Yunyan He,Weixiong Lin,Jianming Luo
Yunyan He
Fetal hemoglobin (HbF) plays a dominant role in ameliorating morbidity and mortality of hemoglobinopathies. The authors performed a replicated study following the genome-wide association study (GWAS) guidelines to identify the genetic mecha...
Abdalla Khalil,Ayelet Ben Barak,Irena Zaidman et al.
Abdalla Khalil et al.
Correlation between chemokines released from umbilical cord blood-derived mesenchymal stem cells and engraftment of hematopoietic stem cells in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice [0.03%]
人脐带血间充质干细胞分泌的趋化因子与非肥胖糖尿病重度联合免疫缺陷小鼠造血干细胞植入的关系研究
Yoo Hun Noh,Young Sook Yim,Dong Hyun Kim et al.
Yoo Hun Noh et al.
Umbilical cord blood (UCB)-derived mesenchymal stem cells (MSCs) enhance the engraftment of human hematopoietic stem cells (HSCs) when they are cotransplanted in animal and human studies. However, the type of MSCs that preferentially facili...
Coexistence of translocation(1,19) and the Philadelphia chromosome in a child's first presentation of chronic myeloid leukemia in blast crisis treated with dasatinib [0.03%]
达沙替尼治疗儿童慢性粒细胞白血病急变期并存易位(1;19)和费城染色体
Mark A Eckardt,Vivian Y Chang,Nagesh P Rao et al.
Mark A Eckardt et al.
Chronic myelogenous leukemia (CML) constitutes less than 5% of childhood leukemias. The authors describe a rare case of a 14-year-old boy who presented with CML in blast crisis. Unique to this patient was the evidence of both breakpoint clu...
Javier El-Bietar,Catherine Bollard
Javier El-Bietar
Epstein-Barr virus (EBV)-associated lymphomas represent a broad spectrum of diseases and can be characterized by their pattern of viral latency. These pathologies display the importance of healthy T cell-mediated control of the EBV-infected...
Leukemia and lymphoma incidence in children in Alberta, Canada: a population-based 22-year retrospective study [0.03%]
加拿大艾伯塔省儿童白血病和淋巴瘤的发病率：一项基于人群的22年回顾性研究
Ketan Kulkarni,Kent Stobart,Adrienne Witol et al.
Ketan Kulkarni et al.
There is a paucity of published literature on the epidemiology of childhood acute leukemias and lymphomas in Canada. This study was designed to describe children and youth (age
Management of severe refractory thrombocytopenia in dengue hemorrhagic fever with intravenous anti-D immune globulin [0.03%]
静脉注射抗D免疫球蛋白治疗登革出血热难治性血小板减少症的疗效观察
Gaurav Kharya,Satya Prakash Yadav,Satyendra Katewa et al.
Gaurav Kharya et al.
Dengue hemorrhagic fever (DHF) is a potentially lethal complication of dengue fever due to shock and/or bleeding. Bleeding in DHF is due to thrombocytopenia and/or coagulopathy. The authors present their experience of usage of intravenous a...
Secondary hemophagocytosis in 3 patients with organic acidemia involving propionate metabolism [0.03%]
丙酸血症患者发生二次噬血细胞综合征3例报告及机制探讨
M Gokce,O Unal,B Hismi et al.
M Gokce et al.
Hemophagocytic lymphohistiocytosis (HLH) may develop secondary to infections, malignancies, immune deficiency syndromes, and rheumatologic and metabolic disorders. Associations between HLH and inborn errors of metabolism, including lysinuri...
Evaluation of hepatic iron overload in Chinese children with β-thalassemia major [0.03%]
中国地中海贫血患儿肝脏铁过载评估研究
Lu-Hong Xu,Jian-Pei Fang,Hong-Gui Xu et al.
Lu-Hong Xu et al.
Patients with β-thalassemia major require long-term blood transfusions, resulting in hepatic iron overload. Thirty-five Chinese children with β-thalassemia major were recruited in the present studies. Hepatic iron overload was evaluated b...
Cytotoxic function of umbilical cord blood natural killer cells: relevance to adoptive immunotherapy [0.03%]
脐带血自然杀伤细胞的细胞毒性功能与过继免疫治疗的相关性研究
Syh-Jae Lin,Ming-Ling Kuo
Syh-Jae Lin
Decreased graft-versus-host disease (GVHD), ease of accessibility, and sustained engraftment encourage the use of umbilical cord blood (UCB) as an alternative source to bone marrow for immune reconstitution in children with leukemia. Natura...