Treatment of Feline Lymphocytic Lymphoma/Chronic Inflammatory Enteropathy Complex With Low Dose Abdominal Cavity Radiation Therapy [0.03%]
低剂量腹腔放射治疗猫淋巴细胞淋巴瘤/慢性炎症性肠病复合征
Tracy L Gieger,Michael W Nolan,Jody Gookin et al.
Tracy L Gieger et al.
The goal of this prospective, single-arm pilot study was to assess tolerability and clinical benefit for cats with histologically confirmed lymphocytic lymphoma/chronic inflammatory enteropathy complex (FLL/CIE) treated with low-dose abdomi...
Genomic Evaluation of Canine Prostatic Carcinomas as a Model for the Human Disease [0.03%]
作为人类疾病的模型对犬前列腺癌进行基因组评估
Rachael Thomas,Jennifer A Luff,Allison N Dickey et al.
Rachael Thomas et al.
Spontaneous canine prostate cancer (PC) is widely considered a pertinent clinical model for the human disease. While over 95% of PC in men are adenocarcinomas, arising from prostatic glandular epithelium, it is increasingly recognised that ...
Evaluating the Impact of Elective Nodal Irradiation for Dogs With Oral Malignant Melanoma Undergoing Hypofractionated Radiotherapy [0.03%]
评估低分割放射治疗联合选择性淋巴结照射治疗犬口腔恶性黑色素瘤的疗效
Patricia Gualtieri,Lisa Group,David M Ruslander et al.
Patricia Gualtieri et al.
Hypofractionated radiotherapy (hRT) is often used to treat dogs with oral malignant melanoma (OMM); however, there is no consensus as to whether clinically uninvolved regional lymph nodes should be prophylactically irradiated. The objective...
Dose and Duration of Upfront Steroid Administration Have no Prognostic Impact in Dogs With Multicentric Diffuse Large B-Cell Lymphoma [0.03%]
诱导治疗中糖皮质激素的剂量和时长对多中心弥漫大B细胞淋巴瘤犬的预后无影响
Ilaria Maga,Silvia Sabattini,Valeria Martini et al.
Ilaria Maga et al.
Steroids provide rapid clinical improvement in dogs with multicentric diffuse large B-cell lymphoma (DLBCL). However, their use before chemotherapy can induce chemoresistance and compromise diagnostic yield due to increased apoptotic cells....
Investigation of a 4.3 Gy × 10-Fraction Volumetric Modulated Arc Therapy Protocol for Canine Prostatic Carcinoma: A Normal Tissue Complication Probability Study [0.03%]
一种犬前列腺癌容积调强弧形治疗4.3Gy×10-分割方案的正常组织并发症概率研究
MyoungHun Kim,InSeong Jeong,KiDong Eom et al.
MyoungHun Kim et al.
The fraction size in canine pelvic tumours has traditionally been limited to minimisze radiation toxicity. However, advancements in precision radiotherapy techniques have enabled the use of larger fraction sizes, thereby facilitating a redu...
Transferrin Receptor-1: Expression in Canine Mammary Tumours and In Vitro Therapeutic Applications [0.03%]
转铁蛋白受体1在犬乳腺肿瘤中的表达及体外治疗应用研究
Valentina Moccia,Nicolò Rensi,Giovanni Paolo Marullo et al.
Valentina Moccia et al.
The transferrin receptor-1 (TFR-1) is overexpressed in many types of human cancers and, in recent years, several studies have investigated its use as a preferential channel for drug cellular uptake in cancer therapy. In veterinary medicine,...
Polarisation Sensitive Optical Coherence Tomography Image Characteristics for Gastrointestinal Tumours and Normal Tissues at Surgical Margins in Dogs [0.03%]
用于犬胃肠道肿瘤及手术切缘正常组织的偏振敏感光学相干层析成像特征研究
Hannah L Weaver,Gabrielle S Fontes,Yi-Fan Shen et al.
Hannah L Weaver et al.
The treatment of choice for canine alimentary tract neoplasms is surgical excision, but it can sometimes be difficult to achieve wide margins due to neoplasm location, size, or distribution. Optical coherence tomography (OCT) is a rapid, no...
Molecular Classification Based on the Gene Expression Profiles in Canine Histiocytic Sarcoma Cells [0.03%]
基于基因表达谱的犬单核细胞来源的滑膜肉瘤分子分型研究
Hiroki Sakuma,Hirotaka Tomiyasu,Akiyoshi Tani et al.
Hiroki Sakuma et al.
The molecular abnormalities of canine histiocytic sarcoma (CHS) remain to be elucidated. We previously revealed that the sensitivities to dasatinib and trametinib were significantly various among CHS cell lines, indicating the differences i...
Evaluation of Decreased Kidney Function in Dogs Receiving Carboplatin: A Retrospective Cohort Study of 98 Dogs (2006-2024) [0.03%]
回顾性队列研究:评估卡铂给药犬的肾功能下降(2006-2024年,98例)
Andrew D Yale,Alvina So,Alexandra Guillén et al.
Andrew D Yale et al.
Decreased kidney function is observed in some people receiving carboplatin, but limited literature explores this in dogs. The aim of this study was to evaluate the incidence and risk factors for decreased kidney function in dogs receiving c...
Prognostic Role of Patient, Tumour and Radiomic Factors Influencing Outcomes in Dogs With Thyroid Cancer Treated With Iodine-131 [0.03%]
碘-131治疗甲状腺癌犬的患者、肿瘤和影像组学特征对预后的影响
Ibrahim Chamseddine,Caitlin Cowan,Lindsay Donnelly et al.
Ibrahim Chamseddine et al.
Radioactive iodine therapy (I-131) is widely used in both human and veterinary medicine for treating thyroid cancer, utilising the common biological behaviour of thyroid tissues. Recognising the need to better understand the prognostic fact...