Development of a novel glycoengineering platform for the rapid production of conjugate vaccines [0.03%]
一种新型糖工程平台的开发，用于结合疫苗的快速生产
Sherif Abouelhadid,Elizabeth R Atkins,Emily J Kay et al.
Sherif Abouelhadid et al.
Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. However, conjugate vaccine assembly and production have se...
Fused expression of Sm1-Chit42 proteins for synergistic mycoparasitic response of Trichoderma afroharzianum on Botrytis cinerea [0.03%]
Sm1-Chit42融合表达促进哈茨木霉对灰葡萄孢的协同重寄生响应
Hongyi Liu,Shaoqing Wang,Bo Lang et al.
Hongyi Liu et al.
Sm1 and Chit42 of Trichoderma have been universally confirmed as crucial biocontrol factors against pathogen infection through induced resistance and mycoparasitism, respectively. However, not enough work has been conducted to understand th...
Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA) [0.03%]
异源表达豌豆种子毒蛋白PA1并融合雪莲凝集素增强其对蚜虫的毒力
Jake S De-Thier,Prashant Pyati,Jack Bell et al.
Jake S De-Thier et al.
Background: New bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use of synthetic chemical pesticides and to combat growing levels of pest...
Mutation in yl-HOG1 represses the filament-to-yeast transition in the dimorphic yeast Yarrowia lipolytica [0.03%]
酵母样真菌油囊酵母中的yl-HOG1突变抑制丝状体向芽殖体的转化现象
Dorota A Rzechonek,Mateusz Szczepańczyk,Aleksandra M Mirończuk
Dorota A Rzechonek
Background: Yarrowia lipolytica is a dimorphic fungus, which switches from yeast to filament form in response to environmental conditions. For industrial purposes it is important to lock cells in the yeast or filamentous ...
Rhizopus stolonifer biomass catalytic transesterification capability: optimization of cultivation conditions [0.03%]
匍枝根霉菌株催化转酯作用能力：培养条件优化研究
Nadeem I Elhussieny,Heba A El-Refai,Sayeda S Mohamed et al.
Nadeem I Elhussieny et al.
Background: Using fungal biomass for biocatalysis is a potential solution for the expensive cost of the use o enzymes. Production of fungal biomass with effective activity requires optimizing the cultivation conditions. ...
Impact of mixing insufficiencies on L-phenylalanine production with an Escherichia coli reporter strain in a novel two-compartment bioreactor [0.03%]
混合不充分对新型双室生物反应器中携带大肠杆菌报告菌株生产L-苯丙氨酸的影响
Manh Dat Hoang,Ingmar Polte,Lukas Frantzmann et al.
Manh Dat Hoang et al.
Background: The omnipresence of population heterogeneity in industrial bioprocesses originates from prevailing dynamic bioprocess conditions, which promote differences in the expression of cellular characteristics. Despit...
Copper biosorption by Bacillus pumilus OQ931870 and Bacillus subtilis OQ931871 isolated from Wadi Nakheil, Red Sea, Egypt [0.03%]
来自埃及红海瓦迪纳克海尔的BacilluspumilusOQ931870和BacillussubtilisOQ931871铜生物吸附研究
Amal William Danial,Fatma Mohamed Dardir
Amal William Danial
Background: Despite being necessary, copper is a toxic heavy metal that, at high concentrations, harms the life system. The parameters that affect the bioreduction and biosorption of copper are highly copper-resistant bac...
Conversion of methionine biosynthesis in Escherichia coli from trans- to direct-sulfurylation enhances extracellular methionine levels [0.03%]
由转硫途径到直接硫酸化的甲硫氨酸生物合成转化可增强大肠杆菌胞外甲硫氨酸的积累
Nadya Gruzdev,Yael Hacham,Hadar Haviv et al.
Nadya Gruzdev et al.
Methionine is an essential amino acid in mammals and a precursor for vital metabolites required for the survival of all organisms. Consequently, its inclusion is required in diverse applications, such as food, feed, and pharmaceuticals. Alt...
Development of the thermophilic fungus Myceliophthora thermophila into glucoamylase hyperproduction system via the metabolic engineering using improved AsCas12a variants [0.03%]
利用改良的AsCas12a变体进行代谢工程将高温真菌Myceliophthora thermophila开发成高产葡萄糖淀粉酶系统
Zhijian Zhu,Manyu Zhang,Dandan Liu et al.
Zhijian Zhu et al.
Background: Glucoamylase is an important enzyme for starch saccharification in the food and biofuel industries and mainly produced from mesophilic fungi such as Aspergillus and Rhizopus species. Enzymes produced from ther...
Use of the mCherry fluorescent protein to optimize the expression of class I lanthipeptides in Escherichia coli [0.03%]
mCherry荧光蛋白在优化枯草芽孢杆菌核糖体P1蛋白抗性基因表达中的应用及机制研究
Winschau F Van Zyl,Anton D Van Staden,Leon M T Dicks et al.
Winschau F Van Zyl et al.
Background: Lanthipeptides are a rapidly expanding family of ribosomally synthesized and post-translationally modified natural compounds with diverse biological functions. Lanthipeptide structural and biosynthetic genes c...