Antithrombin III (AT) and recombinant tissue plasminogen activator (R-TPA) used singly and in combination versus supportive care for treatment of endotoxin-induced disseminated intravascular coagulation (DIC) in the neonatal pig [0.03%]
抗凝血酶Ⅲ和重组组织型纤溶酶原活化剂单用及合用与单纯支持疗法治疗新生猪内毒素诱导的播散性血管内凝血的比较研究
Rachel Davis-Jackson,Hernan Correa,Ronald Horswell et al.
Rachel Davis-Jackson et al.
Background: Disseminated intravascular coagulation (DIC) is a pathological disturbance of the complex balance between coagulation and anticoagulation that is precipitated by vascular injury, acidosis, endotoxin release an...
Oral heparin: status review [0.03%]
口服肝素:现状评论
Ehud Arbit,Michael Goldberg,Isabel Gomez-Orellana et al.
Ehud Arbit et al.
Unfractionated heparin and low molecular weight heparin are the most commonly used antithrombotic and thromboprophylactic agents in hospital practice. Extended out-of-hospital treatment is inconvenient in that these agents must be administe...
Thrombin generation by activated factor VII on platelet activated by different agonists. Extending the cell-based model of hemostasis [0.03%]
由不同激动剂激活的血小板上活化因子VII引发的凝血酶生成。扩展基于细胞的止血模型
Raul Altman,Alejandra Silvia Scazziota,Maria de Lourdes Herrera et al.
Raul Altman et al.
Background: Platelet activation is crucial in normal hemostasis. Using a clotting system free of external tissue factor, we investigated whether activated Factor VII in combination with platelet agonists increased thrombi...
Recent acquisitions in the pathophysiology, diagnosis and treatment of disseminated intravascular coagulation [0.03%]
近年弥散性血管内凝血病理生理、诊断和治疗学进展
Massimo Franchini,Giuseppe Lippi,Franco Manzato
Massimo Franchini
Disseminated intravascular coagulation (DIC) is a disorder characterized by both acute generalized, widespread activation of coagulation, which results in thrombotic complications due to the intravascular formation of fibrin, and diffuse he...
Detection and quantification of lupus anticoagulants in plasma from heparin treated patients, using addition of polybrene [0.03%]
聚乙二醇硫酸胆碱用于抗磷脂抗体综合征患者的狼疮抗凝血因子的检测与鉴定
Eva M Jacobsen,Elin J Trettenes,Finn Wisløff et al.
Eva M Jacobsen et al.
Background: Lupus anticoagulants prolong clotting times in phospholipid-dependent coagulation tests. Lupus Ratio assays are integrated tests for lupus anticoagulants that may be based on APTT, RVVT or dPT clotting times. ...
Giuseppe Lippi,Alessandro Volpe,Paola Caramaschi et al.
Giuseppe Lippi et al.
Background: Systemic sclerosis (SSc) is an autoimmune disorder of the connective tissue characterized by widespread vascular lesions and fibrosis. Little is known so far on the activation of the hemostatic and fibrinolyti...
Ineffective off-label use of recombinant activated factor VII in a case of bone-marrow transplantation-related gastrointestinal bleeding [0.03%]
造血干细胞移植相关胃肠出血使用重组活化因子无效的一例报告
P Eller,C Pechlaner,Cj Wiedermann
P Eller
Background: For patients with a normal coagulation system, who experience serious bleeding, sound evidence for recombinant activated factor VII (rFVIIa) as an effective haemostatic agent is only scarcely available so far ...
Socio economic crisis and mortality. Epidemiological testimony of the financial collapse of Argentina [0.03%]
经济社会危机与死亡率。阿根廷经济崩溃的流行病学证据
Enrique P Gurfinkel,Gerardo E Bozovich,Omar Dabbous et al.
Enrique P Gurfinkel et al.
Background: Natural disasters, war, and terrorist attacks, have been linked to cardiac mortality. We sought to investigate whether a major financial crisis may impact on the medical management and outcomes of acute corona...
Systemic coagulation parameters in mice after treatment with vascular targeting agents [0.03%]
血管靶向药物治疗后小鼠凝血系统的改变参数研究
Maike Unruh,Andrea Grunow,Claudia Gottstein
Maike Unruh
Background: Vascular targeting of malignant tumors has become a clinically validated new treatment approach with clear patient benefit. However clinical studies have also revealed that some types of vascular targeting age...
Anticoagulant treatment at a specialized outpatient anticoagulant therapy unit, a descriptive study [0.03%]
抗凝治疗的门诊描述性研究
Kim Ekblom,Johan Hultdin,Bo Carlberg et al.
Kim Ekblom et al.
Background: The indications for continuous oral anticoagulant treatment, the target interval and the procedures for withdrawing treatment have changed in the last 10 years. ...