Aspergillus fumigatus allergen expression is coordinately regulated in response to hydrogen peroxide and cyclic AMP [0.03%]
氢气化物和环核苷酸共同调控产烟曲霉过敏原的表达
Marcin G Fraczek,Rifat Rashid,Marian Denson et al.
Marcin G Fraczek et al.
Background: A. fumigatus has been associated with a wide spectrum of allergic disorders such as ABPA or SAFS. It is poorly understood what allergens in particular are being expressed during fungal invasion and which are r...
Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study [0.03%]
两项色氨酸代谢酶基因多态性与儿童过敏性哮喘关联的病例对照研究
Aleksandra Szczepankiewicz,Anna Bręborowicz,Paulina Sobkowiak et al.
Aleksandra Szczepankiewicz et al.
Background: Histamine-metabolizing enzymes (N-methyltransferase and amiloride binding protein 1) are responsible for histamine degradation, a biogenic amine involved in allergic inflammation. Genetic variants of HNMT and ...
Bimodal action of the flavonoid quercetin on basophil function: an investigation of the putative biochemical targets [0.03%]
檞皮素对嗜碱性细胞功能的双相作用：疑似生化靶点的研究
Salvatore Chirumbolo,Marta Marzotto,Anita Conforti et al.
Salvatore Chirumbolo et al.
Background: Flavonoids, a large group of polyphenolic metabolites derived from plants have received a great deal of attention over the last several decades for their properties in inflammation and allergy. Quercetin, the ...
The increase of plasma galectin-9 in a patient with insulin allergy: a case report [0.03%]
一例胰岛素过敏患者的血浆半乳糖凝集素9升高现象：病例报告
Haorile Chagan-Yasutan,Beata Shiratori,Umme Ruman Siddiqi et al.
Haorile Chagan-Yasutan et al.
Allergic reaction to insulin is known to be associated with eosinophilia and hyper IgE. Recent report showed that eosinophilia is related with the increased synthesis of galectin-9 (GAL-9) and osteopontin (OPN). Here, we examined plasma lev...
Cord blood versus age 5 mononuclear cell proliferation on IgE and asthma [0.03%]
脐带血与5岁时单个核细胞的增殖、IgE和哮喘的关系
Carolyn Chang,Kevin Gauvey-Kern,Alina Johnson et al.
Carolyn Chang et al.
Background: Fetal immune responses following exposure of mothers to allergens during pregnancy may influence the subsequent risk of childhood asthma. However, the association of allergen-induced cord blood mononuclear cel...
Alon H Nissim Ben Efraim,Ron Eliashar,Francesca Levi-Schaffer
Alon H Nissim Ben Efraim
Background: Eosinophils are involved in various inflammatory processes including allergic inflammation during which angiogenesis has been documented. Angiogenesis is most likely connected to the hypoxia which characterize...
IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring [0.03%]
过敏母亲传输的IgG减少母乳喂养后代的过敏敏感性
Adam P Matson,Roger S Thrall,Ektor Rafti et al.
Adam P Matson et al.
Background: The mechanism(s) responsible for the reduced risk of allergic disease in breastfed infants are not fully understood. Using an established murine model of asthma, we demonstrated previously that resistance to a...
Does improvement management of atopic dermatitis influence the appearance of respiratory allergic diseases? A follow-up study [0.03%]
特应性皮炎的管理改善是否会影响呼吸道过敏性疾病的发生？一项随访研究
Giampaolo Ricci,Annalisa Patrizi,Arianna Giannetti et al.
Giampaolo Ricci et al.
Background: Atopic dermatitis (AD) is often the prelude to allergic diseases. The aim of this study was 1) to evaluate if an integrated management regime could bring about a change in the evolution of the disease in compa...
Recombinant phospholipase A1 (Ves v 1) from yellow jacket venom for improved diagnosis of hymenoptera venom hypersensitivity [0.03%]
用于改善膜翅目昆虫毒液过敏诊断的重组磷脂酶A1(Vesv1)
Henning Seismann,Simon Blank,Liliana Cifuentes et al.
Henning Seismann et al.
Background: Hymenoptera venoms are known to cause life-threatening IgE-mediated anaphylactic reactions in allergic individuals. Proper diagnosis of hymenoptera venom allergy using venom extracts is severely affected by mo...
Molecular defects in the mannose binding lectin pathway in dermatological disease: Case report and literature review [0.03%]
皮肤病中甘露糖结合凝集素途径分子缺陷：病例报告及文献综述
Christopher Miller,Sara Wilgenbusch,Mini Michaels et al.
Christopher Miller et al.
Mannose-binding lectin (MBL) and the Mannose-binding lectin-associated serine proteases (MASPs) are an essential aspect of innate immune responses that probably play an important but understudied role in cutaneous function. The MBL-MASP pat...