Preserving renal function: gliflozins, GLP1 agonists, and antialdosterones [0.03%]
肾脏功能保护：钠-gliflozin、GLP1受体激动剂和抗醛固酮药物的作用
Gennaro Cice
Gennaro Cice
For a long time, a prognostic and therapeutic fatalism accompanied even the most motivated clinicians when they had to deal with a progressive decline in renal function; the modest successes were nullified by an increasingly aggressive synd...
Nicolò Azzola Guicciardi,Alessandro Beneduce,Francesco Maisano
Nicolò Azzola Guicciardi
Moderate or severe aortic insufficiency (AI) is a relatively rare condition but with significant clinical implications, especially in elderly patients at high surgical risk. Although surgical aortic valve replacement remains the gold standa...
Serious iatrogenic complications: pulmonary vein stenosis after ablation of atrial fibrillation [0.03%]
导管消融治疗房颤后严重的医源性并发症-肺静脉狭窄
Antonio L Bartorelli,Francesca Di Lenarda,Massimo Mantica et al.
Antonio L Bartorelli et al.
Pulmonary vein stenosis (PVS) has been recognized as a clinical entity complicating radiofrequency or cryoenergy ablation for atrial fibrillation. Although reduced by technical and procedural advancements, this complication portends remarka...
Discordance between aortic valve gradient and area: do I trust the significant gradient? [0.03%]
主动脉瓣压力阶差和瓣口面积不一致时，如何判断有意义的压力阶差？
Manuela Muratori,Ali Sarah Ghulam,Paola Gripari et al.
Manuela Muratori et al.
Aortic stenosis is an increasingly relevant pathology not only for its high prevalence in the population (especially elderly), but also because in recent decades traditional surgery has been accompanied by transcatheter aortic valve implant...
Leonardo Calò,Cinzia Crescenzi,Fabiana Romeo et al.
Leonardo Calò et al.
Electrocardiogram may play a crucial role in the diagnostic workup of different cardiomyopathies. Electrocardiogram abnormalities in impulse generation and transmission may be an early marker of these insidious pathologies. Some findings ar...
Elena Bacigalupi,Luca Scorpiglione,Matteo Perfetti et al.
Elena Bacigalupi et al.
Tricuspid edge-to-edge repair (T-TEER) has emerged as a promising treatment option for severe functional tricuspid regurgitation (TR) in patients unsuitable for surgery. Recent findings from randomized clinical trials consistently demonstra...
Alessandro Bufi,Valeria Caso
Alessandro Bufi
Large vessel occlusion stroke is a significant cause of disability and mortality. Mechanical thrombectomy (MT) has greatly improved outcomes when performed within 6 h of symptom onset. However, many patients present beyond this window, whic...
Factor XI inhibitors and atrial fibrillation: imminent breakthrough or false start? [0.03%]
因子XI抑制剂与房颤：即将突破还是虚假起点？
Carmelo Raffo,Giacinto Di Leo,Davide Capodanno
Carmelo Raffo
Atrial fibrillation (AF) is a common cardiac arrhythmia associated with a high risk of thrombo-embolic events, such as ischaemic stroke and systemic embolism, which require anticoagulant treatment. Vitamin K antagonists and direct oral anti...
Ilaria Finamora,Carlo Colaiaco,Karim Mahfouz et al.
Ilaria Finamora et al.
The evidence that conventional right ventricular pacing can result in the development of cardiomyopathy and heart failure over time has prompted the search for alternative pacing sites. Conduction system pacing (CSP) represents an attempt t...
What has changed in the management of chronic ischaemic heart disease? The new European Society of Cardiology Guidelines 2024 [0.03%]
慢性缺血性心脏病的管理发生了哪些变化？2024年欧洲心脏病学会指南解读
Domenico Galante,Giulia La Vecchia,Antonio Maria Leone et al.
Domenico Galante et al.
The 2024 ESC Guidelines for the management of chronic coronary syndromes expand the concept of CCS (chronic coronary syndrome), adopting a broader vision that includes structural and functional alterations throughout the coronary tree. A si...