Serology-based diagnosis of coeliac disease in secondary care: a single-centre study in Norway [0.03%]
基于血清学的乳糜泻二级诊疗中心诊断研究：一项在挪威开展的研究
Jostein H Ibsen,Ane Kongsgaard,Michael Sovershaev et al.
Jostein H Ibsen et al.
Background: Coeliac disease (CeD) affects 1-2% of the western population. Diagnosis is based on serology and duodenal biopsy, but serology-based diagnosis in adults has been approved in Europe. ...
Liver enzyme alterations during pregnancy in IBD are not attributable to disease activity or medication [0.03%]
肝酶在炎症性肠病孕妇中的变化与疾病活动无关或不是药物所致
Dianne G Bouwknegt,Hylke C Donker,Bram van Es et al.
Dianne G Bouwknegt et al.
Background: Inflammatory bowel disease (IBD) is often diagnosed during reproductive age, requiring adequate management during pregnancy. Physiological changes during pregnancy affect liver enzymes, complicating interpreta...
Novel difficulty scoring system for endoscopic submucosal dissection in early gastric cardia cancer: multicenter Development and validation [0.03%]
早期食管胃结合部癌内镜粘膜下剥离难度评分系统创建及多中心验证研究
Zhilin Liu,Linfu Zheng,Xingjie Gao et al.
Zhilin Liu et al.
Background/aim: Endoscopic submucosal dissection (ESD) for early gastric cardiac cancer (EGCC) faces anatomical challenges. This study aims to develop and validate a predictive model for ESD difficulty in EGCC, providing ...
Prognostic value of KRAS gene mutations in pancreatic ductal adenocarcinoma: a systematic review and meta-analysis [0.03%]
KRAS基因突变在胰腺导管腺癌预后中的价值：系统评价和 Meta分析
Saeed Aslani,Belinda Lee,Andrew H Strickland et al.
Saeed Aslani et al.
Background: This meta-analysis aimed to evaluate the association between distinct KRAS mutations and overall survival (OS) in pancreatic ductal adenocarcinoma (PDAC) patients. ...
Solid food swallows of high-resolution manometry unmask esophageal hypomotility in GERD [0.03%]
高分辨率测压下固体食物吞咽提示胃食管反流病患者的食管运动减弱
Rong Rong Chen,Zhang Yu Wang,Ke Yan Wu et al.
Rong Rong Chen et al.
Aim: Gastroesophageal reflux disease (GERD) is closely linked to esophageal motility dysfunction. While high-resolution manometry (HRM) remains the gold standard for evaluating esophageal motility, the conventional single...
Inpatient and post-discharge thromboembolic events in inflammatory bowel disease patients: a 13 year retrospective cohort study at a tertiary Centre [0.03%]
溃疡性结肠炎及克罗恩病患者的住院期间和出院后的血栓事件：一项为期13年的回顾性队列研究
T Matthews,S M Connor,H Tyrrell et al.
T Matthews et al.
Objectives: Patients with inflammatory bowel disease (IBD) are at increased risk of thromboembolic events (TEEs), particularly during hospitalisation. While extended thromboprophylaxis is standard in the post-partum and t...
Genetic sucrase-isomaltase deficiency: epidemiology, clinical spectrum, and diagnostic challenge [0.03%]
遗传性蔗糖-异麦芽糖酶缺乏症的流行病学、临床特点及诊断挑战
Engin Demir,Ali Tunç,Burak Başer et al.
Engin Demir et al.
Purpose: The sucrase-isomaltase (SI) gene encodes sucrase-isomaltase enzyme found on the intestinal brush-border that has a major function in the hydrolysis of sucrose, oligosaccharides, and starch. Mutations disrupting i...
The impact of biliary drainage on chemotherapy initiation and survival in patients with non-resected perihilar cholangiocarcinoma: a population-based study in the Netherlands [0.03%]
荷兰人口-Based研究：肝门胆管癌不可切除患者胆道引流对化疗启动时间及生存率的影响分析
D M de Jong,E van Ette,L G van der Geest et al.
D M de Jong et al.
Background: Perihilar cholangiocarcinoma (pCCA) is a rare malignancy originating from the bile duct bifurcation which is often diagnosed in an advanced stage. At presentation, most patients present with jaundice requiring...
High-dose intravenous iron improves quality of life in patients with inflammatory Bowel disease and iron deficiency [0.03%]
静脉高剂量铁剂改善炎症性肠病患者的缺铁症状和生活质量
Marte Eide Jahnsen,Trond Espen Detlie,Geir Egil Eide et al.
Marte Eide Jahnsen et al.
Background: Iron deficiency is common in patients with inflammatory bowel disease (IBD) and may lead to a variety of distressing symptoms negatively impacting quality of life. ...