. To aid such decisions, we p...
Reducing the Effect of Correlated Additive Measurement Errors on Regression Model With no Ancillary Study [0.03%]
降低相关性加性测量误差对无辅助研究回归模型的影响
Zhiqiang Cao,Man Yu Wong
Zhiqiang Cao
To adjust the effect of additive measurement error on estimation and hypothesis testing, one needs some information on the measurement error model, that is, an ancillary study (e.g., validation study, calibration study, or replicates study)...
Extending t linear mixed models for longitudinal data with non-ignorable dropout applied to AIDS studies [0.03%]
具有不可忽略缺失的纵向数据的t混合效应模型及其在艾滋病研究中的应用
Yu-Chen Yang,Wan-Lun Wang,Luis M Castro et al.
Yu-Chen Yang et al.
One typical missing pattern in longitudinal data is dropout in the sense that some participants may withdraw prematurely and never return. Dropout is generally regarded as a non-ignorable mechanism when the probability of the occurrence of ...
A Novel Approach to the Design and Sample Size Planning of Animal Experiments Based on Effect Estimation [0.03%]
基于效应估计的动物实验设计和样本量规划的新方法
Dario Zocholl,Henrike Solveen,Matthias Schmid
Dario Zocholl
Animal experiments are often purely exploratory, with little to no data available to support the planning phase. Nonetheless, ethical guidelines demand scientifically sound planning, particularly regarding sample size determination based on...
Impact of Treatment Effect Heterogeneity on the Estimation of Individualized Treatment Rules for Count Outcomes [0.03%]
处理效应异质性对计数结果个体化治疗决策的影响研究
Xiaotong Jiang,Gabrielle Simoneau,Bora Youn et al.
Xiaotong Jiang et al.
There is growing interest in tailoring treatment decisions to individual patient characteristics, but few studies have examined the implementation and performance of individualized treatment rules (ITRs) for count data. Our objective was to...
Tsz Pang Yuen,Eni Musta
Tsz Pang Yuen
In order to estimate the proportion of "immune" or "cured" subjects who will never experience failure, a sufficiently long follow-up period is required. Several statistical tests have been proposed in the literature for assessing the assump...
Bivariate Quantile Residual Life Functions for Estimating Immunological and Virological Recovery in HIV Patients [0.03%]
HIV患者免疫学和病毒学恢复的双变量分位数残差寿命函数估计
Ruhul Ali Khan,Musie Ghebremichael
Ruhul Ali Khan
Monitoring both immunological and virological outcome measures provides the most accurate and meaningful assessment of the human immunodeficiency virus (HIV) treatment effectiveness. However, evaluating treatment efficacy based solely on ei...
Wei Cao,Shanshan Wang,Hanyu Zhong
Wei Cao
Statistical modeling and estimation for heterogeneous censored survival data is of great practical importance, as exemplified by applications in bio-medicine. Censored quantile and expectile regression methods offer useful tools to capture ...
Generalizing the Finkelstein-Schoenfeld Test to Incorporate Multiple Alternating Thresholds [0.03%]
兼有多个交替阈值的芬克尔斯坦-许恩费尔德检验的推广方法
Yunhan Mou,Tassos Kyriakides,Scott Hummel et al.
Yunhan Mou et al.
Composite endpoints consisting of both terminal and nonterminal events, such as death and hospitalization, are frequently used in cardiovascular clinical trials. The Finkelstein-Schoenfeld (FS) test provides a way to employ a hierarchical s...
Deriving Duration Time From Occupancy Data-A Case Study in the Length of Stay in Intensive Care Units for COVID-19 Patients [0.03%]
从占用数据推导持续时间：COVID-19患者重症监护病房住院时长的案例研究
Martje Rave,Göran Kauermann
Martje Rave
This paper focuses on drawing information on underlying processes, which are not directly observed in the data. In particular, we work with data in which only the total count of units in a system at a given time point is observed, but the u...