Real-world implementation of North American and SIOP strategies for the treatment of Wilms tumor in Uruguay [0.03%]
威尔士肿瘤治疗的北美和SIOP策略在乌拉圭的实施情况
Diana Vargas,Luisa Chantada,Bruno Cuturi et al.
Diana Vargas et al.
Wilms tumor has been selected as an index tumor by the WHO Global Initiative for Childhood Cancer with the aim to improve cure rates worldwide. Nevertheless, there is a scarcity of published data on outcomes beyond those of the major cooper...
Levofloxacin prophylaxis in pediatric oncology and hematopoietic stem cell transplantation: a literature review [0.03%]
儿科肿瘤学和造血干细胞移植中左氧氟沙星的预防作用：文献综述
Jane Koo,Jeffrey Hord,Craig Gilliam et al.
Jane Koo et al.
Bloodstream infections (BSI) are one of the leading causes of morbidity and mortality in children and young adults receiving chemotherapy for malignancy or undergoing hematopoietic stem cell transplantation (HSCT). Antibiotic prophylaxis is...
Oncological pediatric early warning score: a dedicated tool to predict patient's clinical deterioration and need for pediatric intensive care treatment [0.03%]
儿童肿瘤预警评分：一种预测患儿病情恶化和儿科重症监护治疗需求的专用工具
Teresa Maccarana,Marta Pillon,Veronica Bertozzi et al.
Teresa Maccarana et al.
Pediatric oncohematological patients frequently require PICU admission during their clinical history. The O-PEWS is a specific score developed to predict the need for PICU admission of oncohematological children. This study aimed at i) desc...
Utilization of supportive care medications and opportunities for pre-emptive pharmacogenomic testing in pediatric and young adults with leukemia [0.03%]
儿童和年轻成人白血病患者支持性药物的使用及预判型药物基因组学检测的机会评估
Colleen M Sakon,Carmina Sales,Selsbiel Mertami et al.
Colleen M Sakon et al.
This study aimed to evaluate the utilization of drugs with pharmacogenomic guidelines (PGx-drugs) for personalized dosing in pediatric leukemia. A retrospective observational study of pediatric leukemia patients admitted between 2009-2019 a...
Pseudohyperkalemia in pediatric patients with newly diagnosed hematological malignancies [0.03%]
新诊断的血液系统恶性肿瘤儿童患者的假高钾血症
Ting-Chu Li,Wei-Cheng Chan,Ming-Chin Tsai et al.
Ting-Chu Li et al.
Patients with newly diagnosed hematological malignancies often present with a considerable cellular burden, leading to complications including hyperkalemia. However, pseudohyperkalemia, arising from in vitro cell lysis, can pose challenges ...
Clonal hematopoiesis of indeterminate potential is rare in pediatric patients undergoing autologous stem cell transplantation [0.03%]
异基因干细胞移植儿科患者中潜在克隆性造血罕见
Mutlu Kartal-Kaess,Axel Karow,Ulrike Bacher et al.
Mutlu Kartal-Kaess et al.
Clonal hematopoiesis of indeterminate potential (CHIP) describes recurrent somatic gene mutations in the blood of healthy individuals, associated with higher risk for hematological malignancies and higher all-cause mortality by cardiovascul...
Hospital acquired venous thromboembolism in children with sickle cell disease [0.03%]
镰形细胞病儿童的医院相关性静脉血栓症事件
Shreya Agarwal,Kayla L Foster,Shaniqua J Anum et al.
Shreya Agarwal et al.
Sickle cell disease (SCD) is well recognized as a hypercoagulablestate, however, it remains unclear whether a subgroup of children with SCD at higher risk of venous thromboembolic event (VTE) during hospitalization may benefit from thrombop...
Adjuvant immune checkpoint inhibitor therapy may benefit pediatric patients with stage III melanoma and sentinel lymph node positivity: a case series [0.03%]
辅助免疫检查点抑制剂治疗可能有助于III期黑色素瘤且区域淋巴结阳性的儿童患者：病例报告系列
Acacia Bowden,Jeanette Zambito,Jinia El-Feghaly et al.
Acacia Bowden et al.
Melanoma is the most common skin cancer in children. While the current literature establishes treatment protocols for adult-type melanoma, very few pediatric-specific studies exist, and children are often excluded from melanoma clinical tri...
Myelofibrosis associated with immune cytopenia in an infant: a diagnostic and therapeutic challenge [0.03%]
与免疫性细胞减少症相关的婴儿骨髓纤维化的诊断和治疗挑战
Yessenia L Molina,Luis Blasco-Santana,Alejandro Sanz et al.
Yessenia L Molina et al.
Therapeutic efficacy of RAS inhibitor trametinib using a juvenile myelomonocytic leukemia patient-derived xenograft model [0.03%]
应用幼年型粒单核细胞白血病患者来源异种移植模型研究RAS抑制剂曲马替尼的疗效
Alex Q Lee,Hiroaki Konishi,Masami Ijiri et al.
Alex Q Lee et al.
Juvenile myelomonocytic leukemia (JMML) is an aggressive pediatric leukemia with few effective treatments and poor outcomes even after stem cell transplantation, the only current curative treatment. We developed a JMML patient-derived xenog...