China is planning to land people on the Moon - and might beat the United States to it [0.03%]
中国正计划载人登月可能会抢在美国之前成功登月
Jonathan O&#x;Callaghan
Jonathan O&#x;Callaghan
Holly Newson
Holly Newson
Dalia Halawani,Yiqun Wang,Jiaxi Li et al.
Dalia Halawani et al.
Axon regeneration is limited in the mammalian central nervous system1. Neurons must balance stress responses with regenerative demands after axonal injury2, but the mechanisms remain unclear. Here we identify aryl hydrocarbon receptor (AhR)...
Lopa Bhatt,Edgar Abarca Morales,Abigail Y Jiang et al.
Lopa Bhatt et al.
The discovery of high-temperature superconductivity in bulk La3Ni2O7 under high hydrostatic pressure1-4 and biaxial compression in epitaxial thin films5-8 has ignited significant interest in understanding the interplay between atomic and el...
Tianhao Lei,Michael R Scheid,Robert D Flint et al.
Tianhao Lei et al.
Cortical high gamma-band activity (HGA) is used in many scientific investigations1-18, yet its biophysical source is a matter of debate. Two leading hypotheses are that HGA predominantly represents summed postsynaptic potentials or-more com...
A µ-opioid receptor superagonist analgesic with minimal adverse effects [0.03%]
一种副作用小的µ型阿片受体超效激动剂止痛药
Juan L Gomez,Emilya N Ventriglia,Zachary J Frangos et al.
Juan L Gomez et al.
Developing safe and effective pain medications is an ongoing challenge for human health. Agonists for the µ-opioid receptor (MOR) are essential pain medications, but their high intrinsic efficacy also induces adverse side effects, includin...
Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair [0.03%]
CUX2神经元外扩需要DNA修复功能的适应性变化
Wenlong Xia,Laura Morcom,Zhaoyang Xu et al.
Wenlong Xia et al.
During mammalian evolution, excitatory neurons in upper cortical layer 2 and layer 3 (L2/3) have shown a disproportionate expansion compared with other layers1-4. Replicative expansion of cortical neural progenitors is associated with consi...
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation [0.03%]
DNA损伤负担导致神经炎症中选择性CUX2神经元丢失
Laura Morcom,Wenlong Xia,Zhaoyang Xu et al.
Laura Morcom et al.
Neurodegeneration shows regional and cell-type-specific patterns in ageing and disease1, but the underlying mechanisms for cell-type-specific neuronal losses remain poorly understood. Previous studies have shown that upper cortical layer th...
Huang Fang,Xiaotian Li,Wensi Sun et al.
Huang Fang et al.
Complex lattices that combine low- and high-order rotational symmetries underpin functional materials ranging from kagome superconductors1-3 to auxetic mechanical networks4 and photonic crystals with topologically protected states5-7. Howev...