Looking ahead at the potential benefits of biotechnology-derived allergen therapeutics [0.03%]
展望生物技术来源过敏治疗药物的潜在益处
Jason Behrmann
Jason Behrmann
While biotechnology-derived allergen therapeutics show promise in improving the safety of immunotherapy, they may prove to have additional benefits in comparison to conventional allergenic extracts that deserve commentary. These issues rang...
Rob C Aalberse
Rob C Aalberse
The prediction of allergen cross-reactivity is currently largely based on linear sequence data, but will soon include 3D information on homology among surface exposed residues. To evaluate procedures for these predictions, we need ways to q...
Viswanath P Kurup,Christy S Barrios,Raghavan Raju et al.
Viswanath P Kurup et al.
Background: There has been a worldwide increase in allergy and asthma over the last few decades, particularly in industrially developed nations. This resulted in a renewed interest to understand the pathogenesis of allerg...
Ngoc P Ly,Begoña Ruiz-Pérez,Andrew B Onderdonk et al.
Ngoc P Ly et al.
Background: The mechanisms for the association between birth by cesarean section and atopy and asthma are largely unknown. Objective: T...
Molecular and immunological characterization of allergens from the entomopathogenic fungus Beauveria bassiana [0.03%]
贝奥武费里马氏霉菌过敏原的分子和免疫学表征
Greg S Westwood,Shih-Wen Huang,Nemat O Keyhani
Greg S Westwood
Background: Entomopathogenic fungi such as Beauveria bassiana are considered promising biological control agents for a variety of arthropod pests. Beauveria species, however, have the potential to elicit allergenic reacti...
Specific antibodies to recombinant allergens of Aspergillus fumigatus in cystic fibrosis patients with ABPA [0.03%]
肉芽肿性肺曲霉病患者的烟曲霉重组过敏原的特异性抗体反应
Viswanath P Kurup,Alan P Knutsen,Richard B Moss et al.
Viswanath P Kurup et al.
Background: Aspergillus fumigatus, a widely distributed fungus, has been implicated in causing life threatening infections as well as severe asthma and allergic diseases in man. Allergic affliction like allergic bronchopu...
Evaluation of the sensitization rates and identification of IgE-binding components in wild and genetically modified potatoes in patients with allergic disorders [0.03%]
过敏患者对野生和转基因土豆的致敏率评估及IgE结合组分鉴定
Soo-Keol Lee,Young-Min Ye,Sung-Ho Yoon et al.
Soo-Keol Lee et al.
Background: The potato is one of the most common types of genetically modified (GM) food. However, there are no published data evaluating the impact of genetic manipulations on the allergenicity of GM potatoes. To compare...
Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA) [0.03%]
两个欧洲队列中细胞因子基因多态性和特应性疾病（ECRHS-Basel和SAPALDIA）
M Imboden,A Nieters,A J Bircher et al.
M Imboden et al.
Background: Atopy and allergic phenotypes are biologically characterized by an imbalanced T helper cell response skewed towards a type 2 (TH2) immune response associated with elevated serum immunoglobulin E (IgE) levels. ...
Raja S Vadlamudi,David S Chi,Guha Krishnaswamy
Raja S Vadlamudi
In spite of recent advances with experiments on animal models, strongyloidiasis, an infection caused by the nematode parasite Strongyloides stercoralis, has still been an elusive disease. Though endemic in some developing countries, strongy...
A possible link between sinusitis and lower airway hypersensitivity: the role of Staphylococcal enterotoxin B [0.03%]
急性鼻窦炎与气道高反应性之间的关系及其可能的机制研究——金黄色葡萄球菌肠毒素B的作用
Tao Liu,Bin-Quan Wang,Ping-Chang Yang
Tao Liu
Background and aims: The prevalence of asthma has been keeping arising with unknown etiology. The cumulative evidence indicates that chronic rhinosinusitis (CRS) closely relates to asthma, but the detailed mechanisms rema...