Acquired genetic and cell-state changes in IDH-mutant glioma progression [0.03%]
IDH突变型胶质瘤进展中的获得性遗传和细胞状态改变
Kevin C Johnson,Avishay Spitzer,Frederick S Varn et al.
Kevin C Johnson et al.
Gliomas with mutant isocitrate dehydrogenase (IDH) are malignant brain tumours that typically arise in early to mid-adulthood and nearly always recur following treatment1,2. However, the genetic and cellular-state changes that drive IDH-mut...
Teosinte alleles enhance nitrogen assimilation and seed protein in maize [0.03%]
玉米中的刍草基因增强氮同化和籽粒蛋白质积累
Yongcai Huang,Yidong Zhu,Yahui Cui et al.
Yongcai Huang et al.
During maize (Zea mays L.) domestication, seed protein content sharply declined1,2. In plants, glutamine and asparagine levels are closely correlated with protein content3,4. Asparagine is synthesized from glutamine, a process catalysed by ...
Anzhi Sheng,Qi Su,Alex McAvoy et al.
Anzhi Sheng et al.
Cooperation is typically seen as the ideal outcome in a social dilemma. Because cooperators are vulnerable to exploitation, much of the literature has focused on mechanisms, such as spatial structure, that support prosocial behaviour and th...
Di Chen,Lulu Gao,Shujun Li et al.
Di Chen et al.
Efficient nitrogen assimilation is important for sustainable agriculture1, yet its subcellular organization remains unknown. Here we show that plastoglobules (PGs) in the chloroplasts of mesophyll cells function as a metabolic hub that orch...
Qi Wei,Jonah S Peter,Hui Ren et al.
Qi Wei et al.
Superfluorescence (SF) is the collective emission of intense, coherent light from an interacting ensemble of quantum emitters1-4. Although SF has been observed in several solid-state materials5-8, the spontaneous generation of circularly po...
Shudong Chen,Yupan Zou,Huanshuo Cui et al.
Shudong Chen et al.
Cold weather cause severe crop losses. Climate change exacerbates the unpredictability and frequency of such weather events, highlighting the need for cold-resilient crops1. Cold-induced pollen abortion and reproductive failure during flowe...
LASER couples damage sensing to ESCRT assembly for lysosome repair [0.03%]
激光复合物将溶酶体损伤感应与ESCRT装配偶联起来以修复溶酶体
Claire S Goul,Aakriti Jain,Samira Yitiz et al.
Claire S Goul et al.
Lysosomal membrane integrity is essential for cell survival, but how damage sensing is spatiotemporally coupled to repair remains poorly understood. Recruitment and assembly of endosomal sorting complex required for transport (ESCRT) I-III ...
Alexandra Schmuck,Tiago G A Belé,Daniël Withoeck et al.
Alexandra Schmuck et al.
Increasing recycling rates requires not only better technologies but also smarter collection of plastic packaging waste1. Source separation-sorting materials such as plastics and metals at the household level-captures substantial waste volu...
High-fidelity modular skeletons authenticate a Cambrian origin for Bryozoa [0.03%]
高保真模块化骨骼证实了苔藓动物门的寒武纪起源
Baopeng Song,Zhifei Zhang,Luke C Strotz et al.
Baopeng Song et al.
The major animal body plans originated during the Cambrian explosion, yet the phylum Bryozoa has remained a conspicuous exception to this pattern1. The initial discovery of Protomelission gatehousei2 provided compelling evidence for a Cambr...
Jianhao Zhang,Jake J Gristey,Graham Feingold
Jianhao Zhang
Earth's albedo is fundamental to the planetary energy budget1. The Northern Hemisphere (NH) and Southern Hemisphere (SH) contribute essentially equally to the planetary albedo-a remarkable yet puzzling phenomenon known as hemispheric albedo...