Quantitative structure-property relationship in a combinatorial Bi4-xLaxTi3O12 (0<or=x<or=1) thin film array obtained with microbeam XRD and Raman spectroscopy [0.03%]
Bi4-xLaxTi3O12(x＝0至0．8)的组成-结构-介电性能关系研究
Ki Woong Kim,Min Ku Jeon,Tai Suk Kim et al.
Ki Woong Kim et al.
A ferroelectric Bi4-xLaxTi3O12 (BLT) thin film library was fabricated from Bi2O3/La2O3/TiO2 multilayers using a multitarget RF-sputtering system equipped with an automated shutter. The polarization-electric field and structure were mapped a...
Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry [0.03%]
微波固相炔烃环三聚反应在组合化学中的应用研究
Douglas D Young,Lakshminath Sripada,Alexander Deiters
Douglas D Young
Microwave-enhanced efficient synthesis of diversified 3,6-disubstituted pyridazines [0.03%]
微波促进的3,6-取代哒嗪的有效合成
Shijun Lin,Zhende Liu,Youhong Hu
Shijun Lin
A new strategy toward fused-pyridine heterocyclic scaffolds: Bischler-Napieralski-type cyclization, followed by sulfoxide extrusion reaction [0.03%]
一类新的稠杂环合成策略：Bischler-Napieralski反应串联砜基排退出炉反应构筑稠吡啶类化合物
Xianxiu Xu,Sigen Guo,Qun Dang et al.
Xianxiu Xu et al.
Method development was completed for a new strategy to obtain fused-pyridine heterocyclic scaffolds. The synthetic route entails a Bischler-Napieralski-type reaction as the key step, followed by a sulfoxide extrusion reaction. The reactions...
Automated liquid-liquid extraction workstation for library synthesis and its use in the parallel and chromatography-free synthesis of 2-alkyl-3-alkyl-4-(3H)-quinazolinones [0.03%]
自动化液液萃取工作站用于库合成及其在平行和不需色谱纯化的2-烷基-3-芳基-4(3H)-喹唑啉酮的合成中的应用
Mercedes Carpintero,Marta Cifuentes,Rafael Ferritto et al.
Mercedes Carpintero et al.
An automated liquid-liquid extraction workstation has been developed. This module processes up to 96 samples in an automated and parallel mode avoiding the time-consuming and intensive sample manipulation during the workup process. To valid...
Synthesis and applications of a novel polymer-supported EEDQ reagent [0.03%]
一种新型聚合物固相EEDQ试剂的合成及应用研究
Ramesh Kakarla,Guo Li,Samuel W Gerritz
Ramesh Kakarla
A simple synthetic protocol for a novel polymer-supported EEDQ reagent is reported. This reagent promotes solution-phase amide bond formation without any additives or base, as well as the selective coupling of aliphatic amines with acids in...
Solid-phase synthesis of novel trimers containing a phenylstatine core and analysis by high-resolution magic angle spinning [0.03%]
固相合成新型苯基硫氨三亚元化合物并用高分辨率魔角旋转进行分析
Lorena Taboada,Lourdes Prieto,Paloma Vidal et al.
Lorena Taboada et al.
Here we describe a multistep solid-phase synthetic approach for the addition of amino acid residues to both the C- and N-termini of a phenylstatine core, yielding a library aimed at the development of structure-activity relationships in the...
Three-component combinatorial synthesis of a substituted 6H-pyrido[2',1':2,3]imidazo- [4,5-c]isoquinolin-5(6H)-one library with cytotoxic activity [0.03%]
一类具有抗肿瘤活性的取代6H-吡啶并[2',1':2,3]咪唑并[4,5-c]异喹啉-5(6H)-酮三组分组合库的构建
Tao Meng,Zhixiang Zhang,Dingyu Hu et al.
Tao Meng et al.
Parallel synthesis of indolylquinones and their cell-based insulin mimicry [0.03%]
基于细胞的胰岛素模拟吲哚喹啉的平行合成
Michael C Pirrung,Zhitao Li,Erika Hensley et al.
Michael C Pirrung et al.
A synthetic route to bis-indolyldihydroxybenzoquinones was adapted for parallel organic synthesis. The route involves selective conjugate addition of an indole to dichlorobenzoquinone promoted by Brønsted acid, followed by a Lewis acid-pro...
Practical solid-phase parallel synthesis of Delta(5)-2-oxopiperazines via N-acyliminium ion cyclization [0.03%]
实用固相平行合成通过N-酰亚胺离子环化合成Delta(5)-2-酮哌嗪
Sung-Chan Lee,Seung Bum Park
Sung-Chan Lee
A practical solid-phase strategy for the synthesis of Delta(5)-2-oxopiperazines via N-acyliminium ion cyclization has been developed. A key step in the library synthesis is tandem acidolytic cleavage with subsequent in situ iminium formatio...