Heterozygous missense mutation of the fibrinogen gene associated with cryptogenic liver disease in a 15-months-old Canadian caucasian child [0.03%]
儿童杂合半胱氨酸变异的纤维蛋白原基因与隐源性肝病的相关性研究
Mohit Kehar,Robert J Klaassen,Consolato M Sergi
Mohit Kehar
Hepatic fibrinogen storage disease is an uncommon autosomal dominant hereditary illness marked by hypofibrinogenemia and the accumulation of variant fibrinogen in the hepatic endoplasmic reticulum. We present an asymptomatic 15-month-old ma...
Christopher-Rasheem Mcmillan
Christopher-Rasheem Mcmillan
A comparative study on the effect of melatonin and orlistat combination versus orlistat alone on high fat diet-induced hepatic changes in the adult male albino rats (a histological and morphometric study) [0.03%]
褪黑素联合奥利司他与单用奥利司他对高脂饮食诱导的成年雄性雪貂肝损伤影响的比较研究（一项组织学和形态学的研究）
Sayed M El-Sayed,Gehan A El-Sayed,Mansour M A et al.
Sayed M El-Sayed et al.
Background: Nonalcoholic fatty liver disease (NAFLD) is the extremely usual reason of chronic liver disease, extending from simple hepatic steatosis (HS), nonalcoholic steatohepatitis (NASH) to advanced hepatic fibrosis a...
Comparative Study
Ultrastructural pathology. 2025 Jan 2;49(1):20-38. DOI:10.1080/01913123.2024.2438380 2025
Ultrastructural organization of the liver of rat pups in early postnatal ontogenesis when pregnant and lactating rats are kept on a low-protein diet [0.03%]
低蛋白饮食对孕期及哺乳期大鼠幼仔肝超微结构的影响研究
Elena G Pershina,Ksenia N Morozova,Nataliya P Bgatova
Elena G Pershina
Protein deficiency in the diet during pregnancy and lactation has a serious impact on the offspring by programming a predisposition to such serious diseases as hypertension and type 2 diabetes mellitus. In our study, we examined liver ultra...
Metformin ameliorates diabetes-induced hepatic ultrastructural damage and the immune biomarker CD86 and inflammation in rats [0.03%]
二甲双胍通过减轻免疫生物标志物CD86和炎症来改善糖尿病大鼠肝超微结构损伤
Mohammad Y Alshahrani,Fahad S Al Amri,Mohammed A Alzahrani et al.
Mohammad Y Alshahrani et al.
Diabetes is a known inducer of hepatic ultrastructural alterations, and the expression of the immune biomarker that involves in T-cell immunity, cluster of differentiation 86 (CD86) is increased in diabetic patients with liver cirrhosis. Th...
Construction of an animal model of autism based on interaction between cerebellar histological, immunohistochemical, and biochemical changes in adult male albino rat [0.03%]
基于成年雄性白鼠小脑组织学、免疫组织化学及生化变化交互作用的自闭症动物模型构建
Eman Saeed Mokhtar Tawfeek,Salwa Aly Abou Elez Gawish,Wafaa Saad Hamed et al.
Eman Saeed Mokhtar Tawfeek et al.
Methods: Twelve pregnant female rats were divided into a control group and a valproic acid (VPA) treated group (injected intraperitoneally on embryonic day 12 with 600 mg/kg body weight of VPA). Neurobehavioral tests were...
Ida Perrotta
Ida Perrotta
Cell death is an important process that supports morphogenesis during development and tissue homeostasis during adult life by removing damaged or unwanted cells and its dysregulation is associated with numerous disease states. There are dif...
Efficacy of ozone versus mesenchymal stem cell-derived microvesicles in ameliorating testicular changes after hypothyroidism in adult albino rats: a histological and immunohistochemical study [0.03%]
臭氧与间充质干细胞衍生微泡改善阿尔比诺大鼠甲减后睾丸变化的疗效：一项组织学和免疫组织化学研究
Magdy F Gawish,Samia A Abd El-Baset,Salma S Shalabi et al.
Magdy F Gawish et al.
This study was performed to: detect the histological, immunohistochemical, and biochemical alterations that may occur in the testes of adult rats in induced hypothyroidism. And to investigate which one, ozone or MSCs-MVs have better therape...
The therapeutic efficacy of adipose mesenchymal stem cell-derived microvesicles versus infliximab in a dextran sodium sulfate induced ulcerative colitis rat model [0.03%]
脂肪来源的间充质干细胞微囊泡与英夫利西治疗溃疡性结肠炎模型疗效的比较研究
Sahar F Shaban,Eman A Abdel-Fattah,Manar M Ali et al.
Sahar F Shaban et al.
Ulcerative colitis (UC) is a chronic relapsing intestinal inflammation that is becoming of increasing incidence worldwide and has insufficient treatment. Therefore, finding effective therapies remains a priority. A dextran sodium sulfate co...
Felicia M Masetla,Mia-Jeanne Van Rooy,June C Serem et al.
Felicia M Masetla et al.
Streptozotocin (STZ) is a commonly used compound for the induction of type 2 diabetes (T2D) in animal models, but its effects on non-pancreatic tissues like the lungs are not well understood. This study aimed to examine the histopathologica...