Prophylactic Antimicrobials for Prevention of Febrile Neutropenia in Tumour-Bearing Dogs Treated With Lomustine [0.03%]
预防瘤胃中性粒细胞减少症犬发热的抗菌药物的预防作用（接受洛莫司汀治疗的犬）
Meredith Gumash,Olya A Martin,Stephanie E S Lindley et al.
Meredith Gumash et al.
CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosurea), lomustine, is an oral alkylating agent in the nitrosourea subgroup. The dose-limiting toxicity of CCNU is neutropenia most frequently documented 7 days after its administration. Use of pro...
Lymphoid Aggregates in Canine Cutaneous and Subcutaneous Sarcomas: Immunohistochemical and Gene Expression Evidence for Tertiary Lymphoid Structures [0.03%]
犬皮肤和皮下肉瘤中淋巴细胞集合体的免疫组化及基因表达证据表明存在三级淋巴组织结构
Kristin Marie Rugh,Laura Vary Ashton,Paula Andrea Schaffer et al.
Kristin Marie Rugh et al.
Canine cutaneous/subcutaneous soft-tissue sarcomas (STS) are diversely derived mesenchymal neoplasms with a risk of recurrence and/or metastasis depending on the extent of surgical excision and histologic grade. Lymphoid aggregates (LAs) ar...
Flow Cytometry for the Detection and Quantification of Mast Cells in Lymph Nodes: A Prospective Study in 64 Dogs With Mast Cell Tumour [0.03%]
流式细胞术在淋巴结中肥大细胞的检测与定量：64只肿瘤病犬的前瞻性研究
Giulia Iamone,Carmit Chalfon,Laura Marconato et al.
Giulia Iamone et al.
Nodal metastasis is a negative prognostic factor in dogs with mast cell tumours (MCTs), thus early detection enables more informed decision-making and provides valuable prognostic information. The aim of this study is to assess the concorda...
Stromal Expression Profiling Reveals Immune-Driven Adaption to Malignancy in Canine Melanoma Subtypes [0.03%]
间质转录组分析揭示了免疫反应在犬恶性黑色素瘤亚型中的适应性响应
Erin Beebe,Christiane Krudewig,Zahra Motamed et al.
Erin Beebe et al.
Canine mucosal melanoma (CMM) is the most common oral malignancy in dogs and is significantly more aggressive than its cutaneous counterpart (CCM), yet the reasons for this disparity remain unclear. Cancer-associated stroma (CAS) plays a cr...
Relative Tumour Volume in Canine Oral Melanoma Staging and Prognosis [0.03%]
相对肿瘤体积在犬口腔黑色素瘤分期和预后中的作用
Marta L Silva,Inês Martinho,Margarida Rocha et al.
Marta L Silva et al.
Melanoma is one of the most common canine oral malignant tumours and is highly aggressive and metastatic, even at the early stages of development. Surgery relies on wide excision of the primary tumour and regional lymphadenectomy, with or w...
Clinical Utility of Circulating Cell-Free DNA as a Liquid Biopsy in Cats With Various Tumours [0.03%]
循环细胞游离DNA在不同肿瘤类型猫的临床应用价值
Michihito Tagawa,Hotaka Hiroi,Yuzuki Nakano et al.
Michihito Tagawa et al.
Only a limited number of tumour biomarkers are currently available in veterinary medicine, particularly in cats. Cell-free DNA (cfDNA) is an extracellular DNA fragment released upon cell death and is considered a minimally invasive biomarke...
Comparative Transcriptomes of Canine and Human Prostate Cancers Identify Mediators of Castration Resistance [0.03%]
比较犬和人类前列腺癌转录组鉴定去势抵抗介质
Marcela Riveros Angel,Bernard Séguin,Christiane V Löhr et al.
Marcela Riveros Angel et al.
Prostate cancer continues to be one of the most lethal cancers in men. While androgen deprivation therapy is initially effective in treating prostate cancer, most cases of advanced prostate cancer eventually progress to castration-resistant...
Comparative Study
Veterinary and comparative oncology. 2024 Dec;22(4):629-640. DOI:10.1111/vco.13017 2024
Stereotactic Radiation Therapy Planning, Dose Prescription and Delivery in Veterinary Medicine: A Systematic Review on Completeness of Reporting and Proposed Reporting Items [0.03%]
放射外科在兽医肿瘤学中的计划、剂量处方和递送的系统性回顾及其汇报项目的提议
Carla Rohrer Bley,Valeria Meier,Michelle Turek et al.
Carla Rohrer Bley et al.
Increasing numbers of dogs and cats with cancer are treated with stereotactic radiosurgery, stereotactic radiation therapy or stereotactic body radiotherapy (SRS, SRT or SBRT). We provide a systematic review of the current data landscape wi...
Effects of Lipophilic Statins on Cell Viability and Tissue Factor Expression in Canine Haemangiosarcoma Cells [0.03%]
他莫昔芬联合阿托伐他汀对犬心脏房颤模型影响的研究
Kosuke Kobayashi,Kohei Murakami,Kenji Baba
Kosuke Kobayashi
Canine haemangiosarcoma (HSA) is a highly aggressive cancer often associated with coagulation abnormalities. Statins, inhibitors of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR) clinically prescribed for hypercholesterolemia, are also b...
Use of Cystourethroscopy to Define the Gross Tumour Volume in Radiation Treatment Planning for Canine Genitourinary Carcinomas [0.03%]
膀胱镜定义放射治疗计划中泌尿生殖道肿瘤的临床靶体积上限
Clarissa C Freemyer,Tracy L Gieger,Shelly L Vaden et al.
Clarissa C Freemyer et al.
Radiotherapy (RT) is increasingly utilised for definitive-intent treatment of canine genitourinary carcinomas (CGUC). At our institution, the standard approach is to irradiate tomographically abnormal tissues gross tumour volume (GTV) plus ...