How do terrestrial Antarctic organisms survive in their harsh environment? [0.03%]
陆地南极生物是如何在严酷的环境中生存的？
David A Wharton,Craig J Marshall
David A Wharton
Anhydrobiosis, or extreme desiccation tolerance, is one of the strategies that allows terrestrial Antarctic organisms to survive in a harsh environment. A new study in BMC Genomics analyses gene expression in an Antarctic nematode during de...
John Tower,Michelle Arbeitman
John Tower
Several possible and potentially overlapping genetic mechanisms have been suggested to explain differences in life span between males and females. Two recent papers in BMC Evolutionary Biology on the effects of inbreeding provide additional...
Aurelie Vandenbeuch,Sue C Kinnamon
Aurelie Vandenbeuch
Taste cells regularly generate action potentials, but their functional significance in taste signaling is unclear. A paper in BMC Neuroscience reveals the identity of the voltage-gated Na+ channels underlying action potentials, providing th...
David W Burt
David W Burt
The domesticated cow is the latest farm animal to have its genome sequenced and deciphered. The members of the Bovine Genome Consortium have published a series of papers on the assembly and what the sequence reveals so far about the biology...
Anthony V Capuco,R Michael Akers
Anthony V Capuco
The presence of mammary glands is the defining morphological feature of mammals. The recent assembly of the bovine genome and a report in Genome Biology that links the milk and lactation data of bovine and other mammalian genomes will help ...
Hans Ellegren
Hans Ellegren
Analyses of mitochondrial DNA (mtDNA) have challenged the concept that genetic diversity within populations is governed by effective population size and mutation rate. A recent study in BMC Evolutionary Biology shows that variation in the r...
The genomic 'inner fish' and a regulatory enigma in the vertebrates [0.03%]
.genomic "内鱼" 和脊椎动物中的一个调控谜题
John Malone,Brian Oliver
John Malone
Information on how genomic information from fish to human encodes the same tissues has until now emerged one gene at a time. The study published in this issue now provides lists of genes and their expression levels for 20 vertebrate tissues...
Trudy F C Mackay
Trudy F C Mackay
Shun J Lee,Jean Y J Wang
Shun J Lee
The protein kinase inhibitor imatinib, also known as Gleevec, has been a notable success in treating chronic myelogenous leukemia. A recent paper in BMC Structural Biology reports a 1.75 A crystal structure of imatinib bound to the oxidored...
Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria [0.03%]
重建古细菌转录调控网络：来自放线菌的启示
Thiago M Venancio,L Aravind
Thiago M Venancio
Reconstruction of transcriptional regulatory networks of uncharacterized bacteria is a main challenge for the post-genomic era. Recent studies, including one in BMC Systems Biology, address this problem in the relatively underexplored actin...