Eicosapentaenoic acid alleviates fibromyalgia-like pain by modulating microglia, astrocytes, and toll-Like receptor 4 signaling in the mice cerebellum [0.03%]
二十碳五烯酸通过调节小鼠小脑中的微胶质细胞、星形胶质细胞和TLR4信号减轻类纤维肌痛疼痛
I-Han Hsiao,Hsin-Cheng Hsu,I-Ying Lin et al.
I-Han Hsiao et al.
Fibromyalgia (FM) is a widespread systemic pain disorder often accompanied by symptoms such as insomnia, mania, obesity, and depression. FM is difficult to diagnose and, therefore, cannot be effectively treated with current medical approach...
Effects of a single 10-hour daytime fasting intervention on mood and appetite in female adults with and without obesity: a real-world feasibility trial [0.03%]
针对肥胖和非肥胖成人女性的为期一天的日常白天禁食干预对情绪和饥饿感的影响：一项现实世界的可行性试验
Jenneffer Rayane Braga Tibaes,Gabriela Barbosa Fagundes,Lais Bhering Martins et al.
Jenneffer Rayane Braga Tibaes et al.
Objective: Comparison of the effect of acute daytime fasting on mood, satiety, and neurotrophic factors in females with (OB) and without obesity (N-OB).Methods: Non-randomized single-arm feasibility trial. Data were collected at an outpatie...
Antidepressant potential of Carica Papaya fruit extract and diet: behavioral and physiological effects in mice models [0.03%]
番木瓜果实萃取物及饮食的抗抑郁潜能：以小鼠模型的行为学和生理学效果研究
Tejinder Kaur,Varinder Singh,Richa Shri
Tejinder Kaur
Carica papaya is a popular fruit valued for its nutritive and diverse medicinal activities. Traditionally, it is used for its varied effects, including those on the central nervous system. The present study investigated the effect of hydroe...
Traumatic brain injury: a review of pathophysiology and therapeutic potential of polyphenols [0.03%]
脑创伤的病理和酚类药物治疗潜力的研究综述
Sanaz Keshavarz Shahbaz,Pourya Fathollazadeh,Isareza Zare et al.
Sanaz Keshavarz Shahbaz et al.
Objectives: Traumatic brain injury (TBI) is severe and may become debilitating for sufferers as a result of damage to the brain. Defining features include primary trauma, axonal damage, as well as both diffuse and focal l...
Brandon Lucke-Wold,Nathan D Zasler,Fnu Ruchika et al.
Brandon Lucke-Wold et al.
Background: Traumatic brain injury (TBI) continues to be a leading cause of morbidity and mortality. Nutraceuticals and supplements have emerged as potential therapeutics to enhance brain recovery post-injury. ...
Hypothalamic regulated physiological function and gene expression changes suggest high fructose corn syrup intake affects neurodevelopment in adolescent female rats [0.03%]
玉米糖浆的摄入通过影响青春期雌性大鼠下丘脑调控的生理功能和基因表达改变神经发育
Sundus S Lateef,Vanessa L Mueller,Eloisa Vendematti et al.
Sundus S Lateef et al.
Objective: To investigate the impact of drinking different caloric sweeteners from immaturity to young adulthood on hypothalamic controlled physiological functions and hypothalamic global gene expression using a rat model...
Individual and combined walnut oil and blueberry attenuate lipopolysaccharide-induced neuroinflammation in rat microglia [0.03%]
单独和联合使用的胡桃油和蓝莓减轻脂多糖诱导的Sprague-Dawley大鼠小胶质细胞神经炎症反应
Amanda N Carey,Derek R Fisher,Danielle S Cahoon et al.
Amanda N Carey et al.
Objectives: Chronic microglial activation drives neuroinflammation, contributing to neurodegenerative diseases and cognitive decline. Walnuts and blueberries (BB) have been demonstrated to reduce neuroinflammation, but it...
Effects of lauric acid on cognitive impairment in a scopolamine-induced Alzheimer's disease-like rat model [0.03%]
肉豆蔻酸对 scopolamine诱导的阿尔茨海默病样模型大鼠认知障碍的影响
Fajemidagba Grace Ayobami,Oluwadare Joshua Ogundipe,Ajibade Adewale Emmanuel et al.
Fajemidagba Grace Ayobami et al.
Background: Alzheimer's disease (AD) is a multi-factorial type of dementia that poses a social and medical burden in that no effective treatment has been achieved yet. Impaired brain glucose metabolism is one of the major pathophysiological...
Limited effects of omega-3 supplementation on offspring metabolic and hypothalamic programming under a maternal cafeteria diet [0.03%]
ω-3膳食补充对改善母鼠西式cafeteria饮食造成的影响有限
Aslihan Koc,Irem Dogan,Zeynep Caferoglu Akin et al.
Aslihan Koc et al.
Objectives: This study aimed to investigate the impact of supplementing the maternal cafeteria diet with omega-3 fatty acids (ω3) on serum glucose, insulin, and leptin levels, as well as hypothalamic mRNA expression leve...
Protective effect of safflower oil supplementation on sciatic nerve crush injury in rats [0.03%]
红花籽油对大鼠坐骨神经压伤的保护作用
Qin Li,Yuting Wang,Songyi Wei et al.
Qin Li et al.
Objective: This study aimed to assess the effect of safflower oil (SO), a high-quality edible oil derived from seeds of Carthamus tinctorius L. possessing multiple bioactivities, on rats that underwent sciatic nerve crush...