One-pot microwave-assisted synthesis of a benzopyrano[2,3-c]pyrazol-3(2H)-one library [0.03%]
一种苯并吡喃并吡唑酮化合物库的一锅微波合成法
Alexander V Borisov,Nikolay Yu Gorobets,Sergey A Yermolayev et al.
Alexander V Borisov et al.
Ionic liquid phase synthesis of tetrahydropyrano- and tetrahydrofuranoquinolines under microwave irradiation [0.03%]
微波辐射下离子液体相合成四氢吡喃酮和四氢呋喃酮类化合物
Ming Li,Entao Sun,Lirong Wen et al.
Ming Li et al.
One-pot synthesis of quinoline-based tetracycles by a tandem three-component reaction [0.03%]
三组分串联反应一锅法合成喹啉类四环化合物
Chao Che,Jing Xiang,Guo-Xin Wang et al.
Chao Che et al.
A practical one-pot synthetic strategy for the efficient synthesis of a range of structurally interesting and bioactive quinoline-based tetracycles has been developed. A key step in the synthesis is a tandem three-component reaction of hete...
96-well plate-to-plate gravity fluorous solid-phase extraction (F-SPE) for solution-phase library purification [0.03%]
用于溶液相库净化的96孔板重力式氟化固体相萃取（F-SPE）
Wei Zhang,Yimin Lu
Wei Zhang
Large particle size (125_210 microm) fluorous silica gel bonded with a -SiCH2CH2C8F17 stationary phase has been employed for gravity-driven fluorous solid-phase extraction (F-SPE) on two types of 96-well plates. A 1 or 0.75 g portion of flu...
Diversity-oriented synthesis of functionalized quinolin-2(1H)-ones via Pd-catalyzed site-selective cross-coupling reactions [0.03%]
钯催化位点选择性交叉偶联反应合成功能化喹啉-2(1H)-酮的多样性导向合成研究
Zhiyong Wang,Bing Wang,Jie Wu
Zhiyong Wang
Biologically active 3-amino-4-arylquinolin-2(1H)-ones and 3-alkenyl-4-arylquinolin-2(1H)-ones were synthesized in an efficient and concise manner, utilizing readily available 4-hydroxyquinolin-2(1H)-one as starting material. The key steps, ...
Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [I]-condensed purines [0.03%]
N7位取代嘌呤的区域选择性固相合成方法及其在8-氮杂嘌呤和稠合嘌呤中的应用
Han Fu,Mark Kheng Chuan Tan,Yulin Lam
Han Fu
A highly regioselective and traceless solid-phase route to 1,7,8-trisubstituted purines has been developed. This methodology could be extended to the preparation of 8-azapurines and [i]-condensed purines. A representative set of 17 purines,...
Jun-Seok Lee,Jae Wook Lee,Young-Tae Chang
Jun-Seok Lee
Solution-phase parallel synthesis of 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones [0.03%]
溶液相平行合成2,3-二氢-1,5-苯并噻唑епин-4(5H)-酮类化合物
Hai-Yan Zhao,Gang Liu
Hai-Yan Zhao
Practical and efficient parallel methods have been developed for the synthesis of 7,8-disubstituted 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones and 3,7,8-trisubstituted 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones. This benzothiazepin-4(5H)-one ...
Efficient solid-phase synthesis of 2-substituted-3-hydroxy-4(1H)-quinolinone-7-carboxamides with two diversity positions [0.03%]
具有两个多样性位置的2-取代-3-羟基-4(1H)-喹啉酮-7-酰胺类化合物的高效固相合成法
Miroslav Soural,Viktor Krchnák
Miroslav Soural
A highly efficient solid-phase synthesis of 2-substituted-3-hydroxy-4(1H)-quinolinone-7-carboxamides was developed using anthranilates and bromoketones as the key synthons. Primary amines immobilized to an acid-cleavable BAL linker were acy...
Ultrasonic-promoted three-component synthesis of some biologically active 1,2,5,6-tetrahydropyrimidines [0.03%]
超声波促进的生物活性1,2,5,6-四氢嘧啶的三组分合成
Elena A Muravyova,Sergey M Desenko,Vladimir I Musatov et al.
Elena A Muravyova et al.
Multicomponent reactions and organic synthesis with ultrasonic activation have been used as key methods for the synthesis of tetrahydropyrimidine derivatives. The three-component condensation of 1,3-diarylprop-2-en-1-one with ammonia and al...