Mathew W Wright,Elspeth A Bruford
Mathew W Wright
Previously, the majority of the human genome was thought to be 'junk' DNA with no functional purpose. Over the past decade, the field of RNA research has rapidly expanded, with a concomitant increase in the number of non-protein coding RNA ...
Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children [0.03%]
染色体2、8和15上的祖先特异性遗传标志与儿童胰岛素相关性状的种族差异有关
Yann C Klimentidis,Jasmin Divers,Krista Casazza et al.
Yann C Klimentidis et al.
Type 2 diabetes represents an increasing health burden. Its prevalence is rising among younger age groups and differs among racial/ethnic groups. Little is known about its genetic basis, including whether there is a genetic basis for racial...
A useful tool for drug interaction evaluation: the University of Washington Metabolism and Transport Drug Interaction Database [0.03%]
一个很有用的药物相互作用评价工具：UW药品代谢与转运相互作用数据库
Houda Hachad,Isabelle Ragueneau-Majlessi,René H Levy
Houda Hachad
The Metabolism and Transport Drug Interaction Database (http://www.druginteractioninfo.org) is a web-based research and analysis tool developed in the Department of Pharmaceutics at the University of Washington. The database has the largest...
Dexiang Gao,Jihye Kim,Hyunmin Kim et al.
Dexiang Gao et al.
High-throughput RNA sequencing is rapidly emerging as a favourite method for gene expression studies. We review three software packages - edgeR, DEGseq and baySeq - from Bioconductor http://bioconductor.org for analysing RNA-sequencing data...
Evolutionary divergence and functions of the human interleukin (IL) gene family [0.03%]
人类白细胞介素(IL)基因家族的进化分化和功能研究
Chad Brocker,David Thompson,Akiko Matsumoto et al.
Chad Brocker et al.
Cytokines play a very important role in nearly all aspects of inflammation and immunity. The term 'interleukin' (IL) has been used to describe a group of cytokines with complex immunomodulatory functions - including cell proliferation, matu...
What the papers say: text mining for genomics and systems biology [0.03%]
论文学术观点挖掘：基因组学与系统生物学中的文本数据挖掘
Nathan Harmston,Wendy Filsell,Michael P H Stumpf
Nathan Harmston
Keeping up with the rapidly growing literature has become virtually impossible for most scientists. This can have dire consequences. First, we may waste research time and resources on reinventing the wheel simply because we can no longer ma...
Analysing breast cancer microarrays from African Americans using shrinkage-based discriminant analysis [0.03%]
利用收缩判别分析法分析非洲裔美国人乳腺癌数据集
Herbert Pang,Keita Ebisu,Emi Watanabe et al.
Herbert Pang et al.
Breast cancer tumours among African Americans are usually more aggressive than those found in Caucasian populations. African-American patients with breast cancer also have higher mortality rates than Caucasian women. A better understanding ...
Comparative Study
Human genomics. 2010 Oct;5(1):5-16. DOI:10.1186/1479-7364-5-1-5 2010
Prospects for the automated extraction of mutation data from the scientific literature [0.03%]
从科学文献中自动提取突变数据的前景分析
Peter D Stenson,David N Cooper
Peter D Stenson
Duncan C Thomas,David V Conti,James Baurley et al.
Duncan C Thomas et al.
Candidate gene studies are generally motivated by some form of pathway reasoning in the selection of genes to be studied, but seldom has the logic of the approach been carried through to the analysis. Marginal effects of polymorphisms in th...
ArrayTrack: a free FDA bioinformatics tool to support emerging biomedical research--an update [0.03%]
ArrayTrack：一个免费的美国食品药品监督管理局生物信息学工具促进新兴医学研究——更新版
Joshua Xu,Reagan Kelly,Hong Fang et al.
Joshua Xu et al.
ArrayTrack is a Food and Drug Administration (FDA) bioinformatics tool that has been widely adopted by the research community for genomics studies. It provides an integrated environment for microarray data management, analysis and interpret...