Substrates mimicking the blastocyst geometry revert pluripotent stem cell to naivety [0.03%]
模仿胚囊形状的基质可使多能干细胞回复到 naive 状态
Xun Xu,Weiwei Wang,Yue Liu et al.
Xun Xu et al.
Naive pluripotent stem cells have the highest developmental potential but their in vivo existence in the blastocyst is transient. Here we report a blastocyst motif substrate for the in vitro reversion of mouse and human pluripotent stem cel...
C Daniel Frisbie
C Daniel Frisbie
Gal Sandik,Johannes Feist,Francisco J García-Vidal et al.
Gal Sandik et al.
Molecules are the building blocks of all of nature's functional components, serving as the machinery that captures, stores and releases energy or converts it into useful work. However, molecules interact with each other over extremely short...
Pedro Lavrador,Beatriz S Moura,José Almeida-Pinto et al.
Pedro Lavrador et al.
Leveraging human cells as materials precursors is a promising approach for fabricating living materials with tissue-like functionalities and cellular programmability. Here we describe a set of cellular units with metabolically engineered gl...
Transitioning metal-organic frameworks from the laboratory to market through applied research [0.03%]
通过应用研究将金属有机框架材料从实验室推向市场
Ashley M Wright,Matthew T Kapelewski,Stefan Marx et al.
Ashley M Wright et al.
Metal-organic frameworks (MOFs) have captivated researchers for over 25 years, yet few have successfully transitioned to commercial markets. This Perspective elucidates the progress, challenges and opportunities in moving MOFs to market, fo...
A drug-mediated organic electrochemical transistor for robustly reusable biosensors [0.03%]
一种药物介导的有机电化学晶体管用于稳健可重复使用的生物传感器
Ziling Jiang,Dekai Ye,Lanyi Xiang et al.
Ziling Jiang et al.
Reusable point-of-care biosensors offer a cost-effective solution for serial biomarker monitoring, addressing the critical demand for tumour treatments and recurrence diagnosis. However, their realization has been limited by the contradicto...
Helical peptide structure improves conductivity and stability of solid electrolytes [0.03%]
螺旋肽结构可提高固态电解质的导电性和稳定性
Yingying Chen,Tianrui Xue,Chen Chen et al.
Yingying Chen et al.
Ion transport is essential to energy storage, cellular signalling and desalination. Polymers have been explored for decades as solid-state electrolytes by either adding salt to polar polymers or tethering ions to the backbone to create less...
A time of changes [0.03%]
变革的时代
Theodore Hueckel,Robert J Macfarlane
Theodore Hueckel
A pattern of villification [0.03%]
抹黑的套路
Philip Ball
Philip Ball