Measurements of plasma melatonin by rapid lC-mS/mS enables insight into diurnal variation in healthy humans [0.03%]
通过快速LC-MS/MS测定血浆褪黑素以研究健康人的昼夜变化规律
Jakob Albrethsen,Jonas Korsgaard Andreasen,Jennifer Anton et al.
Jakob Albrethsen et al.
Measurement of plasma melatonin is important in studies of sleep disorders and neurodegenerative diseases and is also increasingly associated with cardiometabolic diseases and cancer. There is currently an increase in the usage of melatonin...
Less testing, more yield: a multicomponent intervention halves inpatient biochemistry [0.03%]
减少检测，增加收益：一项多管齐下的干预措施使入院生化检查减半
Malene S Jacobsen,Andi E Albertsen,Christian Trolle
Malene S Jacobsen
Routine inpatient biochemical testing is often repeated without clinical indication. This quality improvement project aimed to reduce low-value biochemical testing in a Danish cardiology ward, targeting a 5% reduction within 6 months and su...
Hazar Gözgöz,Tuncay Küme,Ali Necati Gökmen
Hazar Gözgöz
Blood gas analysis remains one of the most indispensable diagnostic tools in critical care, yet increasing automation often obscures its analytical foundations and limitations. This review provides an integrated perspective by tracing the e...
Recommendation on quality assurance of pneumatic transportation systems an opinion paper from the Nordic preanalytical scientific working group [0.03%]
北欧前期科学工作组关于气动管传输系统质量保证的建议-意见性论文
Jonna Pelanti,Britta Willman,Anna Linko-Parvinen et al.
Jonna Pelanti et al.
Pneumatic transportation systems (PTS) are used for sample transportation to ensure faster turn-around-times. This transportation form can however cause preanalytical changes in the samples, especially haemolysis, and it must therefore be c...
Associations between snus use and concentrations of CRP, 25(OH)D and testosterone: a population-based study [0.03%]
一种无烟烟草的使用与CRP、25(OH)D和睾丸酮浓度之间的关系：基于人口的研究
Marja Lisa Byhamre,Stefan Blankenberg,Per Dahlqvist et al.
Marja Lisa Byhamre et al.
Previous research suggests that the use of snus, a smokeless tobacco product, is associated with increased all-cause and cardiovascular mortality, but the underlying mechanisms are unknown. We aimed to evaluate the associations of snus use ...
Reference intervals for lysosomal glucocerebrosidase activity in the healthy population [0.03%]
健康人群溶酶体葡糖脑苷脂酶活性参考区间
Vinu Rajendran,Divya T Nair,Prinu Jose et al.
Vinu Rajendran et al.
Reference intervals, representing the normal range of values across age and gender groups, are essential for determining whether parameters from an individual are within physiological limits or not. Lysosomal glucocerebrosidase (GCase) acti...
The association between ionized and total magnesium in critically ill patients: a prospective cohort study [0.03%]
危重患者中离子化镁与总镁水平之间的关系：前瞻性队列研究
Eyrun A Kristinsdottir,Svajunas Statkevicius,Martin I Sigurdsson et al.
Eyrun A Kristinsdottir et al.
Most clinical laboratories measure total magnesium (tMg) which includes both the ionized (iMg) and bound forms. Only the ionized component is biologically active, and it may be influenced by acid-base status, plasma protein concentrations a...
CHI3L1 combined with Th17/Treg cells: a novel marker for the degree of HBV-related liver fibrosis [0.03%]
CHI3L1结合Th17/Treg细胞：HBV相关性肝纤维化程度的新标志物
Huiyuan Chen,Qiuying Fan,Wei Jiao et al.
Huiyuan Chen et al.
Several methods are available to differentiate non-fibrosis from advanced liver fibrosis; however, data regarding intermediate stages remain limited. A total of 246 patients with chronic hepatitis B (CHB) were enrolled and classified into f...
Interpreting two test results of one analyte from the same individual using bivariate reference values [0.03%]
应用二元参考值区间解读单个受试者同一种分析物的两项检测结果
Arne Åsberg,Gunhild Garmo Hov,Gustav Mikkelsen
Arne Åsberg
Often a measurement of an analyte is repeated in the same patient. Then the physician must interpret a pair of test results of the same analyte (x1, x2), measured in specimens collected hours to weeks apart. Physicians compare both test res...