Stability of 17 endocrine analytes in serum or plasma after four cycles of repeated freezing and thawing [0.03%]
血清或血浆经四个循环的反复冻融后17种内分泌分析物的稳定性
Elisabet Tjernvoll,Arne Åsberg,Ingrid Alsos Lian et al.
Elisabet Tjernvoll et al.
Publications of systematic studies on analyte stability after repeated freezing and thawing of samples are rare. We examined the stability of 17 endocrine analytes in pooled serum and/or EDTA plasma after one to four cycles of repeated free...
Evaluation of hemolysis as a source of interference in the determination of S-100B using the LIAISON® S100 assay [0.03%]
评估溶血对使用LIAISON S100测定S-100B干扰的来源评价
Jaime I Sainz de Medrano,Judit Julian,Irene Martínez et al.
Jaime I Sainz de Medrano et al.
Ceylan Bal,Esra Özyurt,Gülsen Yılmaz
Ceylan Bal
Capillary blood is often used for dried blood spot samples in metabolic screening tests. This study's objective is to examine the amino acid and acylcarnitine levels in the commonly used sampling types from the same subjects and compare the...
The effects of storage conditions on the stability of salivary melatonin in synthetic fiber swabs for home sampling [0.03%]
储存条件对家用采样棉签中唾液褪黑素稳定性的影响研究
Jennifer Anton,Charlotte S Larsen,Majken Gudmundsson et al.
Jennifer Anton et al.
Home sampling of saliva is noninvasive, easy, and convenient, especially for multiple sampling. Such samples are therefore appropriate for the measurement of melatonin, a biomarker for circadian dysregulation. However, home sampling is rest...
Evaluation of measurement uncertainty in direct and estimated serum osmolality according to ISO/TS 20914: implications for clinical diagnostics [0.03%]
ISO/TS 20914测定直接法和估计法测量血清渗透压的不确定度评定及临床意义
Mehmet Fatih Alpdemir,Sezen Tutar,Medine Alpdemir
Mehmet Fatih Alpdemir
This study examines the measurement uncertainties (MU) associated with osmolality (OSM), a crucial parameter in clinical diagnostics and treatment. The research compares the uncertainties of directly measured osmolality (dOSM) with those of...
Cold activation in PT-INR samples - Myth or reality in the modern laboratory? [0.03%]
PT-INR样本的冷激现象-现代实验室中的神话还是现实？
Annika Petersson,Karin Strandberg,Magnus Magnusson et al.
Annika Petersson et al.
Guidelines on storage for samples intended for Prothrombin Time - International Normalized Ratio (PT-INR) analysis have changed over time, sometimes advising against cold storage due to presumed cold activation of the coagulation cascade. P...
Three new tools to diagnose B12 deficiency: eGFR-adjusted methylmalonic acid (MMA100), a bivariate reference area for MMA100 and cobalamin, and a cobalamin deficiency index [0.03%]
诊断维生素B12缺乏的三种新工具：eGFR调整后的甲基马尿酸（MMA100）、MMA100和钴胺的双变量参考区域以及钴胺缺乏指数
Arne Åsberg,Gustav Mikkelsen,Ingrid Alsos Lian
Arne Åsberg
Vitamin B12 (s-cobalamin) and methylmalonic acid (s-MMA) are often interpreted together to diagnose cobalamin deficiency, in context with patient symptomatology, which is many cases is unspecific. Today, clinicians assess test results in re...
A deep dive into four thyroglobulin immunoassays from analytical perspective [0.03%]
四种甲状腺球蛋白免疫分析法的深入解析视角研究
Tuba Saadet Deveci Bulut,Muhittin Abdulkadir Serdar,Mehmet Muhittin Yalçın et al.
Tuba Saadet Deveci Bulut et al.
Backgrounds: Serum thyroglobulin immunometric assays (sTg) are crucial for monitoring differentiated thyroid cancer (DTC) treatment. However, challenges such as anti-thyroglobulin autoantibodies (TgAb) and assay variabili...
The predictive value of postoperative soluble urokinase plasminogen activator receptor concentration for postoperative complications following valvular surgery [0.03%]
瓣膜手术后术后尿激酶型纤溶酶原激活物受体可溶性浓度预测术后并发症的价值
Clara Erixon,Louise Thelaus,Emilia Johannesson et al.
Clara Erixon et al.
Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory marker that has been shown to predict poorer outcomes in cardiovascular disease and after cardiac surgery. The relationship between suPAR concentrations and postope...
Reference intervals for holotranscobalamin and total vitamin B12 in 6-12-year-old children in Norway: the Health Oriented Pedagogical Project (HOPP) [0.03%]
挪威6-12岁儿童全转钴胺素和总维生素B12的参考区间：“以健康为导向的教育项目”（HOPP）研究
Martin Frank Strand,Helle Borgstrøm Hager,Per Morten Fredriksen et al.
Martin Frank Strand et al.
Vitamin B12 (B12) is essential for DNA synthesis in all cells and for the development and maintenance of a healthy nervous system. B12 is transported in the circulation bound to two carrier proteins, haptocorrin and transcobalamin, measured...