Evaluation of the clinical, biochemical, and molecular spectrum of Cobalamin C (CblC) defect in 33 patients from Pakistan [0.03%]
巴基斯坦33例钴胺素C缺陷临床生化及分子特征分析
Sibtain Ahmed,Ling Cai,Fizza Akbar et al.
Sibtain Ahmed et al.
Background: Cobalamin C is the most common inborn error of intracellular cobalamin metabolism caused by biallelic pathogenic variants in the MMACHC gene, leading to impaired conversion of dietary vitamin B12 into its two ...
Performance evaluation of the glycated hemoglobin A1c analyzer for point-of-care testing compared with laboratory-based devices: a multicenter validation study [0.03%]
POCT糖化血红蛋白分析仪与实验室设备的对比验证研究：多中心研究
Yiwen Zhou,Fan Yang,Mi Zhou et al.
Yiwen Zhou et al.
In this dual-center study, we assessed the BioHermes A1C EXP M13 system for point-of-care (POC) HbA1c testing against two NGSP-certified HPLC instruments, the Bio-Rad D100 and Tosoh G8. Analyzing 605 samples, we evaluated the A1C EXP's repr...
Reduce energy consumption in your laboratory - switch ultra-low temperature freezers from - 80 °C to -70 °C. A pilot study on short term storage of plasma samples for coagulation testing [0.03%]
减少实验室能源消耗：将超低温冰箱从-80℃切换到-70℃。一项关于凝血检测短期储存血浆样本的试点研究
Sumangala Bhattacharya,Peter H Nissen
Sumangala Bhattacharya
It is common practice in laboratories to store biological samples in ultra-low temperature (ULT) freezers. There is growing interest in raising the temperature of ULT freezers in order to save energy and reduce expenses, as energy conservat...
High-sensitive troponin T, suPAR and Beta-2-microglobulin changes in concentration during hemodialysis [0.03%]
高强度心肌抑制因子特异性血清肌钙蛋白T、suPAR和Beta-2-微球蛋白在血液透析过程中的浓度变化
Jan D Kampmann,Michael M Hunderup,Eva R Brix Petersen et al.
Jan D Kampmann et al.
Hemodialysis (HD) patients are at high risk of cardiovascular disease and death. Reliable biomarkers for risk stratification and detection of acute myocardial infarction (AMI) are therefore pivotal. Cardiac troponins (cTn) are the preferred...
Circulating soluble CD163 is associated with reduced Glasgow Coma Scale Score and 1-year all-cause mortality in traumatized patients [0.03%]
循环可溶性CD163与创伤患者的格拉斯哥昏迷评分降低和1年全因死亡率的关系
Signe H Hymøller,Ida A Kaaber,Maj Lesbo et al.
Signe H Hymøller et al.
Soluble CD163 (sCD163) is a biomarker of macrophage activation, not previously investigated in the circulation of traumatized patients. A biobank of 398 adult trauma patients was analyzed. Patients with an Injury Severity Score (ISS) >8 ser...
Diurnal fluctuations in biochemical parameters related to calcium homeostasis - the Bispebjerg study of diurnal variations [0.03%]
钙稳态相关生化指标的日间变化——比斯彼堡研究所关于日间变异的研究
Silje J Borge,Henriette P Sennels,Peter Schwarz et al.
Silje J Borge et al.
Purpose: This aim of this study was to assess the possible association between diurnal oscillations and biochemical markers associated with calcium homeostasis. This included the markers parathyroid hormone (PTH), total c...
Adjustment of lactate dehydrogenase concentration results according to the haemolysis index following in vitro haemolysis [0.03%]
根据体外溶血后的溶血指数调整乳酸脱氢酶浓度检测结果
Claudio Ilardo,Guillaume Coulon,Amandine Lancien et al.
Claudio Ilardo et al.
In the presence of haemolysis, the interpretation of the Lactate dehydrogenase (LDH) activity result is a major operational challenge for medical laboratories: if the origin is intravascular, then the measurement will reflect the clinical r...
Kasper Krogh Nielsen,Claus Vinter Bødker Hviid,Aase Handberg et al.
Kasper Krogh Nielsen et al.
Head injury is a potentially lethal and frequently occurring condition in the emergency department (ED). Reliable and fast diagnosis is important both for patients and flow in the ED. Circulating S100B is used to rule out the need for head ...
Retrospective study investigating the performance of the SQA-vision analyser compared with manual semen analysis [0.03%]
回顾性研究调查SQA-vision分析仪与手动精液分析性能的情况
Claudio Ilardo,Naomi Defort,Anna Gala et al.
Claudio Ilardo et al.
The objective of this study was to compare the results of semen analysis using the manual method and the SQA-Vision sperm analyser after four years of practice and with a large cohort of patients. This was a comparative study of 1130 cases ...
Establishing reference intervals for thiamine pyrophosphate and pyridoxal 5'-phosphate in whole blood in a Danish cohort using liquid chromatography tandem-mass spectrometry (LC-ms/ms) [0.03%]
采用液相色谱-串联质谱法（LC-MS/MS）在丹麦人群中建立全血焦磷酸硫胺素和吡哆醛5'-磷酸参考区间
Nicoline Munch Stidsen,Lise Nørkjær Bjerg,Birgitte Sandfeld-Paulsen
Nicoline Munch Stidsen
Vitamin B1 (thiamine pyrophosphate (TPP)) and B6 (pyridoxal 5'- phosphate (PLP)) deficiencies pose significant health risks. The current measurement method employs High-Performance Liquid Chromatography (HPLC), though, Liquid Chromatography...