Rethinking repeat testing: when analytical criteria tell different stories [0.03%]
再论复查检测：当分析标准讲述不同的故事时
Özben Özden Işıklar,Evin Kocatürk,Zeynep Başoğlu et al.
Özben Özden Işıklar et al.
Background: Repeat testing in emergency clinical chemistry is common, often triggered by critical values, delta checks, or instrument flags. However, its clinical utility is uncertain, and unnecessary repeats may delay re...
Sample stability of forty-two analytes in plasma or serum pools after one to four repeated -80 °C freeze-thaw cycles [0.03%]
血浆或血清样本在-80℃反复冻融后42种组分的稳定性分析
Gustav Mikkelsen,Ketil Thorstensen,Ingrid Alsos Lian et al.
Gustav Mikkelsen et al.
Knowledge of the pre-analytical stability is crucial when using frozen biobank samples for e.g. reference intervals studies. Such samples are sometimes subjected to multiple freeze-thaw cycles before analysis. There is a lack of comprehensi...
Establishment of reference interval for platelet aggregation test with three agonists on automated haemostasis analyzers [0.03%]
三种激动剂检测血小板聚集率的参考区间建立及评价研究
Weiling Shou,Qian Chen,Chaochao Ma et al.
Weiling Shou et al.
To establish reference intervals (RIs) for the maximal aggregation rate (MA%) mainly of platelet aggregation tests induced by Collagen (COL), epinephrine (EPI), and ristocetin (RIS) using two automated haemostasis analyzers. Platelet aggreg...
Managing demand for the direct antiglobulin test with a big data-derived predictive equation [0.03%]
基于大数据的预测方程管理直接抗球蛋白试验的需求
David Ceacero-Marín,Isabel Puig-Pey Comas,Javier Nieto-Moragas et al.
David Ceacero-Marín et al.
Background: The direct antiglobulin test (DAT) is a key diagnostic tool in evaluating autoimmune haemolytic anaemia. However, indiscriminately ordering this test, together with certain methodological limitations, can comp...
Influence of pneumatic tube system transport on cell count and spectrophotometry in cerebrospinal fluid [0.03%]
运送系统对脑脊液细胞计数和分光光度法的影响
Marcus Clarin,Joel Simrén,Johanna Svanberg et al.
Marcus Clarin et al.
Pneumatic tube systems (PTS) are routinely used in many hospitals for transporting collected body fluid samples and to reduce turnaround time. However, their use for transport of CSF is not widespread, in part due to ambiguous or non-existi...
Quantitative detection of anti-centromere antibodies in primary biliary cholangitis: value of chemiluminescence immunoassay [0.03%]
抗着丝点抗体在原发性胆汁性肝硬化的量化检测：化学发光免疫法的价值评估
Yujiao Jin,Jing Wu,Shourong Liu et al.
Yujiao Jin et al.
Objective: To investigate chemiluminescence immunoassay (CLIA) in detecting anti-centromere antibodies (ACA) in primary biliary cholangitis (PBC) patients. ...
Comparison of Siemens Rapidlab 1200 blood gas analyzers and Beckman Coulter AU680 laboratory auto analyzers for sodium, potassium, hemoglobin and hematocrit parameters in emergency departments patients [0.03%]
比较西门子Rapidlab 1200血气分析仪与贝克曼库尔特AU680全自动生化分析仪检测急诊患者钠、钾、血红蛋白及血细胞比容参数的效果
Serkan Günay,Ahmet Öztürk,Arda Tuna Pakkan et al.
Serkan Günay et al.
Blood gas analyzers (BGAs) offer rapid results and operational convenience in emergency settings, whereas laboratory auto analyzers (LAAs) remain the reference standard despite slower processing. This study compared BGA and LAA measurements...
Toward accurate LDL-cholesterol estimation: platform-specific, population-based equations outperform Friedewald in two independent cohorts [0.03%]
准确估算LDL胆固醇：在两个独立队列中，特定平台、基于人群的公式优于Friedewald公式
Imola Györfi,Ion Bogdan Mănescu,Oana Roxana Oprea et al.
Imola Györfi et al.
Low-density lipoprotein cholesterol (LDL-C) remains a key biomarker for cardiovascular risk assessment. While the Friedewald equation is widely used for estimating LDL-C, its accuracy can vary across populations and analytical platforms. Th...
Redefining quality targets: a first-time application of an innovative graphic tool in hematology using six sigma [0.03%]
质量管理指标的重新定义——六西格玛在血液学中的一种图形工具的首次应用
Poongodi Rajagopal,Arundhathi S,Jyotsna Naresh Bharti et al.
Poongodi Rajagopal et al.
Hematology laboratories routinely face analytical challenges despite automation and standardized workflows. While Six Sigma metrics are increasingly applied in clinical chemistry, their use in hematology remains limited due to variability i...
Circulating NGAL as a multipurpose biomarker in patients hospitalized for acute decompensation of cirrhosis [0.03%]
肝硬化急性失代偿住院患者中循环NGAL的多用途生物标志物作用
Elayne Cristina de Morais Rateke,Camila Matiollo,Emerita Quintina de Andrade Moura et al.
Elayne Cristina de Morais Rateke et al.
There is limited evidence regarding the role of circulating neutrophil gelatinase-associated lipocalin (NGAL) in patients admitted with complications of cirrhosis. This prospective cohort study evaluated 161 adult patients hospitalized for ...