Dysregulation of chromatin organization in pediatric and adult brain tumors: oncoepigenomic contributions to tumorigenesis and cancer stem cell properties [0.03%]
儿童和成人脑肿瘤中染色质组织调控失常：致癌表观遗传学对肿瘤发生及癌症干细胞特性的影响
Seungil Paik,Francesca Maule,Marco Gallo
Seungil Paik
The three-dimensional (3D) organization of the genome is a crucial enabler of cell fate, identity, and function. In this review, we will focus on the emerging role of altered 3D genome organization in the etiology of disease, with a special...
Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association [0.03%]
过表达的Gliotactin通过干扰Tkv-Dad关联来激活BMP信号传导
Zohreh Sharifkhodaei,Vanessa J Auld
Zohreh Sharifkhodaei
Epithelial junctions ensure cell-cell adhesion and establish permeability barriers between cells. At the corners of epithelia, the tricellular junction (TCJ) is formed by three adjacent epithelial cells and generates a functional barrier. I...
Identification of enhancers that drive the spatially restricted expression of Vsx1 and Rx in the outer proliferation center of the developing Drosophila optic lobe [0.03%]
识别驱动发育中的黑腹果蝇视叶外增殖中心Vsx1和Rx空间限制表达的增强子
Ishrat Maliha Islam,June Ng,Priscilla Valentino et al.
Ishrat Maliha Islam et al.
Combinatorial spatial and temporal patterning of stem cells is a powerful mechanism for the generation of neural diversity in insect and vertebrate nervous systems. In the developing Drosophila medulla, the neural stem cells of the outer pr...
Identification and expression analysis of chloroplast ribonucleoproteins (cpRNPs) in Arabidopsis and rice [0.03%]
阿拉伯芥和水稻叶绿体核糖核蛋白（cpRNPs）的识别与表达分析
Jiawen Wu,Huimin Liu,Shan Lu et al.
Jiawen Wu et al.
Chloroplast ribonucleoproteins (cpRNPs) are implicated in splicing, editing, and stability control of chloroplast RNAs as well as in regulating development and stress tolerance. To facilitate a comprehensive understanding of their functions...
Gut microbiome-mediated epigenetic regulation of brain disorder and application of machine learning for multi-omics data analysis [0.03%]
肠道微生物介导的脑部疾病表观遗传调控及机器学习在多组学数据分析中的应用
Harpreet Kaur,Yuvraj Singh,Surjeet Singh et al.
Harpreet Kaur et al.
The gut-brain axis (GBA) is a biochemical link that connects the central nervous system (CNS) and enteric nervous system (ENS). Clinical and experimental evidence suggests gut microbiota as a key regulator of the GBA. Microbes living in the...
Fast-GBS v2.0: an analysis toolkit for genotyping-by-sequencing data [0.03%]
快速GBS 2.0版本：一种用于基因分型测序数据的分析工具
Davoud Torkamaneh,Jérôme Laroche,François Belzile
Davoud Torkamaneh
Genotyping-by-sequencing (GBS) is a rapid, flexible, low-cost, and robust genotyping method that simultaneously discovers variants and calls genotypes within a broad range of samples. These characteristics make GBS an excellent tool for man...
Generation and molecular marker and cytological characterization of wheat - Secale strictum subsp . anatolicum derivatives [0.03%]
小麦和硬牧草亚种anatolicum衍生物的产生及分子标记和细胞学特征分析
Amit Kumar Singh,Peng Zhang,Chongmei Dong et al.
Amit Kumar Singh et al.
Cereal rye and its wild forms are important sources of genetic diversity for wheat breeding due to their resistances to biotic and abiotic stresses. Secale strictum subsp. anatolicum (Boiss.) K. Hammer (SSA) is a weedy relative of cultivate...
First DNA sequence reference library for mammals and plants of the Eastern Mediterranean Region [0.03%]
东地中海地区哺乳动物和植物的首个DNA序列参考库
Liliane Boukhdoud,Carole Saliba,Lillian D Parker et al.
Liliane Boukhdoud et al.
The Mediterranean region is identified as one of the world's 36 biodiversity hotspots, with the Earth's most biologically rich yet threatened areas. Lebanon is a hub for Eastern Mediterranean Region (EMR) biodiversity with 9116 characterize...
Transcriptional responses to water stress and recovery in a drought-tolerant fescue wild grass (Festuca ovina; Poaceae) [0.03%]
耐旱雀麦野草(Festuca ovina；禾本科)对水分胁迫和恢复的转录反应
Fan Qiu,Seton Bachle,Ryan Estes et al.
Fan Qiu et al.
Water stress associated with drought-like conditions is a major factor limiting plant growth and impacts productivity of natural plant communities and agricultural crops. Molecular responses of plants to water stress have been studied most ...
Transcriptome-wide identification, characterization, and phylogenomic analysis of cytochrome P450s from Nothapodytes nimmoniana reveal candidate genes involved in the camptothecin biosynthetic pathway [0.03%]
诺氏紫葳中细胞色素P450的转录组范围鉴定、特征分析和系统基因组分析揭示了诺利紫葳碱生物合成途径中的候选基因
Rucha C Godbole,Anupama A Pable,Vitthal T Barvkar
Rucha C Godbole
The plant Nothapodytes nimmoniana is an important source of camptothecin (CPT), an anticancer compound widely used in the treatment of colorectal, lung, and ovarian cancers. CPT is biosynthesized by the combination of the seco-iridoid and i...