The potential therapeutic effects of exosomes derived from bone marrow mesenchymal stem cells on ileum injury of a rat sepsis model (histological and immunohistochemical study) [0.03%]
骨髓间充质干细胞来源外泌体对脓毒症大鼠空肠损伤潜在治疗作用的组织及免疫组化研究
Heba M Elnegris,Abeer A Abdelrahman,Eman S El-Roghy
Heba M Elnegris
Sepsis denotes a serious high mortality concern. The study was designed to evaluate the effect of mesenchymal stem cell exosomes (MSC-exosomes) on the evolution of the animal model of sepsis. In this study, 36 rats were distributed into thr...
The effects of the combination of temozolomide and Eribulin on T98G human glioblastoma cell line: an ultrastructural study [0.03%]
替莫唑胺和埃洛楚单药及其联合应用对人胶质母细胞瘤T98G细胞系影响的超微结构观察
Gamze Tanriverdi,Belisa Kaleci,Furkan Yavuz et al.
Gamze Tanriverdi et al.
Glioblastoma tumors are the most aggressive primary brain tumors that develop resistance to temozolomide (TMZ). Eribulin (ERB) exhibits a unique mechanism of action by inhibiting microtubule dynamics during the G2/M cell cycle phase. We uti...
Morphological and histopathological changes of maternal levetiracetam on the cerebellar cortex of the offspring of albino rat [0.03%]
氨己烯酸致大鼠母体脑干损伤后后代小脑皮层的形态和组织学变化研究
Safaa M Hanafy
Safaa M Hanafy
Levetiracetam (LEV) is being used by women with reproductive-age epilepsy at a significantly higher rate. The purpose of the study was to assess how levetiracetam treatment during pregnancy affected the offspring's weight and cerebellum. Fo...
Chronic liver fibrosis induction in aging causes significant ultra-structural deterioration in liver and alteration on immune response gene expressions in liver-spleen axis [0.03%]
慢性肝纤维化诱导衰老导致肝脏超微结构恶化及肝脾轴免疫反应基因表达改变
Zeynal Mete Karaca,Gamze Karaca,Başak Kayhan et al.
Zeynal Mete Karaca et al.
The relationship between damage to the liver and spleen by aging and the immune response status in these two organs, which are anatomically and immunologically interconnected, is unknown. The authors investigated the histopathological, ultr...
Can the analysis of chromatin texture and nuclear fractal dimensions serve as effective means to distinguish non-invasive follicular thyroid neoplasm with papillary-like nuclear features from other malignancies with follicular pattern in the thyroid?: a study [0.03%]
染色质纹理和细胞核分形维数分析能否有效区分具有乳头状类似核特征的非侵袭性滤泡甲状腺肿瘤与其他甲状腺滤泡型恶性肿瘤？一项研究
Geet Bhuyan,Anjumoni Rabha
Geet Bhuyan
Objective: Thyroid carcinoma ranks as the 9th most prevalent global cancer, accounting for 586,202 cases and 43,636 deaths in 2020. Computerized image analysis, utilizing artificial intelligence algorithms, emerges as a p...
Unveiling renal pathology's potential: exploring a rare subtype of amyloid - apolipoprotein CII amyloidosis in the youngest patient: a case report and literature review [0.03%]
揭开肾病理的潜在面纱：罕见亚型淀粉样变性的病例报道及文献回顾——apoCⅡ淀粉样变性在最小患者中的表现形式
Yiqin Zuo,Fiona Hanly,Duo Li et al.
Yiqin Zuo et al.
In this clinical case report, we present a rare subtype of amyloidosis, apolipoprotein CII (apo CII), which was diagnosed through a renal biopsy and subsequently confirmed by identifying the p.K41T mutation via germline DNA sequencing. Upon...
Infection as a trigger of acute, transient glomerular deposition of clonal immunoglobulins [0.03%]
感染作为克隆型免疫球蛋白在肾小球急性暂时沉积的触发因素
Bangchen Wang,Micah Schub,Derrick L Robinson et al.
Bangchen Wang et al.
Glomerular deposition of monoclonal IgM, frequently in the form of intracapillary pseudothrombi, can be seen in Waldenström macroglobulinemia (WM) and type I cryoglobulinemia (CG). They are typically associated with plasma cell or B-lympho...
Hydralazine use can be associated with IgM-dominated immune complex-mediated glomerulonephritis [0.03%]
hydralazine与IgM为主的免疫复合物介导的肾小球肾炎相关
Ping L Zhang,Brandon D Metcalf,Sarang Khan et al.
Ping L Zhang et al.
Context: IgM-dominant immune complex-mediated glomerulonephritis (IgM-dominant ICMGN) is a rare renal entity, characterized by a membranoproliferative pattern by light microscopy, dominant IgM staining by immunofluorescen...
Metformin modulates autophagic pathway in renal fibrosis induced by carbon tetrachloride in adult male albino rats [0.03%]
二甲双胍通过调节自噬途径减轻CCl4诱导的雄性Sprague Dawley大鼠肾纤维化中的自噬异常及相关炎症反应的作用研究
Amal T Abou-Elghait,Rania M Al Adly,Eman Radwan et al.
Amal T Abou-Elghait et al.
Backgrounds: Chronic kidney disease (CKD) is a global public health problem. All progressive chronic kidney disease (CKD) is characterized by tubulointerstitial fibrosis. Exposure to high concentrations of carbon tetrachl...
"Ultrastructural changes of platelets in COVID-19 and chronic viral hepatitis patients " [0.03%]
COVID-19和慢性病毒性肝炎患者血小板的超微结构改变
Ayat SalahEldin Mohamed Hassan,Sahar Samir Abdelmaksoud Abo Gaziah,Hieba Gamal Ezzelregal Awad et al.
Ayat SalahEldin Mohamed Hassan et al.
Platelet-viral interactions are evolving as a new concern. Coagulation disorder is a major consequence of the COVID-19 infection. In chronic hepatitis virus infections, defect in coagulation factors, thrombocytopenia and platelet function a...