Screening efficacy of erythroferrone and hepcidin in identifying thalassemia with iron-deficiency anemia among pregnant women [0.03%]
筛选出孕妇中合并有缺铁性贫血的地中海贫血的筛查效能：铁调素和红细胞源性铁调素的检测价值评估
Nan Huang,Jianlong Zhuang,Yufang Wang et al.
Nan Huang et al.
This study investigated the prevalence of Thalassemia (Thal) gene in pregnant women in the Quanzhou area, China. And explored the clinical application value of Erythroferrone (ERFE) and Hepcidin in screening pregnant women with Thal complic...
Identification of cystatin C as a new marker of glomerular filtration rate, and of shrunken pore syndrome - a new kidney disorder defining selective glomerular hypofiltration syndromes - calls for expansion of the international KDIGO guidelines [0.03%]
对胱抑素C进行鉴定，将其确定为新的肾小球滤过率标志物，“缩窄孔径症候群”是一种新的肾脏疾病，可定义选择性肾小球低滤过综合症，呼吁扩大国际KDIGO指南
Anna Åkesson,Carl Öberg,Linnea Malmgren et al.
Anna Åkesson et al.
Cystatin C was identified as a marker of glomerular filtration rate (GFR) in 1979, and the parallel analysis of cystatin C and creatinine led to the identification of shrunken pore syndrome (SPS) - a new kidney disorder - in 2015. Since the...
Performance comparison of Mindray EH-2090 Urinalysis analyzers and Sysmex UF-5000 [0.03%]
迈瑞EH-2090和希森美康UF-5000尿液流水线对比性能评估
Juan Chen,Chen Zhang,Qiaoping Xu et al.
Juan Chen et al.
In this study, we used manual microscopy as the gold standard, and compared the analytical and clinical performance of EH-2090 and UF-5000 to evaluate their application characteristics in daily clinical practice. Results show the EH-2090 ha...
Hb Tacoma is difficult to detect and may cause false results with different HbA1c methods [0.03%]
Hb Tacoma难以检测且可能对不同HbA1c方法产生假阳性结果
Britta Landin,Soheir Beshara,Johan Eskils et al.
Britta Landin et al.
The haemoglobin variant Hb Tacoma [HBB:c.93G > T;CD30(Arg > Ser) was detected in approximately 1 in 1000 patients tested for HbA1c at Karolinska University Hospital, Stockholm. Incidentally, five homozygous individuals were found, none of t...
Preanalytical factors of enhanced liver fibrosis (ELF™) laboratory testing: the score is affected by hemolysis [0.03%]
增强肝纤维化(ELF™)实验室检测的前分析因素：评分受溶血影响
Anni Kelkka,Christel Pussinen,Lotta Joutsi-Korhonen et al.
Anni Kelkka et al.
Liver fibrosis is a common condition that potentially leads to cirrhosis, liver dysfunction, and hepatocellular carcinoma. The Enhanced Liver Fibrosis (ELF™) test is a validated tool for assessing fibrosis. The influence of preanalytical f...
Joachim Baech,Lærke Andersen,Stine Linding Andersen
Joachim Baech
Biochemical tests are crucial in acute patient care, and the validity of the results is important. We aimed to evaluate extreme results reported in a routine hospital laboratory and to review patient characteristics. This is a retrospective...
The implication of abnormal routine coagulation parameters in Dabie bandavirus infection [0.03%]
Dabi埃立克病毒感染者凝血常规非常指标的寄义探讨
Tianzhu Zhang,Huan Bai,Bin Wang et al.
Tianzhu Zhang et al.
Prolonged activated partial thromboplastin time (APTT) and thrombin time (TT), normal prothrombin time (PT) and elevated D-dimer level are typical manifestation of routine coagulation parameters in patients infected with Dabie bandavirus (D...
Lei Zhang,Mingjian Lian,Yufan Wang et al.
Lei Zhang et al.
Objective: To explore the potential metabolic markers related to gestational hypothyroidism in early diagnosis, to find new intervention targets, and to provide metabolic pathway information for elucidating the pathogenes...
Is it necessary to request testing for antibodies against extractable nuclear antigens in case of antinuclear antibody negativity? [0.03%]
抗核抗体阴性的患者是否需要检测可提取核抗原自身抗体？
Emrah Salman,Bedia Dinç
Emrah Salman
Background: Inappropriate or unnecessary test requests are one of the reasons for the increase in laboratory utilization. We aimed to investigate the frequency of simultaneous antinuclear antibody (ANA) and extractable nu...
Arne Åsberg,Ann Elisabeth Åsberg
Arne Åsberg
In a study of the diagnostic accuracy of a quantitative biomarker, the researcher compares the concentration of the biomarker in patients with and without the disease in question. The diagnosis must be set without knowledge of the biomarker...