Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells [0.03%]
单核苷酸多态性rs2294008错义等位基因削弱了前列腺干细胞抗原在胆囊癌细胞中的抑瘤作用
Hiroe Ono,Dai Chihara,Fumiko Chiwaki et al.
Hiroe Ono et al.
Background: Prostate stem cell antigen (PSCA), an organ-dependent tumor suppressor, is down regulated in gallbladder cancer (GBC). It is anticipated that the missense allele C of the single nucleotide polymorphism (SNP) r...
Sangeetha Subramaniam,Ram Krishna Thakur,Vinod Kumar Yadav et al.
Sangeetha Subramaniam et al.
Lung cancer is one of the deadliest cancers worldwide, with the highest incidence and mortality amongst all cancers. While the prognosis of lung cancer is generally grim, with 5-year survival rates of only 15%, there is hope, and evidence, ...
Lung cancer screening update [0.03%]
肺癌筛查最新进展
Samjot Singh Dhillon,Gregory Loewen,Vijayvel Jayaprakash et al.
Samjot Singh Dhillon et al.
Lung cancer is the leading cause of cancer-related mortality globally and the American cancer society estimates approximately 226,160 new cases and 160,340 deaths from lung cancer in the USA in the year 2012. The majority of lung cancers ar...
Nicotine and lung cancer [0.03%]
尼古丁与肺癌的关系
Graham W Warren,Anurag K Singh
Graham W Warren
Tobacco use in cancer patients is associated with increased cancer treatment failure and decreased survival. Nicotine is one of over 7,000 compounds in tobacco smoke and nicotine is the principal chemical associated with addiction. The purp...
Mark W Hennon,Sai Yendamuri
Mark W Hennon
The last few years have witnessed an explosion of the use of minimally invasive techniques for the detection, diagnosis, and treatment of all stages of lung Cancer. The use of these techniques has improved the risk-benefit ratio of surgery ...
Hope for progress after 40 years of futility? Novel approaches in the treatment of advanced stage III and IV non-small-cell-lung cancer: Stereotactic body radiation therapy, mediastinal lymphadenectomy, and novel systemic therapy [0.03%]
晚期非小细胞肺癌的治疗策略：立体定向体部放射治疗、纵隔淋巴结清扫术及新型全身治疗
Simon Fung Fee Fung,Graham W Warren,Anurag K Singh
Simon Fung Fee Fung
Non-small-cell lung cancer (NSCLC) remains a leading cause of cancer mortality. The majority of patients present with advanced (stage III-IV) disease. Such patients are treated with a variety of therapies including surgery, radiation, and c...
Samjot Singh Dhillon,Elisabeth U Dexter
Samjot Singh Dhillon
Bronchoscopic techniques have seen significant advances in the last decade. The development and refinement of different types of endobronchial ultrasound and navigation systems have led to improved diagnostic yield and lung cancer staging c...
Meat consumption, ornithine decarboxylase gene polymorphism, and outcomes after colorectal cancer diagnosis [0.03%]
饮食肉类摄入、鸟氨酸脱羧酶基因多态性与结直肠癌患者的预后关系研究
Jason A Zell,Bruce S Lin,Argyrios Ziogas et al.
Jason A Zell et al.
Background: Dietary arginine and meat consumption are implicated in colorectal cancer (CRC) progression via polyamine-dependent processes. Polymorphism in the polyamine-regulatory gene, ornithine decarboxylase 1 (Odc1, rs...
Alterations in keratins and associated proteins during 4- Nitroquinoline-1-oxide induced rat oral carcinogenesis [0.03%]
4-硝基喹啉-1-氧化物诱导的大鼠口腔粘膜癌变过程中角蛋白及相关蛋白质的变化
Deepak Kanojia,Sharada S Sawant,Anita M Borges et al.
Deepak Kanojia et al.
Background: Oral squamous cell carcinoma (OSCC) is the sixth largest group of malignancies globally and the single largest group of malignancies in the Indian subcontinent. Despite the advances in treatment and therapeuti...
CyclinD1 protein plays different roles in modulating chemoresponses in MCF7 and MDA-MB231 cells [0.03%]
CyclinD1蛋白在调节MCF7和MDA-MB231细胞的化学反应性中扮演不同的角色
Yuan Sun,Dianzhong Luo,D Joshua Liao
Yuan Sun
Background: CyclinD1 is an essential sensor and activator of cell cycle initiation and progression; overexpression of cyclinD1 is linked to various human cancers, including breast cancer. The elevated cyclinD1 in some typ...