Development and validation of a novel clinical decision support tool for sustained remission in Crohn's disease: a multi-center real-world study [0.03%]
一种新型临床决策支持工具在克罗恩病持续缓解中的发展与验证：一项多中心真实世界研究
Yun Qiu,Chuhan Zhang,Kang Chao et al.
Yun Qiu et al.
Background and aims: Long-term outcomes for Crohn's disease (CD) patients treated with infliximab (IFX) remain suboptimal. We developed and validated a clinical decision support tool (CDST) to predict sustained remission ...
Contraindications of steroid treatment in the setting of severe alcohol-associated hepatitis: are they absolute contraindications? [0.03%]
重症酒精性肝炎糖皮质激素治疗禁忌症：绝对禁忌吗？
Akif Altinbas,Henriette Kreimeyer,Njei Basile et al.
Akif Altinbas et al.
Background: Severe alcohol-associated hepatitis (AH) remains a major challenge in clinical practice due to its limited treatment options and high short-term mortality. Although corticosteroids have long been the mainstay ...
Malignant hilar biliary strictures: palliative drainage during end-of-life care [0.03%]
恶性肝门胆管狭窄：临终关怀期间的姑息性引流
Haytham Bayadsi,Clara-Marie Clasen,Stefan Hofmeyr et al.
Haytham Bayadsi et al.
Aims: To investigate predictive factors in patients with non-curable malignant hilar biliary obstruction (mHBO) and identify those with a life expectancy of 30 days or less, who would not benefit from palliative biliary d...
Efficacy, safety and cost-effectiveness of potassium-competitive acid blockers versus proton pump inhibitors in gastroesophageal reflux disease [0.03%]
钾竞争性酸阻滞剂与质子泵抑制剂治疗胃食管反流病的有效性、安全性和成本效益分析
Feihan Li,Jiawu Tan,Lifeng Qin
Feihan Li
Background: To evaluate the efficacy and safety of potassium-competitive acid blockers (P-CABs) versus proton pump inhibitors (PPIs) in the treatment of gastroesophageal reflux disease (GERD) through a meta-analysis, expl...
Prognosis after resection or ablation of hepatocellular carcinoma: real-world evidence from a Danish population-based cohort [0.03%]
丹麦人群队列的真实世界证据：肝细胞癌切除或消融术后的预后情况
Andreas Halgreen Eiset,Gerda Elisabeth Villadsen,Nikolaj Skou et al.
Andreas Halgreen Eiset et al.
Objectives: The real-world clinical course of hepatocellular carcinoma (HCC) remains poorly understood. We aimed to describe the prognosis of Danish patients with HCC treated with curative-intent resection or ablation str...
Investigating instruments for evaluation of gastrointestinal burdens in patients with systemic mastocytosis: an exploratory multimethod study [0.03%]
用于评估系统性肥大细胞增多症患者胃肠负担的评估工具：一项探索性多方法研究
Kerstin Hamberg Levedahl,Marie Carlson,Gunnar P Nilsson et al.
Kerstin Hamberg Levedahl et al.
Objectives: Systemic mastocytosis (SM) is a rare hematopoietic disease, in which gastrointestinal (GI) problems are common. There are no valid instruments for assessing GI problems in patients with SM. As the symptoms oft...
Serum interferon gamma-induced protein 10 in obese non-diabetic patients with metabolic dysfunction-associated steatotic liver disease [0.03%]
肥胖非糖尿病代谢紊乱相关脂肪性肝病患者的血清干扰素γ诱导蛋白10检测
Mohamed Fouad,Olfat Fawzy,Sally Abd El-Aziz et al.
Mohamed Fouad et al.
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most prevalent chronic liver disease globally, strongly linked to obesity, insulin resistance, and metabolic syndrome. Inflamma...
Association between quality of life and inflammation and fibrosis markers in primary biliary cholangitis over three-year follow-up [0.03%]
自身免疫性胆汁性肝硬化患者生活质量与炎症及纤维化标志物之间的关系三年回顾分析
Matias Hauge Böttcher,Lars Bossen,Anders Mellemkjær et al.
Matias Hauge Böttcher et al.
Patients with primary biliary cholangitis (PBC) consistently report low quality of life (QoL), but determinants of decreased QoL remain unresolved. We aimed to investigate the role of inflammation, fibrosis, and treatment response on QoL in...
High consumption of risk medication and underutilization of proton pump inhibitors among patients with upper gastrointestinal bleeding due to peptic ulcers and erosions (BLUE study) [0.03%]
消化性溃疡和糜烂所致上消化道出血患者高风险药物使用过多及质子泵抑制剂用量不足（BLUE研究）
Katrine Kauczynska Romstad,Owen Thomas,Taran Søberg et al.
Katrine Kauczynska Romstad et al.
Background: Antiplatelet and anticoagulant therapy are associated with a significant risk of upper gastrointestinal bleeding (UGIB), as is the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Concomitant treatment wi...