Preventive effects of vitamin D on epileptic seizures and its regulation of PTEN and autophagy in acute epilepsy mouse models [0.03%]
维生素D对急性癫痫小鼠模型的预防作用及其对PTEN和自噬的调节作用
Jiahao Liu,Jiawei Li,Yuanyuan Liu et al.
Jiahao Liu et al.
Objective: Epilepsy treatments often lead to vitamin D (VitD) deficiency. Although vitamin D₃ (VitD3) has been shown to reduce epileptic symptoms by 43%, its preventive effects remain unclear. This study investigated the...
Lactobacillus yogurts alleviate anxious- and depressive-like effects in CUMS mice via multiple pathways and regulating gut-brain axis [0.03%]
乳酸菌酸奶通过多条通路调节肠脑轴缓解慢性不可预测性温和应激小鼠的抑郁和焦虑样行为
Chunyang Zheng,Song Wei,Fulei Liu et al.
Chunyang Zheng et al.
Background: Current researches suggest that the microbiota-gut-brain axis plays a critical role in modulating human cognition and emotion, particularly in the context of psychiatric disorders. Probiotic fermented dairy products have been sh...
Redox and bioenergetic modulation by eupatilin attenuated neuropathic allodynia in mice with diet-induced diabetes [0.03%]
红系和生物能量调节剂埃帕蒂林可减轻饮食诱导糖尿病小鼠的神经病理性触诱发痛
You-Ya Fan,Xue-Mei Li,Feng Xu et al.
You-Ya Fan et al.
Objectives: Painful diabetic neuropathy poses a devastating health burden, with one-third of diabetic patients being afflicted. Currently, most of the neuropathic pain drugs have shown insufficient efficacy, significant adverse reactions an...
Association between vitamin D deficiency, low high density lipoprote in cholesterol and higher risk of activities of daily living disability and dementia in Chinese adults aged over 65 years [0.03%]
维生素D缺乏、低高密度脂蛋白胆固醇与我国老年人日常生活活动残疾和痴呆风险增加有关联：一项基于人口的前瞻性研究
Xiao Ren,Minglan Jiang,Yiqun Li et al.
Xiao Ren et al.
Background: Activities of daily living (ADL) disability and dementia are major contributors to the growing burden of ageing-related public health challenges in China. ...
Reversal of early-life high fat diet prevents spatial discrimination deficits corresponding with altered brain inflammatory and metabolic profiles in male C57BL/6J mice [0.03%]
早期高脂肪饮食通过改变脑部炎症和代谢谱型导致小鼠空间辨别能力下降及逆转作用：在C57BL/6J雄性小鼠中的研究
Caleb S Bailey,McKenna C Green,Meggie J Coleman et al.
Caleb S Bailey et al.
Objectives: High-fat diet is well-known to contribute to systemic and central nervous system dysfunction and represents a modifiable risk factor for cognitive decline. A recent surge of new weight loss medications has dem...
Probiotics restore GABAergic neurons and attenuate postnatal seizures in periventricular leukomalacia [0.03%]
probiotics通过恢复GABA能神经元来缓解Periventricular Leukomalacia导致的新生儿癫痫发作
Jia-Shing Chen,Ming-Jung Tu,Yu-Ming Chang et al.
Jia-Shing Chen et al.
Objectives: Postnatal epilepsy often arises after periventricular leukomalacia (PVL) in preterm infants and resists to treatment. Its underlying mechanisms and potential preventive strategies remain unclear. Probiotics, known to alleviate m...
Mind over meal: affective neuroscience perspectives on emotional patterns in eating disorders [0.03%]
情系饮食：情感神经科学视角下的进食障碍情感模式
Hagar Hurvitz,Omer Horovitz
Hagar Hurvitz
Background: Recent research highlights the central role of emotion in psychopathology, with Panksepp's Affective Neuroscience Theory identifying seven primary emotional systems critical for mammalian survival. Although th...
Effect of encapsulated spice oleoresins on chronic unpredictable mild stress-induced depression and gut microbiome modulation in mice model [0.03%]
包封香料浸膏对慢性不可预测轻度应激小鼠模型抑郁行为及肠道菌群的改善作用研究
Rajashri Kulal,Mohammed Touseef Khan,Babasaheb Bhaskarrao Borse et al.
Rajashri Kulal et al.
Depression affects millions globally, prompting the search for novel treatments. Natural compounds like spice oleoresins show promise due to their bioactive constituents. This study explores the use of Hydroxypropyl-beta-cyclodextrin (HPBCD...
Efficacy of branched chain amino acid administration on cognitive function: a systematic review [0.03%]
支链氨基酸对认知功能的影响：系统评价
Haya Majid,Sajad Ul Islam,Sunil Kohli et al.
Haya Majid et al.
Background: Branched chain amino acids (BCAA) are essential amino acids that include leucine, isoleucine, and valine. Recent studies indicate that BCAAs might influence cognitive health. This systematic review aims to exa...
Effect of physical training and palatable diet consumption on the expression of endocannabinoid system components in the rat brain [0.03%]
运动和美食摄入对大鼠脑内内源性大麻素系统组分表达的影响
Paulo M A Lima,Beatriz A Lima,Gleisy K N Gonçalves et al.
Paulo M A Lima et al.
Objective: The endocannabinoid system (ECS) plays a pivotal role in regulating energy balance. While ECS activation stimulates appetite and increases preference for palatable food, it also enhances energy expenditure by m...