Newcastle Disease Virus Induces Pyroptosis in Canine Mammary Tumour CMT-U27 Cells via the TNFα/NF-κB/NLRP3 Signalling Pathway [0.03%]
新城疫病毒通过TNFα/NF-κB/NLRP3信号通路诱导犬乳腺肿瘤CMT-U27细胞发生焦亡
Mengqing Li,Yunjie Zhu,Meng Li
Mengqing Li
Mammary tumours are the most common type of neoplasm in female dogs, with nearly half being malignant. Oncolytic Newcastle disease virus (NDV) therapy has emerged as a novel cancer treatment option; however, its precise oncolytic mechanism ...
Tolerability Assessment of Orally Administered Paclitaxel With Encequidar in Dogs With Spontaneous Malignancy [0.03%]
口服紫杉醇与恩西喹达在患有自发恶性肿瘤的犬中的耐受性评估
Jordan Ziegler,Jacob Cawley,Stephanie Istvan et al.
Jordan Ziegler et al.
Paclitaxel is an antimitotic agent that targets elements of the cancer phenotype, including cell proliferation, DNA repair, and apoptosis, predicting its broad activity in a spectrum of cancers. An oral paclitaxel formulation has been devel...
Effect of Changes in Canine Thyroid Cancer Terminology on Caregiver Anxiety Levels and Treatment Preferences in a Scenario-Based Study [0.03%]
犬甲状腺癌术语变化对基于场景研究中护理人员焦虑水平和治疗偏好的影响
Bryanna M Glasspool,Laura Blackwood,Kelly L Bowlt Blacklock
Bryanna M Glasspool
In human medicine, the choice of medical terminology influences patients' choice of management options and associated anxiety levels in relation to their diagnoses. The objective of this study was to determine the association between canine...
The Outcomes and Surgical Complications of Cats With Oral Squamous Cell Carcinoma Treated With Total Glosso-Mandibulectomy: 20 Cases (2008-2022) [0.03%]
20例舌颌骨切除术治疗猫口腔鳞状细胞癌的效果及手术并发症（2008-2022）
Taisuke Iwata,Masanao Ichimata,Atsushi Fujita et al.
Taisuke Iwata et al.
Feline oral squamous cell carcinoma (FOSCC) is the most common oral malignancy in cats. In general, FOSCC develops rapidly and is highly locally invasive. The existing treatments for treating FOSCC are limited. The objective of this single-...
Early-Delayed Radiotoxicity Associated With Stereotactic Radiation Therapy Following a Daily 6 Gy × 5 (30 Gy) Protocol for Presumed Canine Intracranial Meningiomas [0.03%]
立体定向放射治疗后每天6gy×5（30gy）方案治疗疑似犬颅内脑膜瘤相关的早期延迟放射毒性
James Elliott
James Elliott
Early-delayed side effects (EDSEs) following treatment of canine intracranial meningiomas with 1-3-fraction stereotactic radiation therapy (SRT) can cause worsening neurologic signs, and one potential method of mitigating this toxicity is r...
Clinical Guidelines for Canine Transmissible Venereal Tumour Treatment: Systematic Review and Meta-Analysis [0.03%]
犬传染性性病肿瘤治疗的临床指南：系统评价和荟萃分析
Pedro Antônio Bronhara Pimentel,Antonio Giuliano,Petros Odatzoglou et al.
Pedro Antônio Bronhara Pimentel et al.
The treatment of canine transmissible venereal tumour (CTVT) has evolved since its initial description in 1810. Initially considered untreatable in the early 20th century, extensive research over time has significantly advanced our understa...
Adjuvant Chemotherapy Is Associated With Prolonged Survival Time in Small-Breed Dogs Undergoing Amputation for Appendicular Osteosarcoma [0.03%]
接受截肢治疗的四肢骨肉瘤小型犬的辅助化疗可延长其生存时间
Stefano Zanardi,Silvia Sabattini,Federica Rossi et al.
Stefano Zanardi et al.
Adjuvant chemotherapy is a well-established treatment for large-breed dogs with appendicular osteosarcoma; however, it is unclear if it improves outcomes in small-breed dogs due to limited focused studies. This retrospective study aimed to ...
PD-L1, PD-1, and CTLA-4 mRNA In Situ Expression by Canine Oral Melanoma Cells and Immune Cells of the Tumour Microenvironment [0.03%]
犬口腔黑色素瘤细胞和肿瘤微环境免疫细胞的PD-L1、PD-1和CTLA-4 mRNA原位表达
Greta Foiani,Erica Melchiotti,Katia Capello et al.
Greta Foiani et al.
Canine oral melanoma (OM) exhibits poor prognosis and limited treatment options. The success of immune checkpoint inhibitors (ICIs) in human melanoma has driven interest in similar therapeutic approaches in the dog, although the immunosuppr...
Body Composition Measurements as Predictive Variables for Outcomes of Canine Appendicular Osteosarcoma Treated With Stereotactic Body Radiation Therapy [0.03%]
立体定向放疗治疗犬四肢骨肉瘤预后的影响因素-身体组成测量指标的研究
Johnny Altwal,Lynn Griffin,Tiffany Wormhoudt Martin
Johnny Altwal
Body composition measurements (BCM), obtained via computed tomography (CT), have been used as predictors of survival, tumour recurrence, and post-surgical infections in human oncology. There are no reports on using BCM to predict outcomes o...
Precision in Parsing: Evaluation of an Open-Source Named Entity Recognizer (NER) in Veterinary Oncology [0.03%]
精准的解析能力：开放式命名实体识别器（NER）在兽医肿瘤学中的评估
Christopher J Pinard,Andrew C Poon,Andrew Lagree et al.
Christopher J Pinard et al.
Integrating Artificial Intelligence (AI) through Natural Language Processing (NLP) can improve veterinary medical oncology clinical record analytics. Named Entity Recognition (NER), a critical component of NLP, can facilitate efficient data...