HALP score predicts 30-day readmission risk in patients with acute exacerbation of chronic obstructive pulmonary disease: a single-center retrospective study [0.03%]
HALP评分可预测慢性阻塞性肺疾病急性加重患者30天再入院风险：一项单中心回顾性研究
Bingzhen Zheng,Ru Li
Bingzhen Zheng
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide, with acute exacerbations (AECOPD) significantly contributing to disease burden and healthcare costs. This study aimed to explore the predi...
Lower serum threonine and glutamine levels could be a predictor for multiple sclerosis in pregnancy [0.03%]
妊娠期血清蛋氨酸和谷氨酰胺水平较低可能是患多发性硬化症的预测指标
Nuray Yazihan,Burcu Bozkurt Ozdal,Ayse Gulcin Bastemur et al.
Nuray Yazihan et al.
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. Recently, research has highlighted the significance of biochemical evaluation of metabolic pathways and circulating amino acids beyond their fu...
Pernille Just Vinholt,Rasmus Bank Lynggaard,Katrine Sølling Borlund Mortensen et al.
Pernille Just Vinholt et al.
Haematologists are often consulted on the need for additional diagnostic workup in patients with blast cells in peripheral blood. However, cancer risk (including solid tumors) after detection of blast cells in peripheral blood is lacking. T...
Kynurenine pathway activation in ectopic pregnancy: diagnostic value of 3-hydroxykynurenine and 3-hydroxyanthranilic acid; a prospective study [0.03%]
异位妊娠中苦马豆素途径激活的诊断价值：一项前瞻性研究中的3-羟基苦马豆素和3-羟基抗坏血酸的诊断价值分析
Sevcan Sarikaya,Fatma Sengul-Bag,Fadime Ovali et al.
Sevcan Sarikaya et al.
Background and aims: Ectopic pregnancy (EP) is a leading cause of maternal morbidity and mortality in the first trimester, accounting for nearly 9% of pregnancy-related deaths. An accurate biochemical marker for early det...
Divide or subtract: transferrin saturation versus unbound iron binding capacity (UIBC) [0.03%]
分红或减青：转铁蛋白饱和度与未结合铁的血浆容量(UIBC)
Arne Åsberg,Ann Elisabeth Åsberg,Øyvind Skadberg
Arne Åsberg
Transferrin saturation in plasma (P-TSAT) is 100 × P-iron/P-total iron binding capacity (P-TIBC). It is still used to diagnose iron deficiency, although P-ferritin is considered to be a better test. Both tests are sensitive to inflammation...
Digital droplet PCR for detection of SMN1 deletion in low-concentration fragmented cell-free DNA: a proof of concept study [0.03%]
数字液滴PCR检测低浓度片段化游离DNA样本中的SMN1基因缺失：概念验证性研究
Erhan Parıltay,Özge Güngör,Zeki Sakallı et al.
Erhan Parıltay et al.
Spinal Muscular Atrophy (SMA), an autosomal recessive neuromuscular disorder, is primarily caused by homozygous deletions in the SMN1 gene. Although multiplex ligation-dependent probe amplification (MLPA) is the gold standard for SMA diagno...
Line Philipsen,Lærke Andersen,Stine Linding Andersen
Line Philipsen
Alkaline phosphatase (ALP) is a marker of liver and bone disorders and assessment of the total ALP concentration in plasma is a commonly requested biochemical test as part of routine care. We established reference interval (RI) for total AL...
Effects of extended storage of blood samples on the results of platelet function testing: an in vitro stability study [0.03%]
血样长时间保存对血小板功能检测结果的影响：一种体外稳定性研究
Artur Hausch,Maria Deisenhammer,Nenad Mitrovic et al.
Artur Hausch et al.
In the present study, we aimed to explore the effects of extended storage of blood samples from 30 patients on the results of platelet function testing using the PFA-200 device (Collagen/EPI and Collagen/ADP tests), Multiplate instrument (A...
Magnus Dencker,Ola Björgell,Joanna Hlebowicz
Magnus Dencker
The digestion of food is known to have significant hemodynamic and metabolic effects where many have not been fully investigated. The potential effect of food intake could be interesting both from a physiological point of view and from a me...
Could the combination of fibrinogen and D-dimer improve risk assessment for acute type A aortic dissection in the emergency department? [0.03%]
纤维蛋白原与D-二聚体联合检测可改善急诊科急性A型主动脉夹层的风险评估吗？
Karl Teurneau-Hermansson,Emilia Norén,Jacob Ede et al.
Karl Teurneau-Hermansson et al.
D-dimer has been proven to be an excellent rule-out marker for acute type A aortic dissection (ATAAD) with a sensitivity exceeding 95% while specificity remains low. We hypothesized that the addition of fibrinogen, which is decreased in ATA...