ESC guidelines 2025 on cardiovascular disease and pregnancy: considerations and future perspectives [0.03%]
2025年欧洲心脏病学会妊娠心血管疾病指南：注意事项和未来展望
Eloisa Arbustini,Fausta Beneventi,Antonio Bozzani et al.
Eloisa Arbustini et al.
Pregnancy in women with cardiovascular disease (CVD) represents a distinct clinical condition, as the physiological adaptations of pregnancy may interact with underlying cardiac pathology in variable and sometimes unpredictable ways. Conseq...
Aldosterone synthesis inhibitors in resistant hypertension: the BaxHTN trial [0.03%]
顽固性高血压患者中醛固酮合酶抑制剂的效果：BaxHTN试验
Giovanna Gallo,Maurizio Volterrani,Giuliano Tocci et al.
Giovanna Gallo et al.
Inhibitors of the renin-angiotensin-aldosterone system remain foundational therapies for arterial hypertension across major international guidelines. Their effectiveness, however, may be partially attenuated by the phenomenon of aldosterone...
Unexpected therapeutic scenarios: initiating SGLT2 inhibitors in de novo heart failure without echocardiography [0.03%]
意外的治疗场景：在新发心力衰竭且没有超声心动图的情况下开始使用钠-葡萄糖共转运蛋白2抑制剂
Luca Antonio Felice Di Odoardo,Emilia D&#x;Elia,Edoardo Sciatti et al.
Luca Antonio Felice Di Odoardo et al.
In the field of heart failure, sodium-glucose cotransporter 2 inhibitors (SGLT2-i) have demonstrated robust efficacy and have received a Class I, Level A recommendation for reducing the risk of heart failure hospitalizations and cardiovascu...
Maria Perotto,Carola Pio Loco Detto Gava,Federico Garoia et al.
Maria Perotto et al.
Cardiomyopathy classification remains challenging due to their extraordinary clinical, morphological, and genetic heterogeneity. As diagnostic technologies evolve, so too must the frameworks by which we conceptualize and communicate these d...
Fausto Castriota,Angelo Squeri,Roberto Nerla
Fausto Castriota
Severe mitral regurgitation (MR) is associated with an unfavourable prognosis, characterized by high mortality and reduced quality of life. Mitral surgery remains the gold standard for degenerative MR in patients with low operative risk, en...
Marco Marini,Francesca Coraducci,Matilda Shkoza et al.
Marco Marini et al.
Cardiogenic shock (CS) is a life-threatening syndrome characterized by systemic tissue hypoperfusion due to inadequate cardiac output. Despite advances in cardiovascular care, mortality remains high, particularly during the first hours and ...
Forgotten tricuspid valve? In cases of severe regurgitation, I prefer early surgery [0.03%]
被遗忘的三尖瓣吗？在严重反流的情况下，我更倾向于早期手术
Nicola Buzzatti,Francesco Maisano,Ottavio Alfieri
Nicola Buzzatti
After decades of neglect, awareness of the clinical importance of tricuspid regurgitation has recently increased, partly due to the expansion of transcatheter therapies. Historically, tricuspid valve surgery has been associated with high op...
Focus on lipoprotein(a) [0.03%]
聚焦脂蛋白(a)
Marta Biolo,Camilla Portinari,Camilla Goffi et al.
Marta Biolo et al.
Lipoprotein(a) [Lp(a)] is a causal and independent cardiovascular risk factor for atherosclerotic cardiovascular disease and calcific aortic valve stenosis, with elevated levels observed in approximately 20% of the general population. Plasm...
PCSK9 inhibitors conquer primary prevention: the VESALIUS-CV study [0.03%]
PCSK9抑制剂在一级预防中占优势：VESALIUS-CV研究
Laura Gatto,Maria Pia Di Bitonto,Lorenzo Scalia et al.
Laura Gatto et al.
Elevated low-density lipoprotein cholesterol (LDL-C) represents a key causal factor in atherosclerotic cardiovascular disease. Robust evidence demonstrates that early, marked, and sustained reduction of LDL-C is associated with a significan...
Pharmacological therapy in the obese patient: is it only a matter of fat loss? [0.03%]
肥胖患者的药物治疗：仅仅是为了减脂吗？
Claudio Borghi,Alessio Bragagni
Claudio Borghi
Obesity is a chronic, multifactorial condition strongly associated with increased cardiovascular and metabolic risk, as well as the development of systemic complications. Recent evidence from randomized controlled trials-including SELECT, S...