Simultaneous determination of mycophenolate and its metabolite mycophenolate-7-o-glucuronide with an isocratic HPLC-UV-based method in human plasma and stability evaluation [0.03%]
人血浆中霉酚酸及其代谢产物霉酚酸-7-O-葡萄糖醛酸酯的同时测定与稳定性评价的异相HPLC-UV法
Olesja Rissling,Steffen Bauer,Maria Shipkova et al.
Olesja Rissling et al.
Objectives: Mycophenolic acid (MPA) is an immunosuppressive agent which is commonly used in a fixed dose regime in solid organ transplantation. For clinical trials and therapeutic drug monitoring measuring plasma concentr...
A population-wide applicable HLA-DQ2 and DQ8 genotyping using DNA from dried blood spots and duplex allele-specific qPCR amplification [0.03%]
一种利用干血点DNA和双通道等位基因特异性qPCR扩增进行HLA-DQ2和DQ8分型的方法
Sandra Aguayo-Patrón,Lizbeth Beltrán-Sauceda,Ana María Calderón de la Barca
Sandra Aguayo-Patrón
Genotyping of HLA-DQ2 and DQ8 haplotypes is important for diagnosis or for screening of early risk detection of celiac disease or type 1 diabetes. Usually, venous blood DNA extraction and expensive and time consuming amplification are used,...
Effects of thyroid hormone withdrawal on natriuretic peptides during radioactive iodine therapy in female patients with differentiated thyroid cancer [0.03%]
甲状腺功能减退对女性分化型甲状腺癌患者放射性碘治疗期间钠尿肽的影响
Adina Elena Stanciu,Anca Elena Hurduc,Marcel Marian Stanciu
Adina Elena Stanciu
Objective: We aimed to investigate the effects of thyroid hormone withdrawal on N-terminal prohormone forms of atrial natriuretic peptide (NT-proANP) and brain natriuretic peptide (NT-proBNP) during radioiodine therapy in...
Vanja Cejvanovic,Camilla Asferg,Laura Kofoed Kjær et al.
Vanja Cejvanovic et al.
Objectives: The aim of our study was to investigate if the 24-hour excretion of the urinary markers for oxidative stress to DNA and RNA, measured as 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydro-guan...
An evaluation of multiplex bead-based analysis of cytokines and soluble proteins in archived lithium heparin plasma, EDTA plasma and serum samples [0.03%]
锂肝素血浆、EDTA血浆和血清样本中多重珠蛋白免疫测定检测细胞因子和可溶性蛋白的评估分析
Line Brøndum,Brita Singers Sørensen,Jesper Grau Eriksen et al.
Line Brøndum et al.
Objective: To assess the usability of archived plasma and serum by multiplex (Luminex) analysis of circulating proteins (analytes) by evaluating the day to day variation, the effect of several freeze-thaw cycles, and the ...
The shrunken pore syndrome is associated with declined right ventricular systolic function in a heart failure population - the HARVEST study [0.03%]
缩孔综合征与心力衰竭患者的右心室收缩功能减退有关——HARVEST研究
Anders Christensson,Anders Grubb,John Molvin et al.
Anders Christensson et al.
The close relationship between heart and kidney diseases was studied with respect to the 'Shrunken pore syndrome' that is characterized by a difference in renal filtration between cystatin C and creatinine. Patients were retrieved from the ...
Individual responses in biomarkers of health after marathon and half-marathon running: is age a factor in troponin changes? [0.03%]
马拉松和半程马拉松跑步对健康生物标志物的个体反应：肌钙蛋白的变化与年龄有关吗？
Markus Niemelä,Päivikki Kangastupa,Onni Niemelä et al.
Markus Niemelä et al.
Although strenuous physical activity is known to cause notable perturbations in blood chemistries, only few studies exist observing exercise-induced simultaneous changes in biomarkers of health status. We compared markers of muscle, cardiov...
An in-house multilocus SNP genotyping assay for evaluation of complex genetic diseases [0.03%]
一种针对复杂遗传性疾病评估的内部多位点SNP基因型检测体系
Swarup A V Shah,Altaf A Kondkar,Tester F Ashavaid
Swarup A V Shah
Background: With an increase in the discovery of newer genetic loci/polymorphisms in complex multifactorial diseases, there is also an increased need for methods that can simultaneously genotype multiple loci in a cost-ef...
Serum levels of Lp(a) are related to waist circumference in NAFLD patients with low prevalence of co-morbidities [0.03%]
血浆Lp（a）水平与低并发症非酒精性脂肪肝病患者的腰围有关
Giovanni Tarantino,Carmine Finelli,Saverio Gioa et al.
Giovanni Tarantino et al.
Background: Novel evidence suggests a relationship between circulating Lp(a) levels and the presence of cardiovascular events independently from the cardio-metabolic profile. ...
Old and new approaches to the interpretation of acid-base metabolism, starting from historical data applied to diabetic acidosis [0.03%]
历史数据在糖尿病酸中毒中的应用以及对酸碱代谢解悉的旧观点和新观点
Roberto Mioni,Alessandra Marega,Marco Lo Cicero et al.
Roberto Mioni et al.
The approach to acid-base chemistry in medicine includes several methods. Currently, the two most popular procedures are derived from Stewart's studies and from the bicarbonate/BE-based classical formulation. Another method, unfortunately l...