Sometimes one just isn't enough: do vertebrates contain an H2A.Z hyper-variant? [0.03%]
有时候一个基因产物是不够的：脊椎动物中存在H2A.Z超变体吗？
Monika Mehta,Hyun-Soo Kim,Michael-Christopher Keogh
Monika Mehta
How much functional specialization can one component histone confer on a single nucleosome? The histone variant H2A.Z seems to be an extreme example. Genome-wide distribution maps show non-random (and evolutionarily conserved) patterns, wit...
Jamie L Inman,Mina J Bissell
Jamie L Inman
Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecti...
Top ten in journal of biology in 2009: stem cells, influenza, pit bulls, Darwin, and more [0.03%]
2009年《生物学通讯》十大新闻：干细胞、流感、比特犬、达尔文等
Miranda Robertson
Miranda Robertson
Editorial
Journal of biology. 2009;8(12):102. DOI:10.1186/jbiol210 2009
Miranda Robertson
Miranda Robertson
Editorial
Journal of biology. 2009;8(11):94. DOI:10.1186/jbiol209 2009
Thomas F Schilling,Pierre Le Pabic
Thomas F Schilling
Zebrafish are a powerful system for studying the early embryonic events that form the skull and face, as a model for human craniofacial birth defects such as cleft palate. Signaling pathways that pattern the pharyngeal arches (which contain...
Chromatin 'programming' by sequence--is there more to the nucleosome code than %GC? [0.03%]
染色质的"编程"--碱基组成(%GC)之外的组蛋白密码还有哪些？
Amanda Hughes,Oliver J Rando
Amanda Hughes
The role of genomic sequence in directing the packaging of eukaryotic genomes into chromatin has been the subject of considerable recent debate. A new paper from Tillo and Hughes shows that the intrinsic thermodynamic preference of a given ...
Fernando O Martinez
Fernando O Martinez
Human monocytes can be divided into subsets according to their expression or lack of the cell-surface antigen CD16. In papers published recently in the Journal of Proteome Research and in BMC Genomics, two groups publish independent transcr...
Scott C Dawson,Kari D Hagen
Scott C Dawson
The use of cultivation-independent approaches to map microbial diversity, including recent work published in BMC Biology, has now shown that protists, like bacteria/archaea, are much more diverse than had been realized. Uncovering eukaryoti...
Emily Marcinkevicius,Rodrigo Fernandez-Gonzalez,Jennifer A Zallen
Emily Marcinkevicius
Sandrine Etienne-Manneville
Sandrine Etienne-Manneville
Although proteins involved in determining apical-basal cell polarity have been directly linked to tumorigenesis, their precise roles in this process remain unclear. A recent report in BMC Biology clarifies the signaling pathways that contro...