Identification of novel genetic variants in the mutational hotspot region 14 kb upstream of the LCT gene in a Mexican population [0.03%]
在墨西哥人群中鉴定LCT基因上游14kb热点区域的新型遗传变异体
Liliana Valencia,Andrés Randazzo,Peter Engfeldt et al.
Liliana Valencia et al.
Several polymorphic loci linked to lactase persistence (LP) have been described, all located in a small mutational hotspot region far upstream (∼14 kb) of the lactase (LCT) gene. One is typically found in Europeans, LCT -13910C > T, severa...
Internal dysregulation of the renin system in patients with stable liver cirrhosis [0.03%]
肝硬化患者肾素系统的内在失调
Annette Dam Fialla,Helle C Thiesson,Peter Bie et al.
Annette Dam Fialla et al.
Sodium retention in cirrhosis is associated with changes in the renin-angiotensin-aldosterone system (RAAS), the sympathetic nervous system (SNS), and the glomerular filtration rate (GFR). We hypothesized that in cirrhosis the acute reactio...
Kaare R Norum
Kaare R Norum
A pilot study on the applicability of thromboelastometry in detecting brain tumour-induced hypercoagulation [0.03%]
血栓弹力图检测脑肿瘤相关高凝状态的可行性研究试点工作
Erik Jansohn,Johan Bengzon,Thomas Kander et al.
Erik Jansohn et al.
Patients with intracranial tumours have an increased risk of venous thromboembolism, particularly during the first month after neurosurgery. A proposed explanation for this increased risk, are procoagulant tumour-derived substances, such as...
Miloš Žarković,Jasmina Ćirić,Biljana Beleslin et al.
Miloš Žarković et al.
Assessment of insulin sensitivity based on a single measurement of insulin and glucose, is both easy to understand and simple to perform. The tests most often used are HOMA and QUICKI. The aim of this study was to assess the biological vari...
Corrigendum [0.03%]
勘误表
Detection of subclinical vitamin K deficiency in neurosurgery with PIVKA-II [0.03%]
用PIVKA-II检测神经外科手术亚临床维生素K缺乏症
Sofia Dahlberg,Caroline Ulfsdotter Nilsson,Thomas Kander et al.
Sofia Dahlberg et al.
Vitamin K is known for supporting the carboxylation of hepatic coagulation proteins. Levels of proteins induced by vitamin K absence for factor II (PIVKA-II) reflect hypocarboxylated prothrombin and can be used to detect subclinical vitamin...
Modelling long-term evolution of chitotriosidase in non-neuronopathic Gaucher disease [0.03%]
非神经病变型戈谢病的长程胆固醇三硫酸酯酶模型化评估研究
Cristina Drugan,Tudor C Drugan,Paula Grigorescu-Sido et al.
Cristina Drugan et al.
Chitotriosidase, an enzyme secreted by activated macrophages, is widely used as a biomarker for therapeutic monitoring and patient follow-up in Gaucher disease (GD), a lysosomal disorder caused by an inherited deficiency of glucocerebrosida...
Alterations in serum levels of IL-17 in contrast to TNF-alpha correspond to disease-modifying treatment in relapsing-remitting multiple sclerosis [0.03%]
与反复发作性多发性硬化症的疾病修正治疗相对应的是IL-17而非TNF-α的血液浓度变化
Anastasiya Georgieva Trenova,Georgi Svetoslavov Slavov,Maria Georgieva Manova et al.
Anastasiya Georgieva Trenova et al.
Cytokines of different types play an important role in multiple sclerosis (MS) pathogenesis as mediators and regulators of the immune processes in the central nervous system. The aim of the study was to determine the effect of interferon-be...
White blood cell counts, insulin resistance, vitamin D levels and sarcopenia in Korean elderly men [0.03%]
韩国老年男性中的白细胞计数、胰岛素抵抗、维生素D水平和肌少症的关系
Sang-Hwan Kim,Hyun Seok Kwon,Hee-Jin Hwang
Sang-Hwan Kim
Sarcopenia is a major determinant of frailty, disability and mortality in the elderly. Whether low-grade inflammation, insulin resistance and vitamin D are independently associated with sarcopenia remains unclear. In our study, sarcopenia w...