Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms [0.03%]
老年人过敏性疾病：生物学特征及主要免疫和非免疫机制
Maria Teresa Ventura,Nicola Scichilone,Roberto Paganelli et al.
Maria Teresa Ventura et al.
Life expectancy and the number of elderly people are progressively increasing around the world. Together with other pathologies, allergic diseases also show an increasing incidence in geriatric age. This is partly due to the growing emphasi...
Clinical management, expectations, and satisfaction of patients with moderate to severe allergic rhinoconjunctivitis treated with SQ-standardized grass-allergen tablet under routine clinical practice conditions in Spain [0.03%]
西班牙日常临床实践条件下口服过敏原片治疗中至重度过敏性结膜炎患者的临床管理、期望和满意度研究
Tomás Chivato,Pedro Álvarez-Calderón,Carmen Panizo et al.
Tomás Chivato et al.
Background: Sublingual immunotherapy has been proven as a well-tolerated and effective treatment for allergic rhinitis. Within this type of treatment, GRAZAX® is the most documented product in terms of safety and efficac...
Paola Lucia Minciullo,Antonio Cascio,Stefania Isola et al.
Paola Lucia Minciullo et al.
The tapeworm Taenia (T.) solium can be responsible for two different conditions: taeniasis and cysticercosis. Helminth infections in human host cause an immune response associated with elevated levels of IgE, tissue eosinophilia and mastocy...
Erminia Ridolo,Valerie Melli,Gianluigi De&#x; Angelis et al.
Erminia Ridolo et al.
Eosinophilic diseases of the gastrointestinal tract, including eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), are rare chronic pathologies of the digestive system, with an immuno-mediated pathogenesis. Recent data su...
Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients [0.03%]
人类Th17细胞产生丝氨酸蛋白酶3样蛋白1且其水平与幼年特发性关节炎患者的炎症程度相关
Manuela Capone,Laura Maggi,Veronica Santarlasci et al.
Manuela Capone et al.
Background: CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that ch...
HIV-1 Nef promotes migration and chemokine synthesis of human basophils and mast cells through the interaction with CXCR4 [0.03%]
HIV-1Nef通过与CXCR4相互作用促进人类basophil和肥大细胞迁移及细胞因子合成
Francesca Wanda Rossi,Nella Prevete,Felice Rivellese et al.
Francesca Wanda Rossi et al.
Background: The Nef protein can be detected in plasma of HIV-1-infected patients and plays a role in the pathogenesis of HIV-1. Nef produced during the early stages of infection is fundamental in creating the ideal enviro...
Dose-dependence of protection from systemic reactions to venom immunotherapy by omalizumab [0.03%]
奥马珠单抗剂量依赖性地预防毒液免疫治疗的全身反应
Elisa Boni,Cristoforo Incorvaia,Marina Mauro
Elisa Boni
Background: Systemic reactions (SR) to venom immunotherapy (VIT) are rare but may occur, with a rate significantly higher for honeybee than for vespid VIT. In patients with repeated SRs to VIT it is difficult to reach the...
Gianluca Bagnato,William Neal Roberts,Davide Sciortino et al.
Gianluca Bagnato et al.
Background: Systemic sclerosis (SSc) is a complex autoimmune disease characterized by vascular alterations and autoimmune activation leading to widespread organ fibrosis. At the early stage of disease when organ involveme...
A Linneberg,K Dam Petersen,J Hahn-Pedersen et al.
A Linneberg et al.
This meta-analysis compared the health-related quality of life (HRQL) of patients with allergic rhinitis (AR) and/or allergic asthma (AA) caused by perennial house dust mite (HDM) versus AR and/or AA caused by seasonal pollen allergy. Follo...
Marie-Pierre Piccinni,Letizia Lombardelli,Federica Logiodice et al.
Marie-Pierre Piccinni et al.
Autoimmune disorders are characterized by tissue damage, caused by self-reactivity of different effectors mechanisms of the immune system, namely antibodies and T cells. Their occurrence may be associated with genetic and/or environmental p...