The prevalence of opioid misuse diagnostic codes in children with sickle cell disease [0.03%]
血红蛋白病患儿滥用阿片类药物的诊断编码流行情况
Ann-Marie Tantoco,Sherif M Badawy,Cheryl K Lee et al.
Ann-Marie Tantoco et al.
Hospitalized patients with sickle cell disease (SCD) may use opioid medications for both acute and chronic pain management. Use of these medications may unintentionally generate diagnostic codes for opioid misuse including "opioid use," "op...
Safety and Tolerability of a 3-Day Fosaprepitant Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients: Results of an Open-Label, Single-Arm Phase 4 Trial [0.03%]
用于预防儿童癌症患者化疗引起的恶心呕吐的 fosaprepitant 三天用药方案的安全性和耐受性：一项开放标签、单臂、Ⅳ期临床试验结果
Juan Luis Garcia Leon,Cara DiCristina,Ruji Yao et al.
Juan Luis Garcia Leon et al.
Convenient multiday dosing of antiemetic regimens for the prevention of chemotherapy-induced nausea and vomiting (CINV) are needed in pediatric patients, who are more likely than adults to be treated with emetogenic chemotherapy over multip...
Current approaches in development and implementation of medical education strategies among pediatric hematology/oncology fellowship programs [0.03%]
儿科血液学/肿瘤学研究生项目中医学教育策略的发展和实施的当前方法
Samantha Scanlon,Kristina Dzara,Rebecca Ronsley
Samantha Scanlon
Application of evidenced-based practices is often lacking in medical education. Increased recognition that methods of knowledge delivery based in relevant learning theories are more effective has led to improved ability to meet the needs of...
Chloé Goncalves,Jérémie Rouger,Isabelle Pellier et al.
Chloé Goncalves et al.
In adults, there is a link between socioeconomic status (SES) and cancer prognosis, notably due to increased time to diagnosis (TTD) in deprived population leading to the dissemination of the disease. In children, such an association has no...
Long-Term Survey of Japanese Children with Recurrent Nephroblastoma: A Report from Japan Children's Cancer Group [0.03%]
日本儿童复发性肾母细胞瘤的长期调查结果（日本儿童肿瘤研究会报告）
Hiroshi Yagasaki,Yoshiki Katsumi,Miwako Nozaki et al.
Hiroshi Yagasaki et al.
In prospective Japanese studies of pediatric renal tumors, 5-year event-free survival and overall survival (OS) for patients with nephroblastoma ranges from 75-90% and 89-97%, respectively. However, treatments strategies for recurrent nephr...
Why are Higher CD34+ Cell Doses Associated with Improved Outcomes among Pediatric Patients Undergoing Autologous Hematopoietic Stem Cell Transplant for Central Nervous System Tumors - But Not for High-Risk Neuroblastoma? [0.03%]
为何较高的CD34+细胞剂量与自体造血干细胞移植治疗中枢神经系统肿瘤的儿童患者的改善结局相关-但不是高危神经母细胞瘤？
Tristan E Knight,Larisa Broglie,Akshay Sharma et al.
Tristan E Knight et al.
Temporal trends in pediatric cancer mortality: rare cancers lag behind more common cancers [0.03%]
儿童癌症死亡率的 temporal趋势：罕见癌症落后于常见癌症
Brian R Englum,Shalini Sahoo,Theodore W Laetsch et al.
Brian R Englum et al.
Temporal trends demonstrate improved survival for many types of common pediatric cancer. Studies have not examined improvement in very rare pediatric cancers or compared these improvements to more common cancers. In this cohort study of the...
Assessment of cancer predisposition syndromes in children with leukemia and solid tumors: germline-genomic profiling and clinical features in a series of cases [0.03%]
儿童白血病和实体瘤患者癌症易感综合征的评估：一系列病例的基因组测序及临床特征分析
Minu Singh,Prateek Bhatia,Pankaj Sharma et al.
Minu Singh et al.
Cancer predisposition syndromes (CPS) are a group of genetic disorders that increase the risk of various cancers. Identifying CPS has a significant impact on the treatment plan, screening and follow-up strategy, and genetic counseling of th...
Soluble cytotoxic T-lymphocyte antigen-4 (sCTLA-4) in children with immune cytopenia: relation to disease activity [0.03%]
儿童免疫性细胞减少症中可溶性细胞毒T淋巴细胞相关抗原-4(sCTLA-4)与疾病活动的关系研究
Sara Mostafa Makkeyah,Nayera Hazaa El-Sherif,Mona Fathey Hasan et al.
Sara Mostafa Makkeyah et al.
Cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) is a costimulatory receptor exhibiting a potent inhibitory signal on antigen-activated immune responses. A soluble form, sCTLA-4, has been identified and was found to be increased in seve...
Long-Term Survival and Immune Reconstitution of Donor-Derived Chimeric Antigen Receptor T-Cell Therapy for Childhood Molecular Relapse of B-Cell Acute Lymphoblastic Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation [0.03%]
allo-HSCT后儿童B细胞急性淋巴细胞白血病分子复发接受供者来源的嵌合抗原受体T细胞治疗后的长期生存及免疫重建
Guan-Hua Hu,Ying-Xi Zuo,Pan Suo et al.
Guan-Hua Hu et al.
Measurable residual disease (MRD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an independent risk factor for relapse in patients with acute lymphoblastic leukemia (ALL). This study aimed to assess the efficacy, s...