Microcystin-LR Disrupts Bile Acid Homeostasis, Driving Cholestatic Liver Injury and Gallstones via FXR/SHP Antagonism [0.03%]
Jun He,Wen-Li Xu,Feng Chen et al.
Jun He et al.
Bile acids (BAs) are vital for liver health, and their dysregulation causes hepatobiliary disorders. Microcystins (MCs) are pervasive hepatotoxins in freshwaters worldwide that threaten public health; yet, their effects on BA homeostasis─p...
Integrated Resource Recovery from Sludge for Synergizing Quorum Sensing and Interspecies Electron Transfer in Anaerobic Treatment [0.03%]
Longyi Lv,Ziyin Wei,Boxiang Sun et al.
Longyi Lv et al.
Anaerobic granular sludge (AnGS) plays a vital role in treating organic wastewater, yet its performance is limited by methanogens' poor resistance and inefficient interspecies electron transfer. Emerging quorum sensing (QS) is a promising a...
Pollutant-Diet Interactions Drive Distinct Mechanisms of Tetrabromobisphenol A-Induced Hepatic Insulin Resistance in Zebrafish [0.03%]
Xinxin Ren,Yongyong Guo,Bingjie Li et al.
Xinxin Ren et al.
Tetrabromobisphenol A (TBBPA), a widely used brominated flame retardant, bioaccumulates in the liver and disrupts glucolipid homeostasis, yet its diet-dependent metabolic effects remain unclear. This study investigated how differing dietary...
Degradation of Toxins and Metabolites of Cyanobacteria and Micropollutants during Biological Sand Filtration [0.03%]
Valentin Rougé,Anne Dax,Oliver Köster et al.
Valentin Rougé et al.
Cyanobacteria produce complex mixtures of secondary metabolites (cyano-metabolites), some of which are toxic and pose a growing concern for water utilities. While physical treatments such as filtration can efficiently remove cells, their ly...
Tailoring Dense Polyester Nanofiltration Membranes for Selective Mineral Retention in Health-Oriented Potable Water Production [0.03%]
Jiulong Yin,QingNan Ouyang,Na Li et al.
Jiulong Yin et al.
Retaining essential minerals (e.g., Ca2+, Mg2+) is critical for generating healthy, palatable water. However, conventional polyamide nanofiltration (NF) membranes suffer from excessive mineral salt rejection, chlorine susceptibility, and sc...
Causal-Inference Machine Learning for Unveiling Hydroxyl Radical Reactivity with Antibiotics in Water Purification [0.03%]
Shihua Zou,Zonglin Li,Yicen Dai et al.
Shihua Zou et al.
Understanding hydroxyl radical (HO·) reactivity with organic pollutants is crucial for optimizing advanced oxidation processes in water purification. Machine learning (ML) models have been developed to predict HO· reactivity but often pro...
Sulfate Radical-Initiated Aqueous Oxidation of Biomass Burning Tracers: A Potential Source of HULIS and aqSOA [0.03%]
Ru Chen,Xiang Li,Xiaoyan Zhou et al.
Ru Chen et al.
Given the limited studies on the aqueous-phase oxidation of methoxyphenols by sulfate radicals (SO4•-), this work provided the first insight into the formation of aqueous-phase secondary organic aerosols (aqSOA) and the optical properties ...
Selective Activation of PMS by a Single-Atom MOF in Confined Space: Hydrogen Bond-Assisted Nonradical Pathway and Continuous Flow Verification [0.03%]
Sihan Zhou,Yun Yang,Meng Li et al.
Sihan Zhou et al.
Conventional peroxymonosulfate (PMS) activation often depends on nonselective radicals, limiting efficiency and selectivity. Precise nonradical pathways based on singlet oxygen (1O2) or high-valent metal oxo species under mild conditions re...
Qiankun Chen,Huaqiao Gui,Zhibo Xie et al.
Qiankun Chen et al.
Aircraft exhaust creates intense, localized pollutant plumes near airports, and the emitted particles undergo rapid postemission aging and exert both direct and indirect climate effects. Their climatic influence hinges on how individual par...
Dual Effects of In Situ Free Nitrous Acid Accumulation on Membrane Fouling in Acidic Membrane Bioreactors [0.03%]
Zheng Kong,Zhiyao Wang,Yunqian Song et al.
Zheng Kong et al.
Acid-tolerant ammonia-oxidizing bacteria (AOB)-based technologies show promise for sustainable wastewater treatment. Membrane bioreactors (MBRs) are suitable for retaining acid-tolerant AOB, but membrane fouling under acidic conditions rema...