Evaluation of the Amount of Compounded Chemotherapy Drugs: A Comparison Between Nine Compounding Pharmacies [0.03%]
九家调配药房化疗药物调配量的评估及比较研究
Samantha R Bajorek,Trina N Hazzah,John D Chretin et al.
Samantha R Bajorek et al.
The use of compounded formulations of chemotherapy in veterinary medicine is common. The purpose of this study was to evaluate the drug amount of two compounded chemotherapeutics (chlorambucil and cyclophosphamide) from multiple veterinary ...
Comparative Study
Veterinary and comparative oncology. 2024 Dec;22(4):536-541. DOI:10.1111/vco.13003 2024
Overactivation of Signal Transducer and Activator of Transcription 3 in Canine Hepatocellular Carcinoma and Its Prognostic Significance [0.03%]
信号转导及转录激活因子3在犬肝细胞癌中的过度活化及其预后意义
Hun Kyeong Shin,Hea Ji Chung,Wan Hee Kim
Hun Kyeong Shin
Phosphorylated signal transducer and activator of transcription 3 (pSTAT3), which is related to anti-apoptosis, cellular proliferation, invasion and migration of tumours, has prognostic significance in malignant tumours in humans as well as...
Incorporation of Biologic Variables Into the Staging for Canine Cutaneous and Subcutaneous Mast Cell Tumours: Proposal of the UBo pTNM System [0.03%]
犬皮肤和皮下类癌肿瘤分期中生物标志物的应用及Ubo pTNM系统的提出
Laura Marconato,Eugenio Faroni,Emiliano Battisti et al.
Laura Marconato et al.
Canine cutaneous mast cell tumours (MCTs) are currently staged based on the World Health Organization (WHO) classification, which has remained unchanged since its initial formulation. Our study aimed to assess the reliability of a novel pTN...
Blood Neutrophil-to-Lymphocyte Ratio as a Potential Prognostic Marker in Dogs ≤10 kg With Multicentric Lymphoma [0.03%]
体重≤10kg伴有多中心淋巴瘤犬血常规中性粒细胞-淋巴细胞比率作为潜在的预后标志物
SoYoung Park,Sehoon Kim,Yeon-Jung Hong et al.
SoYoung Park et al.
Canine lymphoma, the most prevalent haematopoietic tumour in dogs, presents significant challenges in veterinary oncology. This study investigates the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in small-sized dogs (≤10 kg...
Hotspot Exon 15 Mutations in BRAF Are Uncommon in Feline Tumours [0.03%]
家猫肿瘤中极少出现少见的BRAF热区突变Exon15变异
Kei Kuroki,Christine Tran Hoang,Anita M Rogic et al.
Kei Kuroki et al.
BRAF is one of multiple RAF proteins responsible for the activation of the MAPK cell signalling cascade involved in cell growth, differentiation, and survival. A hotspot BRAFV600E mutation, in exon 15, was determined to be a driver in 100% ...
Molecular and Pathobiology of Canine Mammary Tumour: Defining a Translational Model for Human Breast Cancer [0.03%]
犬乳头瘤病的分子和病理生物学：定义人类乳腺癌的转化模型
Adália F Oliveira-Lopes,Marcelo M Götze,Belarmino E Lopes-Neto et al.
Adália F Oliveira-Lopes et al.
Canine mammary tumours (CMT) have histological, clinicopathological and molecular resemblances to human breast cancer (HBC), positioning them as viable models for studying the human disease. CMT initiation and progression occur spontaneousl...
Comparison of Three Chemotherapy Protocols With Electrochemotherapy for the Treatment of Feline Cutaneous Squamous Cell Carcinoma [0.03%]
三种化疗方案与电化疗治疗猫皮肤鳞状细胞癌的比较研究
Nicolas Diop,David Sayag,Grégoire Bernardo Marques et al.
Nicolas Diop et al.
Electrochemotherapy (ECT) with intravenous (IV) and/or intratumoral (IT) bleomycin has shown considerable efficacy in the treatment of non-resectable feline cutaneous squamous cell carcinoma (cSCC), boasting response rates of up to 95%, but...
Comparative Study
Veterinary and comparative oncology. 2024 Sep;22(3):437-446. DOI:10.1111/vco.12995 2024
DNA Methylation and Its Effects on TRIM29 Gene Expression in the Equine Sarcoid Tissue [0.03%]
马皮脂肉瘤中TRIM29基因表达及其甲基化研究
Semik-Gurgul Ewelina,Zaborowska Anna,Pędziwiatr Rafał et al.
Semik-Gurgul Ewelina et al.
Sarcoids are the most frequently diagnosed dermatological tumour in horses. It is a disease that can affect various species of equids, such as donkeys, mules and zebras. This type of tumour can develop in all horse breeds, regardless of age...
Use of Lomustine and Prednisolone as First-Line Treatment in Canine Multicentric Lymphoma [0.03%]
洛莫司汀和泼尼松龙作为治疗多中心型淋巴瘤的第一线用药在犬类中的应用
Catalucci Chiara,Bianchi Marco Luigi,Treggiari Elisabetta et al.
Catalucci Chiara et al.
Multiagent chemotherapy is considered the most effective treatment for canine high-grade lymphoma; however, due to cost and time requirements, single-agent protocols have also been described. The aim of our study was to evaluate the outcome...
Outcomes of Stereotactic Radiation Therapy Versus Fractionated Radiation Therapy in 44 Dogs With Pituitary Masses: A Multi-Institutional Retrospective Study (2016-2022) [0.03%]
立体定向放射治疗与分次放射治疗在44只患有垂体肿块的狗中的疗效对比：一项多机构回顾性研究（2016-2022）
Tracy L Gieger,Leanne Magestro,Jillian Walz et al.
Tracy L Gieger et al.
Although canine pituitary masses (PM) are increasingly treated with stereotactic radiotherapy (SRT), historical literature supports superior outcomes with conventional full-course fractionated radiation therapy (FRT). A multi-institutional ...