HLA-A and HLA-DRB1 may play a unique role in ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis [0.03%]
人类白细胞抗原-A和-DRB1可能在卵巢畸胎瘤相关抗N-甲基-D天冬氨酸受体脑炎中起独特作用
Xiaoya Zhao,Juan Li,Qian Zhu et al.
Xiaoya Zhao et al.
Background: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis (NMDAR-E) is a severe autoimmune neurological disorder, and the influence of teratoma-induced autoantibodies on the pathogenesis rema...
Developmental programming: gestational testosterone excess disrupts LH secretion in the female sheep fetus [0.03%]
发育编程:妊娠期睾酮过多会破坏母羊胎儿的黄体生成素分泌
Renata S M Landers,Vasantha Padmanabhan,Rodolfo C Cardoso
Renata S M Landers
Background: Prenatal testosterone (T) excess results in reproductive and metabolic perturbations in female sheep that closely recapitulate those seen in women with polycystic ovary syndrome (PCOS). At the neuroendocrine l...
Biogenesis and functions of circular RNAs and their role in diseases of the female reproductive system [0.03%]
圆形RNA的生物发生、功能及其在女性生殖系统疾病中的作用
Yalan Ma,Ying Xu,Jingshun Zhang et al.
Yalan Ma et al.
A member of the newly discovered RNA family, circular RNA (circRNA) is considered as the intermediate product of by-product splicing or abnormal RNA splicing. With the development of RNA sequencing, circRNA has recently drawn research inter...
The COVID-19 pandemic through eyes of a NYC fertility center: a unique learning experience with often unexpected results [0.03%]
新冠疫情下的纽约市生育中心:独特而常常意外的学习体验
Norbert Gleicher
Norbert Gleicher
Affecting basic tenets of human existence such as health, economic as well as personal security and, of course, reproduction, the COVID-19 pandemic transcended medical specialties and professional disciplines. Yet, six months into the pande...
Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility [0.03%]
长非编码RNA(lncRNA)在精子发生和男性不育中的作用
Meghali Joshi,Singh Rajender
Meghali Joshi
Background: Long non-coding RNAs (lncRNAs) have a size of more than 200 bp and are known to regulate a host of crucial cellular processes like proliferation, differentiation and apoptosis by regulating gene expression. Wh...
The best execution of the DuoStim strategy (double stimulation in the follicular and luteal phase of the same ovarian cycle) in patients who are poor ovarian responders [0.03%]
双刺激方案(DuoStim)在卵巢反应不良患者中的最佳实施(同一卵巢周期的卵泡期和黄体期双重刺激)
Yanqun Luo,Li Sun,Mei Dong et al.
Yanqun Luo et al.
Background: Patients found to be poor ovarian responders (POR) are a challenging patient population for any assisted reproduction technology. Despite attempts at various controlled ovarian stimulation schemes, reproductiv...
Review of psychological stress on oocyte and early embryonic development in female mice [0.03%]
心理压力对雌性小鼠卵母细胞和早期胚胎发育影响的研究进展
Qiu-Yue Zhai,Jun-Jie Wang,Yu Tian et al.
Qiu-Yue Zhai et al.
Psychological stress can cause adverse health effects in animals and humans. Accumulating evidence suggests that psychological stress in female mice is associated with ovarian developmental abnormalities accompanied by follicle and oocyte d...
Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways [0.03%]
环孢素A通过抑制p53和JNK / p38信号通路保护 Jeg-3细胞免受氧化应激诱导的凋亡
Bin He,Qi Yue Li,Yuan Yuan Wu et al.
Bin He et al.
Background: Trophoblast cells are required for the establishment of pregnancy and fetal development. Apoptosis is an essential feature for trophoblast invasion. Uncontrolled trophoblast apoptosis is related to some compli...
Sphingosine 1-phosphate protects against radiation-induced ovarian injury in female rats-impact on mitochondrial-related genes [0.03%]
鞘氨醇1-磷酸通过影响与线粒体相关的基因对雌性大鼠的辐射诱导卵巢损伤起到保护作用
Jiahui Zhao,Shuyun Zhang,Liesong Chen et al.
Jiahui Zhao et al.
The toxic effects of ionizing radiation on the gonads have been widely recognized. Sphingosine 1-phosphate (S1P) has a protective effect on ovarian injury, and although it is known that mitochondria are involved in this process, the specifi...
Raoul Orvieto,Chen Shimon,Shlomit Rienstein et al.
Raoul Orvieto et al.
Human embryogenesis frequently coinciding with cell division mistakes contributing to pervasive embryonic aneuploidy/mosaicism. While embryo self-correction was elegantly demonstrated in mouse models, human studies are lacking. Here we are ...