When immature plasma cells form lymphoma: how to improve on diagnostics and treatment of plasmablastic lymphoma? [0.03%]
不成熟浆细胞形成淋巴瘤时：如何改进套细胞淋巴瘤的诊断和治疗？
Jorge J Castillo
Jorge J Castillo
Plasmablastic lymphoma (PBL) is a rare and aggressive, usually CD20-negative, B-cell lymphoma with features between multiple myeloma and diffuse large B-cell lymphoma. Approximately 120 new cases are diagnosed annually in the United States,...
Raj S Kasthuri
Raj S Kasthuri
Hereditary hemorrhagic telangiectasia (HHT) is an inherited vasculopathy that results in dysregulated angiogenesis leading to the development of mucocutaneous telangiectasias and visceral organ arteriovenous malformations. HHT is the second...
Update in the diagnosis of complement-mediated thrombotic microangiopathy/atypical hemolytic uremic syndrome [0.03%]
补体介导的血栓性微血管病/非典型溶血尿毒综合征诊断进展
Michael Arthur Cole
Michael Arthur Cole
Complement-mediated thrombotic microangiopathy (C-TMA), also referred to as atypical hemolytic uremic syndrome (aHUS), is a rare but severe cause of microangiopathic hemolysis and organ injury. Despite advances in understanding its pathophy...
Angela Dispenzieri
Angela Dispenzieri
POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes) syndrome is a complex paraneoplastic syndrome related to a lambda-restricted low-tumor burden neoplasm. The diagnosis must be considered in the context of what mi...
Selecting the best treatment approach and optimizing sequencing strategies in large B-cell lymphoma [0.03%]
大B细胞淋巴瘤最佳治疗选择及优化序贯策略
Gloria Iacoboni,Franck Morschhauser
Gloria Iacoboni
The advent of T-cell redirecting strategies, including chimeric antigen receptor T cells and bispecific antibodies, has significantly improved the prognosis of patients with relapsed/refractory large B-cell lymphoma. Current, ongoing clinic...
Kristine Matusiak,A Kinga Malinowski,Donald M Arnold
Kristine Matusiak
Immune thrombocytopenia (ITP) often presents for the first time in pregnancy, or, in patients with a history of ITP, pregnancy can trigger a relapse. ITP in pregnancy is often mild, leading to minimal or no symptoms; however, treatment may ...
No shots needed: direct oral anticoagulants in cancer-associated thrombosis-10-year follow-up [0.03%]
无需注射：直接口服抗凝血剂治疗癌症相关静脉血栓形成——十年随访研究
Ruchi Desai,Michael Jaglal
Ruchi Desai
Active malignancy is a known prothrombotic state, first described by Armand Trousseau as thrombophlebitis occurring in a patient with metastatic gastric cancer. The most common presentation of cancer-associated thrombosis (CAT) is venous th...
Heather A Leitch,Rena Buckstein
Heather A Leitch
The clinical benefits of iron overload (IOL) management in hereditary anemias, including organ preservation and dramatically improved overall survival (OS), are widely accepted. Adult myelodysplastic syndrome (MDS) patients are older and ma...
Iron toxicity and hematopoietic cell transplantation: do we understand why iron affects transplant outcome? [0.03%]
铁中毒和造血细胞移植：我们真的了解铁影响移植效果的原因吗？
Emanuele Angelucci
Emanuele Angelucci
In the last decades, we have witnessed huge progress in the understanding of iron metabolism and the consequences of its dysregulation in case of overload, and we have understood how, in the case of hematopoietic transplantation, the toxici...
Platton S, Sivapalaratnam S, Raheja P. Diagnosis and laboratory monitoring of acquired hemophilia A. Hematology Am Soc Hematol Educ Program. 2023;2023(1):11-18 [0.03%]
获得性血友病的诊断和实验室监测 Platton S，Sivapalaratnam S，Raheja P.
S Platton,S Sivapalaratnam,P Raheja
S Platton