Knockdown of Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase 2 Promotes an Epithelial-Like Phenotype in Canine Mammary Carcinoma Cells [0.03%]
犬乳癌细胞中敲除亚甲基四氢叶酸脱氢酶/环水解酶2可促进上皮样表型的形成
Yukino Machida,Remika Onagi,Kazuhiko Ochiai et al.
Yukino Machida et al.
In cancer cells, folate is metabolised in the cytoplasm and mitochondria. Folate metabolism mediates nucleic acid synthesis and, thereby, the growth of cancer cells. One of the enzymes within this folate metabolic pathway, methylenetetrahyd...
SHINE - Validation of Near Infrared Fluorescence Lymphography Against Lymphoscintigraphy for Sentinel Lymph Node Biopsy in Dogs With Mast Cell Tumours [0.03%]
荧光淋巴造影引导下犬类肥大细胞肿瘤 sentinel 淋巴结活检的验证研究
L E Chiti,P Beer,S M Ohlerth et al.
L E Chiti et al.
Lymphoscintigraphy is the gold standard among sentinel lymph node (SLN) mapping techniques. Unfortunately, lymphoscintigraphy is not readily accessible, leading to the need for validation of alternative techniques. The aim of this study is ...
Classification and Prognostication of B-Cell and T-Cell Multicentric Lymphoma in Dogs Using Serum MicroRNAs [0.03%]
基于血清microRNA对犬B细胞和T细胞多中心淋巴瘤的分类与预后判断
Latasha Ludwig,Heather Treleaven,Roger Moorehead et al.
Latasha Ludwig et al.
Canine multicentric lymphoma is a common malignancy in dogs. It often responds well to initial chemotherapy but frequently relapses and has a poor response to subsequent treatment. B-cell (BCL) and T-cell (TCL) lymphomas differ in both thei...
The Poly (ADP-Ribose) Polymerase-1 Enzyme Is Overexpressed in Various Solid Canine Tumours: An Immunohistochemical Study [0.03%]
犬多种实体瘤中多(腺苷二磷酸-核糖)聚合酶-1高表达：一项免疫组化研究
Shana De Vos,Simone Janssen,Sophie Favril et al.
Shana De Vos et al.
The enzyme poly (ADP-ribose) polymerase-1 (PARP-1) is crucial for cellular regulation and DNA repair. Its immunohistochemical overexpression is known in various human neoplasms, but it was not yet a topic of veterinary research. Formalin-fi...
Chemoresistance Cytological Score for Canine Transmissible Venereal Tumour: A Proposed System of Predicting Vincristine Resistance [0.03%]
犬传染性 venereal 肿瘤的化学耐药细胞学评分：一个预测 vincristine 耐药性的系统提案
Pedro Antônio Bronhara Pimentel,Mariana Pádua Costa,Isadora Maria Sátiro de Oliveira et al.
Pedro Antônio Bronhara Pimentel et al.
Canine transmissible venereal tumour (CTVT) is a common diagnosis in many low-income countries, and managing its chemoresistant cases can be challenging within the conventional vincristine sulfate chemotherapy protocol. Also, predictive mar...
Genotoxic Herbicide Exposures in Golden Retrievers With and Without Multicentric Lymphoma [0.03%]
金毛寻回犬的遗传毒性除草剂暴露情况分析：多中心淋巴瘤狗与健康狗之间的比较
Ashleigh N Tindle,Lauren M Krueger,Brenna Swafford et al.
Ashleigh N Tindle et al.
Canine multicentric lymphoma (CML) is one of the most common malignancies in dogs. Although breed risk is important, environmental factors such as herbicides have also been implicated. The objective of this study was to determine whether ge...
Retrospective Study Evaluating the Outcome and Efficacy of Stereotactic Body Radiation Therapy for the Treatment of Metastatic Abdominal Lymph Nodes in Dogs With Apocrine Gland Anal Sac Adenocarcinoma [0.03%]
回顾性研究评估犬阿波克瑞腺肛 sac 腺癌转移腹腔淋巴结立体定向体放射治疗的疗效分析
Tiffany W Martin,Theodore Chang,Mary-Keara Boss et al.
Tiffany W Martin et al.
Local treatment for dogs with regional lymph node metastasis secondary to apocrine gland anal sac adenocarcinoma (AGASACA) includes nodal extirpation or radiotherapy. Stereotactic body radiation therapy (SBRT) may provide a definitive inten...
Characterisation of Gene Expression in Canine Invasive Urothelial Carcinoma Using a NanoString-Based Urine Assay [0.03%]
使用基于NanoString的尿液检测对犬浸润性尿路上皮癌的基因表达进行特征分析
Ellen Marie Kuerbitz,Deepika Dhawan,Sagar Utturkar et al.
Ellen Marie Kuerbitz et al.
For human and canine invasive urothelial carcinoma (InvUC), there is growing interest in using the molecular characteristics of a tumour to guide individualised treatment strategies. The objective of this study was to use a non-invasive, ur...
Half-Body Radiation Therapy Results in a Prolonged Progression-Free Interval in Canine High-Grade Lymphoma After First Remission [0.03%]
犬高分级淋巴瘤在第一次缓解后半身放射治疗带来延长的无进展区间
Yen-Hao Erik Lai,Sarah Lyles,Mark Mitchell et al.
Yen-Hao Erik Lai et al.
An optimal protocol of adding wide-field irradiation to multi-agent chemotherapy for dogs with lymphoma has not been established. The aim of this retrospective case-control study was to evaluate the efficacy of a protocol combining chemothe...
Contrast-Enhanced Computed Tomography for Identification of Potential Malignancy in Canine Colorectal Mesenchymal Tumours [0.03%]
对比增强CT在犬 colorectal 间叶肿瘤潜在恶性识别中的应用研究
Alexandria D Bourgeois,Owen T Skinner,James J Karnia et al.
Alexandria D Bourgeois et al.
Cross-sectional imaging may be used to characterise the location and extent of colorectal mesenchymal tumours (CRMTs). Given the anticipated variation in tumour behaviour and varying morbidity based on surgical margins, a reliable, non-inva...