Prognostic impact of onset timing on response to methylprednisolone pulse therapy for idiopathic pneumonia syndrome after allogeneic hematopoietic cell transplantation [0.03%]
起病时间对allo-HSCT后特发性肺炎综合征甲基强的松龙冲击治疗反应的影响：一项预后研究
Hirozumi Sano,Masato Yanagi,Daiki Hori et al.
Hirozumi Sano et al.
Idiopathic pneumonia syndrome (IPS) is a serious complication following allogeneic hematopoietic cell transplantation (HCT), often treated with methylprednisolone (mPSL) pulse therapy. However, treatment responses vary. This study aimed to ...
Leveraging artificial intelligence for decision-making in pediatric progressive and refractory solid tumors [0.03%]
利用人工智能进行儿科进展性和难治性实体瘤决策制定
Oz Mordechai,Inbar Meir,Einav Blanche et al.
Oz Mordechai et al.
Pediatric patients with progressive and refractory solid tumors face a challenging prognosis. Despite advancements in treatments like immunotherapy and targeted therapy, survival rates remain low for certain tumor types. Decision-making in ...
Prognostic value of serum albumin recovery in pediatric cancer patients: insights into cancer-cachexia and survival outcomes [0.03%]
儿童癌症患者血清白蛋白恢复的预后价值：对癌 cachexia 和生存结果的新认识
Debabrata Mohapatra,Shubhashree Acharya,Prashant Prabhakar et al.
Debabrata Mohapatra et al.
Hypoalbuminemia and cancer cachexia predict poor survival in adult cancers, with limited studies in pediatrics. Also, the serial recovery kinetics of serum albumin and its effect on cancer outcomes are unknown. This study investigated trend...
Prasad Iyer,Rajat Bhattacharyya,Gaurav Kharya
Prasad Iyer
Hematopoietic stem cell transplantation (HSCT) is a therapeutic modality for pediatric malignancies and inherited and acquired hematological, immunological, and metabolic disorders. The efficacy of HSCT depends on many factors, including co...
Long-Term Health Outcomes in Male Survivors of Childhood Cancer After Hematopoietic Stem Cell Transplantation: A Registry-Based Study [0.03%]
基于注册表的儿童期癌症男性幸存者造血干细胞移植后的长期健康结局研究
Mikael Koskela,Melanie Korhonen,Kirsi Jahnukainen
Mikael Koskela
Late effects are a major concern after pediatric hematopoietic stem cell transplantation (HSCT), but data on health outcomes beyond early adulthood remain scarce. This study assessed long-term morbidity and mortality in one of the earliest ...
Combination of oral temozolomide and etoposide as palliative chemotherapy for recurrent or progressive neuroblastoma [0.03%]
替莫唑胺联合依托泊苷治疗复发或进展神經母细胞瘤的姑息化疗效果评估
Katsutsugu Umeda,Satoshi Saida,Hirokazu Kobushi et al.
Katsutsugu Umeda et al.
We retrospectively analyzed the clinical outcomes of seven patients receiving palliative treatment with oraltemozolomide (TMZ)/etoposide (ETP) for recurrent or progressive neuroblastoma (NB). Patients received a median of three cycles of TM...
Katarzyna Kuchalska,Anna Gotz-Więckowska,Walentyna Balwierz et al.
Katarzyna Kuchalska et al.
Neuroblastoma (NBL) is a tumor that develops from sympathetic ganglia and most frequently occurs in young children. In mediastinal and cervical cases, Horner syndrome (HS) may occur as a symptom or a surgical complication. The study aimed t...
Review of OEPA/COPDAC regimen in pediatric Hodgkin lymphoma; institutional experience from a low middle-income country [0.03%]
OEPA/COPDAC方案治疗儿童霍奇金淋巴瘤的回顾性分析——来自低收入和中等收入国家的经验
Ayesha Siddiq,Eman Anwar,Arsalan Siddiqui et al.
Ayesha Siddiq et al.
Pediatric Hodgkin lymphoma (HL) treatment has increasingly shifted toward response-adapted protocols, aiming to minimize radiotherapy and employ intensive chemotherapy such as OEPA/COPDAC. We retrospectively reviewed treatment outcomes and ...
Vitamin D receptor gene polymorphisms and 25-hydroxyvitamin D levels: association with cerebrovascular disease in sickle cell anemia [0.03%]
维生素D受体基因多态性和25-羟维生素D水平与镰状细胞贫血患者脑血管疾病的关系
Gabriela S Arcanjo,Jéssica V G F Batista,Jéssica M F Oliveira et al.
Gabriela S Arcanjo et al.
Sickle cell anemia (SCA) is associated with a high prevalence of cerebrovascular complications, such as ischemic stroke, particularly at young ages. Among various molecules, vitamin D has been implicated in stroke occurrence. By binding to ...
Prospective Evaluation of KIT Mutations and Long-Term Outcomes in Pediatric Core Binding Factor Acute Myeloid Leukemia: A Single Institutional Study in China [0.03%]
KIT突变对儿童核壳型急性髓系白血病预后影响及长期结局的单中心研究
Bei Hou,Feifei Yang,Ruidong Zhang et al.
Bei Hou et al.
The overall incidence of core binding factor acute myeloid leukemia (CBF-AML) in pediatric patients has been reported to be 19%-44.3%. However, the prognostic role of KIT mutations in pediatric CBF-AML remains controversial. This study aime...