Aberrant serum lipid levels predict clinical outcomes in patients with neuroblastoma [0.03%]
血清脂质水平异常可预测神经母细胞瘤患者的临床结局
Zhixia Yue,Wen Zhao,Chao Duan et al.
Zhixia Yue et al.
This study aimed to explore how serum lipid levels are related to clinical features and outcomes in neuroblastoma(NB). We analyzed data from 169 patients diagnosed with NB, focusing on their serum lipid levels and how these relate to diseas...
Adherence to the febrile neutropenia protocol in pediatric leukemia patients at a Brazilian Cancer Center-A retrospective audit [0.03%]
巴西癌症中心儿科急性白血病患者发热性中性粒细胞减少症治疗方案的依从性-回顾性审核
Jessica Talita Mariana Wicthoff Raniero,Anita Cassoli Cortez,Cecilia Maria Lima da Costa et al.
Jessica Talita Mariana Wicthoff Raniero et al.
Pediatric patients with hematologic cancers, especially those undergoing chemotherapy, are highly vulnerable to infections and febrile neutropenia (FN). Noncompliance with FN protocols often leads to excessive antibiotic use, raising the ri...
The novel XIAP Lys396Ter variant alters mitochondrial membrane potential and endoplasmic reticulum intensity in monocytes of two XIAP-deficient patients [0.03%]
XIAP突变患者的单核细胞线粒体膜电位和内质网强度的改变
Benedetta Elena Di Majo,Fabiola Guerra,Mario Mauri et al.
Benedetta Elena Di Majo et al.
Relapse patterns among children and adolescents with Kaposi sarcoma in Malawi [0.03%]
马拉维儿童和青少年卡波西肉瘤的复发模式
Toni Chanroo,Allison Silverstein,Casey L McAtee et al.
Toni Chanroo et al.
Kaposi sarcoma (KS) is a common childhood cancer in Malawi, but few studies have explored clinical characteristics of relapsed disease. We aimed to characterize clinical patterns of relapse to improve treatment and, ultimately, long-term su...
Retrospective analysis of 26 children with severe autoimmune hemolytic anemia treated with transfusions of red blood cells [0.03%]
回顾性分析26例重型自身免疫性溶血性贫血患儿输注红细胞治疗效果
Xue Tang,Xiaoqing Li,Yang Wang et al.
Xue Tang et al.
Autoimmune hemolytic anemia (AIHA) is rare inchildren. Little is known about the efficiency of red blood cells (RBCs) transfusions and the risk of reactions among children with severe AIHA. This article describes the clinical features and o...
Hemorrhagic complications and outcomes of children with acute promyelocytic leukemia at initial hospital admission: a multicenter cohort study [0.03%]
急性早幼粒细胞白血病初治住院患儿的出血并发症及结局：多中心队列研究
Balagangadhar Totapally,Ariella Barhen,Guillermo De Angulo
Balagangadhar Totapally
Acute promyelocytic leukemia (APL) is an uncommon subtype of acute myeloid leukemia that is associated with hemorrhagic complications and early death. Our primary objective was to describe the frequency of hemorrhagic complications and outc...
Alpelisib in pediatric PIK3CA- and TIE-2-mutant vascular anomalies: a case series on safety, efficacy, and drug exposure [0.03%]
PIK3CA和TIE-2突变儿科血管畸形中阿尔佩利西布的药效、安全性和药物暴露：病例系列研究
Albert Etingin,Amandine Remy,Thomas Sonea et al.
Albert Etingin et al.
Alpelisib was recently approved by the FDA for the management of pediatric patients with PIK3CA-related overgrowth spectrum. However, this medication was approved in the absence of pediatric pharmacokinetic data, as a fixed 50 mg dose, with...
Evaluation of psychosocial outcomes of pediatric cancer survivors in a resource limited setting [0.03%]
资源匮乏条件下的儿童肿瘤幸存者心理社会结果的评估
Divya Rajkumar,Venkatraman RadhaKrishnan,Gargi Das et al.
Divya Rajkumar et al.
Pediatric cancer survivorship presents significant challenges globally, with varying survival rates and survivorship care models across different income settings. This present study focuses on the psycho-social outcomes of pediatric cancer ...
Bone mineral status at diagnosis οf children with hematologic malignancy [0.03%]
儿童血液系统恶性肿瘤诊断时的骨矿物状况
Maria Nikita,Artemis Doulgeraki,Margarita Baka et al.
Maria Nikita et al.
Reduced bone mineral density (BMD) has been reported during and after treatment of children with hematologic malignancies. However, little is known about the skeletal status of these patients at diagnosis. The aim of this study was to evalu...
Primary gonadal failure in children with intracranial brain tumors treated with high dose alkylating agents and radiation sparing therapy: an institutional case series [0.03%]
大剂量烷化剂和放疗对脑肿瘤患儿原发性生殖腺功能衰竭的影响：机构病例系列研究
Sylvia Cheng,Sarah Riedlinger,Rebecca Ronsley et al.
Sylvia Cheng et al.
Treatment of young children with brain tumors may require the use of high dose chemotherapy with alkylating agents to avoid craniospinal irradiation. The objective of this study is to describe the probability of primary gonadal failure (PGF...