Outcomes of thromboprophylaxis with enoxaparin vs. unfractionated heparin in medical inpatients [0.03%]
依诺肝素与未分级肝素预防内科住院患者血栓形成的预后比较
Lisa J McGarry,Michael E Stokes,David Thompson
Lisa J McGarry
Background: Clinical trials have shown low-molecular weight heparin (LMWH) to be at least as safe and efficacious as unfractionated heparin (UFH) for preventing venous thromboembolism (VTE) in acutely-ill medical inpatien...
The screening power of methylenetetrahydrofolate reductase C677T polymorphism versus plasma homocysteine concentration in patients with stenosis of the internal carotid artery [0.03%]
内颈动脉狭窄患者亚甲基四氢叶酸还原酶C677T基因多态性和血浆同型半胱氨酸浓度的筛选价值比较研究
Robert Loncar,Barbara T Müller,Reiner B Zotz et al.
Robert Loncar et al.
Background: Hyperhomocysteinemia is an important and independent risk factor for vascular disease. About 35% of patients with stroke and 47% of patients with peripheral arterial disease have elevated plasma homocysteine (...
Hereditary thrombophilia [0.03%]
遗传性高凝状态
Salwa Khan,Joseph D Dickerman
Salwa Khan
Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic events during infancy and childhood are increasingly recognized as a significant source of mortality and morbidity. The predisposition to form clots ...
Development of an in vitro model to study clot lysis activity of thrombolytic drugs [0.03%]
体外模型的开发以研究溶栓药物的溶解血栓作用
Sweta Prasad,Rajpal S Kashyap,Jayant Y Deopujari et al.
Sweta Prasad et al.
Background: Thrombolytic drugs are widely used for the management of cerebral venous sinus thrombosis patients. Several in vitro models have been developed to study clot lytic activity of thrombolytic drugs, but all of th...
Low dose endotoxin priming is accountable for coagulation abnormalities and organ damage observed in the Shwartzman reaction. A comparison between a single-dose endotoxemia model and a double-hit endotoxin-induced Shwartzman reaction [0.03%]
低剂量内毒素处理可导致Shwartzman反应中观察到的凝血异常和脏器损害：单次内毒素模型与二次打击内毒素诱导的Schwartzman反应的比较研究
Sjoukje H Slofstra,Hugo ten Cate,C Arnold Spek
Sjoukje H Slofstra
The clinical response of sepsis to a systemic inflammatory infection may be complicated by disseminated intravascular coagulation or DIC. In order to experimentally study the syndrome of DIC, we aimed for a severe sepsis model complicated b...
Soluble fibrin inhibits monocyte adherence and cytotoxicity against tumor cells: implications for cancer metastasis [0.03%]
可溶性纤维蛋白抑制单核细胞黏附和对肿瘤细胞的细胞毒性：对癌症转移的意义
John P Biggerstaff,Brandy Weidow,Jacqueline Vidosh et al.
John P Biggerstaff et al.
Background: Soluble fibrin (sFn) is a marker for disseminated intravascular coagulation and may have prognostic significance, especially in metastasis. However, a role for sFn in the etiology of metastatic cancer growth h...
Acquired activated protein C resistance and thrombosis in multiple myeloma patients [0.03%]
多发性骨髓瘤患者的获得性活化蛋白C抵抗和血栓形成
Víctor Hugo Jiménez-Zepeda,Virginia Jeanet Domínguez-Martínez
Víctor Hugo Jiménez-Zepeda
Background: An increased incidence of deep venous thrombosis (DVT) has been described in multiple myeloma (MM). A recently described mechanism of hypercoagulability in cancer patients including MM patients is acquired act...
Comparison of platelet function between sedentary individuals and competitive athletes at rest [0.03%]
久坐者和竞技运动员静息血小板功能的比较研究
Giuseppe Lippi,Martina Montagnana,Gian Luca Salvagno et al.
Giuseppe Lippi et al.
Background: There are controversial evidences on the effect of different types and workloads of physical exercise on primary hemostasis. In particular, little is known on the chronic influence of a strenuous and regular a...
Haemostasis, inflammation and renal function following exercise in patients with intermittent claudication on statin and aspirin therapy [0.03%]
他汀和阿司匹林治疗间歇性跛行患者运动后的止血、炎症与肾功能反应
Patrick Collins,Isobel Ford,Bernard Croal et al.
Patrick Collins et al.
Background: Previous studies have suggested that exercise in patients with intermittent claudication (IC) may induce a systemic thrombo-inflammatory response. The effect of secondary prevention therapy on this response is...
An update on prevention of venous thromboembolism in hospitalized acutely ill medical patients [0.03%]
住院内科患者的静脉血栓栓塞预防最新研究进展
Meyer Michel Samama,Franz-Xaver Kleber
Meyer Michel Samama
Both the recently updated consensus guidelines published by the American College of Chest Physicians, and the International Union of Angiology recommend thromboprophylaxis with either low-molecular-weight heparin (LMWH) or unfractionated he...