Changing trends in androgen deprivation therapy prescribing for prostate cancer in England, 2015-2024 [0.03%]
英国2015-2024年前列腺癌雄激素剥夺治疗的处方趋势变化
Gayasha Somathilake,Christopher Wood,Colm Andrews et al.
Gayasha Somathilake et al.
IntroductionGonadotropin-releasing hormone (GnRH) agonists are the most commonly used form of androgen deprivation therapy (ADT) for advanced prostate cancer, often prescribed with radiotherapy or chemotherapy. This study examined national ...
Stability challenges of oncological medicines: The overlooked role of industrial pharmacy [0.03%]
肿瘤药物稳定性问题：被忽视的工业药学作用
Ali Cherif Chefchaouni,Ismail Bennani,Soumaya El Baraka et al.
Ali Cherif Chefchaouni et al.
BackgroundEnsuring the stability and quality of oncological medicines remains a major challenge across both industrial and hospital settings. These products are often biologics or highly sensitive compounds are vulnerable to chemical, physi...
Drug-related problems among pediatric patients with cancer admitted to the pediatric haemato-oncology department: A prospective observational study [0.03%]
儿科肿瘤病房收治的儿童癌症患者药物相关问题的前瞻性观察研究
Nabin Pathak,Bijaya Basyal,Shreya Dhungana et al.
Nabin Pathak et al.
BackgroundPediatric patients undergoing chemotherapy often need to take multiple medications. Consequently, they may experience drug-related problems (DRPs), including adverse drug reactions, drug interactions, and various medication errors...
Time-saving impact of two generation model chemotherapy compounding robots on pharmacists' daily workflow: A long-term evaluation [0.03%]
两种代次化疗配药机器人对药师日常工作流程节时效果的长期评估
Yuki Tonogai,Masahiro Kondo,Yasuhiro Horita et al.
Yuki Tonogai et al.
IntroductionEnhancing the efficiency of anticancer drug preparation enables pharmacists to dedicate more time to providing pharmaceutical care. Although chemotherapy compounding robots are globally widespread, their long-term quantitative i...
Variability of busulfan area under the concentration-time curve in children with different hematologic disorders [0.03%]
不同血液系统疾病儿童 BUS 的浓度-时间曲线下面积的差异性研究
Jie Deng,Hui Li,Zhen Peng et al.
Jie Deng et al.
PurposeLimited data on the effect of hematologic disorders on the busulfan (Bu) pharmacokinetics in children undergoing allogeneic hematopoietic stem cell transplantation (HSCT) is available to date. This study aimed to investigate pharmaco...
Content validation of a pre-treatment oral oncolytic non-adherence estimator (ORACLE) [0.03%]
预先治疗口服抗肿瘤药物不依从估算器（ORACLE）的内容验证
Benyam Muluneh,Marie E Sirek,Tahsin Imam et al.
Benyam Muluneh et al.
BackgroundOral anti-cancer treatment is commonly used, and non-adherence can negatively affect outcomes. The Oral Oncolytic Non-Adherence Estimator (ORACLE) was designed to prospectively categorize patients into risk levels by considering c...
Cardioprotection in oncology: Mechanisms, risks and therapeutic strategies [0.03%]
肿瘤心脏病学：机制、风险和治疗策略
E Plotnikov,V Chernov,R Zelchan et al.
E Plotnikov et al.
Objectives of this review is to conduct an analysis of current data of cardiotoxicity of anticancer drugs and radiation therapy, methods of cardiovascular risk stratification, strategies for primary and secondary cardioprotection, approache...
Safe handling of cytotoxic and other hazardous drugs: Knowledge and practices among oncology staff in a teaching hospital [0.03%]
教学医院肿瘤科工作人员处理细胞毒性药物和其他危险药物的相关知识和实践状况调查分析
Kofi Boamah Mensah,Adwoa Bemah Boamah Mensah,Ebenezer Wiafe et al.
Kofi Boamah Mensah et al.
BackgroundCytotoxic drugs play a crucial role in cancer care but are highly hazardous to the health of healthcare workers if not handled safely. However, despite global guidelines for safe handling, knowledge and practice gaps persist, part...
Impact of an oncology pharmacist-led, well-developed and validated chemotherapy order template on quality of life in breast cancer patients: A randomized controlled trial [0.03%]
肿瘤药剂师主导的、完善而有效的化学疗法订单模板对乳腺癌患者生存质量的影响：一项随机对照试验
Vivek Patil,Madiwalayya S Ganachari,Rohan Bhise et al.
Vivek Patil et al.
BackgroundBreast cancer treatment with chemotherapy often affects patients' quality of life despite therapeutic benefits. This study evaluated the impact of a standardized Chemotherapy Order Template on quality of life in breast cancer pati...
Effectiveness and safety of trastuzumab-anns compared to reference trastuzumab among patients with HER2-positive breast cancer: A non-inferiority study [0.03%]
曲妥珠单抗类似物与原研曲妥珠单抗治疗HER2阳性乳腺癌患者的疗效和安全性比较：非劣效性研究
Patrick Shin,Fang Niu,Dara D Nguyen et al.
Patrick Shin et al.
IntroductionThis study evaluated the real-world effectiveness and safety of biosimilar trastuzumab-anns to the reference trastuzumab in a United States (U.S.) population.MethodsThis observational, multicenter, non-inferiority cohort study u...