Use of bone marrow cells is associated with improved outcomes when compared to peripheral blood stem cell after haplo-identical transplants with post transplant cyclophosphamide, a study from of the CTIWP-EBMT [0.03%]
半相合移植后使用环磷酰胺,骨髓细胞的使用与外周血干细胞相比可获得更好的疗效:CTIWP-EBMT的一项研究
Vanderson Rocha,Myriam Labopin,Anna Maria Raiola et al.
Vanderson Rocha et al.
Few studies analyzed the impact of bone marrow (BM) or peripheral blood stem cells (PBSC) on outcomes after haploidentical transplantation using post-cyclophosphamide (Haplo-PTCY). We analyzed 8854 adults with malignant disorders, given a f...
Comparison of outcomes of BuCy versus BuCyMel as preparation for allogeneic HSCT in infants with acute myeloid leukemia in first complete remission: a multicenter study from the EBMT PDWP [0.03%]
匹鲁卡布和美司那对儿童急性髓系白血病首次完全缓解行异基因造血干细胞移植预处理效果的多中心研究:EBMT儿科工作组的一项研究
Andre Manfred Willasch,Claire Horgan,Christina Peters et al.
Andre Manfred Willasch et al.
Allogeneic haematopoietic stem cell transplantation (HSCT) is an essential treatment component for high-risk paediatric acute myeloid leukaemia (AML), but the choice of the optimal conditioning regimen remains controversial. We compared out...
Low-dose post-transplant cyclophosphamide in combination with low-dose alemtuzumab for graft-versus-host-disease prevention in mismatched unrelated allogeneic stem cell transplantation is associated with improved outcomes and reduced toxicity [0.03%]
低剂量移植后环磷酰胺联合低剂量阿仑单抗预防错配无关供者的同种异基因干细胞移植后的移植物抗宿主病可改善结局并降低毒性
Ioanna Lazana,Konstantinos Gkirkas,Ioannis Konstantellos et al.
Ioanna Lazana et al.
Post-transplant cyclophosphamide (PTCy) has been explored as GvHD prophylaxis in matched related and unrelated donor transplants with encouraging outcomes, although at the cost of increased toxicity. A prospective, single-center study was c...
Changing scenario in prevention and management of CMV infections in pediatric hematopoietic stem cell transplant patients [0.03%]
儿童造血干细胞移植患者预防和治疗巨细胞病毒感染的现状变迁
Federica Galaverna,Jan Styczynski,Per Ljungman
Federica Galaverna
This review aims to show new insights into the prevention and management of cytomegalovirus (CMV) infections in pediatric hematopoietic stem cell transplant (HCT) recipients. CMV-seropositivity in pediatric recipients/donors (R/D) is lower ...