Impact of single-nucleotide variants and nutritional status on population pharmacokinetics of Doxorubicin, and its effect on cardiotoxicity in children with leukemia [0.03%]
单核苷酸变异和营养状况对儿童急性淋巴细胞白血病表鬼素群体药代动力学的影响及与心脏毒性的关系
Jesús Alonso Gándara-Mireles,Ismael Lares-Asseff,Elio Aarón Reyes Espinoza et al.
Jesús Alonso Gándara-Mireles et al.
Purpose: Doxorubicin is an important antineoplastic agent with wide interindividual variability in response to treatment and in its cardiotoxic effects. To determine the effect of genotypic status of three single-nucleot...
Oral oncolytic monitoring pilot with patient-reported outcomes and adherence assessments [0.03%]
基于患者报告的结果和用药依从性评估的口服抗肿瘤药物监测试点项目
Jessie Signorelli,Christopher Bell,Stephanie Monaco
Jessie Signorelli
Introduction: Patients on oral oncolytics are responsible for self-monitoring adherence and adverse drug reactions (ADRs). Oncology pharmacists are in position to focus on quality and safety of care for patients on oncoly...
Combination of available topical beta-blockers and antibiotic ointment for epidermal growth factor receptor tyrosine kinase inhibitor-induced paronychia and pseudopyogenic granulomas in Taiwan [0.03%]
台湾地区表皮生长因子受体酪氨酸激酶抑制剂诱发的假脓性肉芽肿和甲沟炎的治疗组合疗法分析
Hui-Lin Liu,Cheng-Hao Chuang,Chin-Ling Chen et al.
Hui-Lin Liu et al.
Background: Painful paronychia and pseudopyogenic granuloma (PG) are common adverse drug reactions (ADRs) associated with the use of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) to treat non-sma...
Kelsey Finch,Deepankar Sharma,Stephanie Wagner
Kelsey Finch
Introduction: Iatrogenic lung injury is a very rare, albeit serious complication with antineoplastic therapy, including immunomodulatory drugs. Pneumonitis typically presents clinically with symptoms such as cough, dyspne...
Switching to daratumumab SC from IV is safe and preferred by patients with multiple myeloma [0.03%]
多发性骨髓瘤患者从静脉注射转换为皮下注射daratumumab安全且更受患者青睐
Maria-Victoria Mateos,Sophie Rigaudeau,Supratik Basu et al.
Maria-Victoria Mateos et al.
Introduction: Two phase 3 studies demonstrated superior efficacy of intravenous daratumumab (DARA IV) plus bortezomib/melphalan/prednisone (ALCYONE) or lenalidomide/dexamethasone (Rd; MAIA) versus standard-of-care regimen...
Risk factors associated with nausea and vomiting in children with cancer receiving chemotherapy [0.03%]
儿童肿瘤化疗致恶心呕吐的危险因素分析
Astrid Eliasen,J Kornholt,R Mathiasen et al.
Astrid Eliasen et al.
Introduction: Despite treatment with antiemetic medications, nausea remains uncontrolled for many children receiving chemotherapy. One reason is that risk factors for nausea in children remain poorly explored. The purpose...
Impact of oral chemotherapy pharmacists on cost avoidance of oral oncolytics in an integrated health system [0.03%]
综合健康系统中口腔化疗药房对口服抗肿瘤药物成本避免的影响
Analia L Nguyen
Analia L Nguyen
Background: While the impact of oncology pharmacist interventions on patient outcomes has been well-documented in previous studies, there is a scarcity of articles relating to oncology pharmacists' impact on cost avoidanc...
Ocular toxicity following carboplatin chemotherapy for neuroendocrine tumour of the bladder [0.03%]
用于治疗膀胱类癌的卡铂化疗后的眼部毒性
Jia Ng,Muhayman Sadiq,Qasim Mansoor
Jia Ng
Introduction: Carboplatin is a commonly used platinum analogue chemotherapeutic agent that is similar to cisplatin but is known to be better tolerated. This case report outlines a case of ocular toxicity following carbopl...
Pharmacy utilization of electronic patient-reported outcomes in oncology populations [0.03%]
肿瘤患者人群中电子病人报告结果的药房利用情况
Lauren M Aschermann,Michael Berger,Craig Vargo et al.
Lauren M Aschermann et al.
Telehealth applications are demonstrated to be useful tools for patients with cancer to facilitate improvements in quality of care. The use of electronic patient-reported outcomes is one way to leverage telehealth to better understand outco...
Elevated transaminases and development of cardiomyopathy in a 32-year-old woman with metastatic breast cancer after treatment with ribociclib followed by palbociclib [0.03%]
一名接受瑞博西利治疗后病情进展为帕博西利的32岁转移性乳腺癌女性患者出现转氨酶升高和心肌病
Christina Watts,Karin Nadori
Christina Watts
Introduction: Cyclin-dependent kinase 4 and 6 inhibitors, ribociclib and palbociclib, are associated with reports of transaminitis and adverse cardiac events. ...